Sinomenine ameliorates bleomycin-induced pulmonary fibrosis by inhibiting the differentiation of fibroblast into myofibroblast DOI Creative Commons

Zuqiong Nie,

Jing Wu,

Jun Xie

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(13), P. e33314 - e33314

Published: June 24, 2024

Language: Английский

Therapeutic Potential of Phytocompounds in Rheumatoid Arthritis: Molecular Insights and Clinical Applications DOI

Md. Zamshed Alam Begh,

Mehrukh Zehravi,

F Mohammad Reza

et al.

Pathology - Research and Practice, Journal Year: 2025, Volume and Issue: unknown, P. 155945 - 155945

Published: March 1, 2025

Language: Английский

Citations

0
Ocimene mitigates pyroptosis through TLR4/NLRP3-mediated mechanisms in CFA-induced inflammation DOI

Iqra Laraib,

Sumera Qasim, Ambreen Malik Uttra

et al.

Inflammopharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Language: Английский

Citations

0
New Perspective on the Treatment of Rheumatic Arthritis Based on “Strengthening Body Resistance (Fú Zhèng)” in the Theory of Co-inhibitory Receptor-regulated T-Cell Immunity DOI Creative Commons
Yifei Xu, Linda L. D. Zhong, Qianqian Liang

et al.

Acupuncture and Herbal Medicine, Journal Year: 2024, Volume and Issue: 4(3), P. 290 - 294

Published: July 16, 2024

Co-inhibitory receptors serve as crucial regulators of T-cell function, playing a pivotal role in modulating the delicate balance between immune tolerance and autoimmunity. Initially identified autoimmune disease models, co-inhibitory receptors, including CTLA-4, PD-1, TIM-3, TIGIT, were found to be integral regulation. Their blockade or absence these models resulted induction exacerbation diseases. Additionally, scholars have observed that on lymphocytes hold potential influence prognosis context chronic inflammation. Consequently, blocking co-suppressor has emerged novel therapeutic approach for inhibiting refractory inflammatory diseases, particularly rheumatoid arthritis. From standpoint traditional Chinese medicine (TCM), treatment arthritis based “strengthening body resistance (Fú Zhèng)” theory can construed regulation modulate body’s function combating This article provides succinct overview anti-inflammatory processes explores research prospects receptor intervention The exploration integrates with relevant formulations.

Language: Английский

Citations

3
Transethosomal gel for enhancing transdermal delivery of natural therapeutics DOI
Soki Daeme Malang,

Shambhavi,

Alakh N. Sahu

et al.

Nanomedicine, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 19

Published: July 26, 2024

Transethosomes, a fusion of transferosomes and ethosomes, combine the advantageous attributes both vesicular systems to enhance deformability skin permeation. While delivery is effective for drug transport, overcoming barrier remains significant challenge, particularly plant-based products with poor permeability. Transethosomes offer promising solution, but their low viscosity retention on surfaces led development transethosomal gels. These gels can entrap unstable high molecular weight herbal extracts, fractions bioactive compounds, facilitating enhanced inner layers skin. This review focuses superior performance transethosomes compared conventional lipid-based nanovesicular systems, offering an advanced approach transdermal drugs improved permeability stability.

Language: Английский

Citations

2
Sinomenine ameliorates bleomycin-induced pulmonary fibrosis by inhibiting the differentiation of fibroblast into myofibroblast DOI Creative Commons

Zuqiong Nie,

Jing Wu,

Jun Xie

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(13), P. e33314 - e33314

Published: June 24, 2024

Language: Английский

Citations

0