Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation DOI Creative Commons

Yinchen Ge,

Jiaci Liu,

Huacheng Tang

et al.

Food Chemistry X, Journal Year: 2024, Volume and Issue: 25, P. 102089 - 102089

Published: Dec. 17, 2024

Highland barley β-glucan (HBG) has attracted increasing attention due to its excellent biological activities. However, the effects of HBG on gut flora and metabolites are unknown. Therefore, microbiota during fermentation were analyzed by 16 s rRNA sequencing untargeted metabolomics. The results showed that could enrich microbial diversity, increase abundance beneficial bacteria, inhibit biology pathogenic bacteria. In addition, increased content short-chain fatty acids decreased broth pH. Metabolomics analyses also such as taurine affected amino acid metabolism, among other pathways. This study lays foundation for application in functional foods.

Language: Английский

Sida cordifolia L. Fraction Ameliorate Renal Injury, Inflammation, Apoptosis and Gene Expression on Cisplatin Induced Acute Kidney Injury: Network Pharmacology, In vivo and In vitro studies DOI Creative Commons
Palash Mitra, Sahadeb Jana,

Pipika Das

et al.

Current Pharmaceutical Analysis, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

Citations

0
Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation DOI Creative Commons

Yinchen Ge,

Jiaci Liu,

Huacheng Tang

et al.

Food Chemistry X, Journal Year: 2024, Volume and Issue: 25, P. 102089 - 102089

Published: Dec. 17, 2024

Highland barley β-glucan (HBG) has attracted increasing attention due to its excellent biological activities. However, the effects of HBG on gut flora and metabolites are unknown. Therefore, microbiota during fermentation were analyzed by 16 s rRNA sequencing untargeted metabolomics. The results showed that could enrich microbial diversity, increase abundance beneficial bacteria, inhibit biology pathogenic bacteria. In addition, increased content short-chain fatty acids decreased broth pH. Metabolomics analyses also such as taurine affected amino acid metabolism, among other pathways. This study lays foundation for application in functional foods.

Language: Английский

Citations

0