Advances in pancreatic cancer diagnosis: from DNA methylation to AI-Assisted imaging DOI

Rohit Sharma,

Kumari Komal,

Sourabh Kumar

et al.

Expert Review of Molecular Diagnostics, Journal Year: 2025, Volume and Issue: unknown

Published: May 19, 2025

Pancreatic Cancer (PC) is a highly aggressive tumor that mainly diagnosed at later stages. Various imaging technologies, such as CT, MRI, and EUS, possess limitations in early PC diagnosis. Therefore, this review article explores the various innovative biomarkers for detection, DNA methylation, Noncoding RNAs, proteomic biomarkers, role of AI detection Innovative methylation genes, show higher specificity sensitivity Additionally, non-coding long RNAs (lncRNAs) microRNAs, high diagnostic accuracy serve prognostic biomarkers. retain different body fluids. Apart from this, utilization showed surpassed radiologist's performance detection. The combination advanced can revolutionize However, large-scale, prospective studies are needed to validate its clinical utility. Further. standardization biomarker panels algorithms vital step toward their reliable applications ultimately improving patient outcomes.

Language: Английский

A Comprehensive Review on Revolutionizing Pancreatic Cancer Treatment: Liposomal Innovations DOI

Rohit Sharma,

Km Komal,

Sourabh Kumar

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 107032 - 107032

Published: May 1, 2025

Language: Английский

Citations

0
Advances in pancreatic cancer diagnosis: from DNA methylation to AI-Assisted imaging DOI

Rohit Sharma,

Kumari Komal,

Sourabh Kumar

et al.

Expert Review of Molecular Diagnostics, Journal Year: 2025, Volume and Issue: unknown

Published: May 19, 2025

Pancreatic Cancer (PC) is a highly aggressive tumor that mainly diagnosed at later stages. Various imaging technologies, such as CT, MRI, and EUS, possess limitations in early PC diagnosis. Therefore, this review article explores the various innovative biomarkers for detection, DNA methylation, Noncoding RNAs, proteomic biomarkers, role of AI detection Innovative methylation genes, show higher specificity sensitivity Additionally, non-coding long RNAs (lncRNAs) microRNAs, high diagnostic accuracy serve prognostic biomarkers. retain different body fluids. Apart from this, utilization showed surpassed radiologist's performance detection. The combination advanced can revolutionize However, large-scale, prospective studies are needed to validate its clinical utility. Further. standardization biomarker panels algorithms vital step toward their reliable applications ultimately improving patient outcomes.

Language: Английский

Citations

0