Biofilm Battle: New transformative tactics to tackle the bacterial biofilm infections
Microbial Pathogenesis,
Journal Year:
2025,
Volume and Issue:
199, P. 107277 - 107277
Published: Jan. 5, 2025
Language: Английский
Tissue Engineering and Biosensing Applications of Carbon-Based Nanomaterials
Biomedical Engineering Advances,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100145 - 100145
Published: Jan. 1, 2025
Language: Английский
Advanced Nanotechnological Approaches for Biofilm Prevention and Control
Applied Sciences,
Journal Year:
2024,
Volume and Issue:
14(18), P. 8137 - 8137
Published: Sept. 10, 2024
Biofilm-associated
infections
present
a
significant
challenge
in
modern
medicine,
primarily
due
to
their
resilience
and
resistance
conventional
treatments.
These
occur
when
bacteria
form
biofilms,
protective
layers
formed
by
bacterial
communities,
which
are
notoriously
resistant
traditional
antibiotics
on
surfaces
such
as
medical
implants
biological
surfaces,
making
eradication
with
standard
difficult.
This
leads
persistent
infections,
imposing
substantial
economic
burden
healthcare
systems.
The
urgency
find
alternative
treatments
is
critical
current
methods
insufficient
costly.
Innovative
approaches,
nanotechnology-based
therapies,
offer
promising
alternatives
targeting
biofilms
more
effectively
reducing
the
need
for
invasive
procedures.
Nanocarriers
hold
promise
fight
against
biofilm-associated
infections.
can
penetrate
than
treatments,
delivering
higher
concentrations
of
or
other
antimicrobial
agents
precisely
where
they
needed.
targeted
approach
not
only
enhances
efficacy
but
also
minimizes
potential
side
effects.
development
nanocarrier-based
therapies
crucial
overcoming
limitations
ultimately
improving
patient
outcomes
In
this
review,
systems,
characteristics,
limitations,
benefits
explored
address
biofilms-related
Additionally,
biofilm
evaluation
models
tests
necessary
preclinical
validation
these
nanosystems
facilitate
clinical
application
addressed.
Language: Английский
Versatile nanomaterials used in combatting biofilm infections
Nanomedicine,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 18
Published: Jan. 31, 2025
Microbial
infections
are
a
pressing
global
health
issue,
exacerbated
by
the
rise
of
antibiotic-resistant
bacteria
due
to
widespread
antibiotic
overuse.
This
resistance
diminishes
effectiveness
current
treatments,
intensifying
need
for
new
antimicrobial
agents
and
innovative
drug
delivery
strategies.
Nanotechnology
presents
promising
solutions,
leveraging
unique
properties
nanomaterials
such
as
tunable
optical
electronic
characteristics,
nanoscale
size,
high
surface-to-volume
ratios.
These
features
enhance
their
versatile
systems.
minireview
classifies
into
four
categories
based
on
mechanisms
action:
thermal
generation,
reactive
oxygen
species
gas
nanocarrier
systems
liposomes,
polymersomes,
metal-organic
frameworks.
Uniquely,
this
review
integrates
comparative
analysis
these
mechanisms,
highlighting
relative
advantages,
limitations,
applications
across
diverse
microbial
targets.
Additionally,
it
identifies
emerging
trends
in
field,
providing
forward-looking
perspective
how
recent
advancements
nanotechnology
can
be
leveraged
address
unmet
clinical
needs.
Finally,
article
discusses
future
directions
opportunities
nanotechnology.
Language: Английский
Advancing gut microbiome insights: Graphene quantum dot nanobiosensors for microbial metabolite detection
Soheil Sadr,
No information about this author
Shakiba Nazemian,
No information about this author
Shiva Dianaty
No information about this author
et al.
Chemical Engineering Journal,
Journal Year:
2025,
Volume and Issue:
unknown, P. 162954 - 162954
Published: April 1, 2025
Antibacterial and Antibiofilm Activity of Zinc Oxide Quantum Dots against Methicillin‐resistant Staphylococcus aureus
Particle & Particle Systems Characterization,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 25, 2024
Abstract
Antimicrobial
resistance
occurs
mostly
through
the
ineffective
and
unauthorized
use
of
antibiotics
in
both
environment
health
care.
Biofilms
are
a
new
target
search
for
antibacterial
agents.
Here,
sol‐gel
method
is
used
to
produce
zinc
oxide
quantum
dots
(ZnO‐QDs).
The
ZnO‐QDs
show
yellow
emission
at
526
nm
under
360
excitation.
After
that,
ability
as
an
antibiofilm
agent
against
methicillin‐resistant
Staphylococcus
aureus
(MRSA)
examined.
100
samples
collected
from
patients
with
hospital‐acquired
infections
between
December
2020
October
2021
Imamen
Kadhmiyan
Teaching
Hospital
Baghdad
(Iraq).
Out
these
samples,
63
S.
20
out
MRSA.
minimum
inhibitory
concentration
assay
demonstrates
activity
on
MRSA
strains.
Also,
results
that
80,
5,
15%
isolated
strains
strong,
moderate,
weak
or
very
biofilm,
respectively.
effect
strong
moderate
biofilms
reveal
QDs
could
also
inhibit
destroy
biofilm
produced
by
In
addition,
greater
than
their
effect.
Generally,
this
work
offers
insights
into
development
nanomaterials.
Language: Английский