Molecules,
Journal Year:
2022,
Volume and Issue:
27(11), P. 3402 - 3402
Published: May 25, 2022
Hundreds
of
billions
commensal
microorganisms
live
in
and
on
our
bodies,
most
which
colonize
the
gut
shortly
after
birth
stay
there
for
rest
lives.
In
animal
models,
bidirectional
communications
between
central
nervous
system
microbiota
(Gut-Brain
Axis)
have
been
extensively
studied,
it
is
clear
that
changes
composition
play
a
vital
role
pathogenesis
various
neurodevelopmental
neurodegenerative
disorders,
such
as
Autism
Spectrum
Disorder,
Alzheimer's
disease,
Parkinson's
Multiple
Sclerosis,
Amyotrophic
Lateral
anxiety,
stress,
so
on.
The
makeup
microbiome
impacted
by
variety
factors,
genetics,
health
status,
method
delivery,
environment,
nutrition,
exercise,
present
understanding
its
metabolites
preservation
brain
functioning
development
aforementioned
neurological
illnesses
summarized
this
review
article.
Furthermore,
we
discuss
current
breakthroughs
use
probiotics,
prebiotics,
synbiotics
to
address
illnesses.
Moreover,
also
discussed
boron-based
diet
memory,
boron
relation,
anti-inflammatory
agents,
diseases.
addition,
coming
years,
reagents
will
significant
improve
dysbiosis
open
new
areas
researchers.
Critical Care,
Journal Year:
2022,
Volume and Issue:
26(1)
Published: July 13, 2022
Sepsis
is
a
potentially
fatal
condition
caused
by
dysregulation
of
the
body's
immune
response
to
an
infection.
Sepsis-induced
liver
injury
considered
strong
independent
prognosticator
death
in
critical
care
unit,
and
there
anatomic
accumulating
epidemiologic
evidence
that
demonstrates
intimate
cross
talk
between
gut
liver.
Intestinal
barrier
disruption
microbiota
dysbiosis
during
sepsis
result
translocation
intestinal
pathogen-associated
molecular
patterns
damage-associated
into
systemic
circulation.
The
essential
for
regulating
defense
infections
via
mechanisms
such
as
bacterial
clearance,
lipopolysaccharide
detoxification,
cytokine
acute-phase
protein
release,
inflammation
metabolic
regulation.
When
inappropriate
or
overwhelming
occurs
liver,
impaired
capacity
pathogen
clearance
hepatic
disturbance
can
further
impairment
increased
composition
diversity
microbiota.
Therefore,
interaction
potential
therapeutic
target.
This
review
outlines
gut-liver
(gut-liver
axis)
sepsis.
International Journal of Molecular Sciences,
Journal Year:
2022,
Volume and Issue:
23(11), P. 6097 - 6097
Published: May 29, 2022
Diabetes
and
obesity
are
metabolic
diseases
that
have
become
alarming
conditions
in
recent
decades.
Their
rate
of
increase
is
becoming
a
growing
concern
worldwide.
Recent
studies
established
the
composition
dysfunction
gut
microbiota
associated
with
development
diabetes.
For
this
reason,
strategies
such
as
use
prebiotics
to
improve
intestinal
microbial
structure
function
popular.
Consumption
for
modulating
results
production
metabolites
short-chain
fatty
acids
play
essential
roles
reducing
blood
glucose
levels,
mitigating
insulin
resistance,
inflammation,
promoting
secretion
glucagon-like
peptide
1
host,
accounts
observed
remission
diseases.
Prebiotics
can
be
either
naturally
extracted
from
non-digestible
carbohydrate
materials
or
synthetically
produced.
In
review,
we
discussed
current
findings
on
how
may
influence
host
metabolism
promote
health.
We
provided
evidence
various
show
ability
prebiotic
consumption
alter
profile,
functions,
physiology
alleviate
diabetes
obesity.
conclude
among
other
things
application
systems
biology
coupled
bioinformatics
could
ascertaining
exact
mechanisms
behind
prebiotic–gut
microbe–host
interactions
required
improvement.
FEMS Microbiology Ecology,
Journal Year:
2022,
Volume and Issue:
98(5)
Published: April 6, 2022
Environmental
pH
is
a
critical
parameter
for
maintenance
of
the
gut
microbiota.
Here,
impact
on
microbiota
luminal
and
mucosal
community
structure
short
chain
fatty
acid
(SCFA)
production
was
evaluated
in
vitro,
data
compiled
to
reveal
donor-independent
response
an
increase
or
decrease
environmental
pH.
The
results
found
that
raising
significantly
increased
richness
decreased
evenness.
This
corresponded
with
abundance
Ruminococcaceae
Ruminococcus
Erysipelotrichaceae
Erysipelatoclostridium,
Coriobacteriaceae
Collinsella
Enterobacteriaceae
Shigella
both
communities.
Total
SCFA
levels
were
higher,
primarily
due
acetic
2-methylbutanoic
acids.
Lowering
evenness
richness.
Lachnospiraceae
Enterocloster,
Veillonellaceae
Megasphaera,
Sporomusa,
Eubacterium,
Alcaligenaceae
Sutterella,
Odoribacteraceae
Butyricimonas,
Fusobacteriaceae
Fusobacterium,
Phascolarctobacterium,
multiple
species
lower,
observed
drop
propionic
acids,
butyric
valeric
Taken
together,
these
indicate
alterations
can
modulate
function,
some
changes
may
occur
manner.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(11), P. 3402 - 3402
Published: May 25, 2022
Hundreds
of
billions
commensal
microorganisms
live
in
and
on
our
bodies,
most
which
colonize
the
gut
shortly
after
birth
stay
there
for
rest
lives.
In
animal
models,
bidirectional
communications
between
central
nervous
system
microbiota
(Gut-Brain
Axis)
have
been
extensively
studied,
it
is
clear
that
changes
composition
play
a
vital
role
pathogenesis
various
neurodevelopmental
neurodegenerative
disorders,
such
as
Autism
Spectrum
Disorder,
Alzheimer's
disease,
Parkinson's
Multiple
Sclerosis,
Amyotrophic
Lateral
anxiety,
stress,
so
on.
The
makeup
microbiome
impacted
by
variety
factors,
genetics,
health
status,
method
delivery,
environment,
nutrition,
exercise,
present
understanding
its
metabolites
preservation
brain
functioning
development
aforementioned
neurological
illnesses
summarized
this
review
article.
Furthermore,
we
discuss
current
breakthroughs
use
probiotics,
prebiotics,
synbiotics
to
address
illnesses.
Moreover,
also
discussed
boron-based
diet
memory,
boron
relation,
anti-inflammatory
agents,
diseases.
addition,
coming
years,
reagents
will
significant
improve
dysbiosis
open
new
areas
researchers.
