Role of Protein Lysine Acetylation in the Pathogenesis and Treatment of Obesity and Metabolic Syndrome DOI Creative Commons
Zhaopeng Li, Yancheng Song, Li Zhao

et al.

Current Obesity Reports, Journal Year: 2025, Volume and Issue: 14(1)

Published: March 13, 2025

This review aimed to highlight the known role of histone deacetylases (HDACs) and lysine acetyltransferases (KATs) in individuals with obesity, better understand HDACs KATs enzymes obesity related metabolic disorders. Numerous cellular activities, including DNA replication, repair, cell cycle regulation, RNA splicing, signal transmission, function, protein stability, transportation, transcriptional are influenced by acetylation. Protein acetylation serves several purposes, which not only contribute development disorders linked but also hold promise for therapeutic approaches. The current study demonstrates that control details advancements made diseases, It contributes our understanding function mechanism MS offers a fresh method treating these diseases.

Language: Английский

Role of Protein Lysine Acetylation in the Pathogenesis and Treatment of Obesity and Metabolic Syndrome DOI Creative Commons
Zhaopeng Li, Yancheng Song, Li Zhao

et al.

Current Obesity Reports, Journal Year: 2025, Volume and Issue: 14(1)

Published: March 13, 2025

This review aimed to highlight the known role of histone deacetylases (HDACs) and lysine acetyltransferases (KATs) in individuals with obesity, better understand HDACs KATs enzymes obesity related metabolic disorders. Numerous cellular activities, including DNA replication, repair, cell cycle regulation, RNA splicing, signal transmission, function, protein stability, transportation, transcriptional are influenced by acetylation. Protein acetylation serves several purposes, which not only contribute development disorders linked but also hold promise for therapeutic approaches. The current study demonstrates that control details advancements made diseases, It contributes our understanding function mechanism MS offers a fresh method treating these diseases.

Language: Английский

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