Diagnosis and treatment status of inoperable locally advanced breast cancer and the application value of inorganic nanomaterials DOI Creative Commons

Linxuan Wu,

Chuan He,

Tingting Zhao

et al.

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: June 25, 2024

Abstract Locally advanced breast cancer (LABC) is a heterogeneous group of that accounts for 10–30% cases. Despite the ongoing development current treatment methods, LABC remains severe and complex public health concern around world, thus prompting urgent requirement innovative diagnosis strategies. The primary challenges are inoperable clinical status ineffective local control methods. With rapid advancement nanotechnology, inorganic nanoparticles (INPs) exhibit potential application prospect in diagnosing treating cancer. Due to unique inherent characteristics INPs, different functions can be performed via appropriate modifications constructions, making them suitable imaging technology strategies schemes. INPs improve efficacy conventional radiotherapy treatment. In face LABC, have proposed new therapeutic methods fostered evolution novel such as photothermal photodynamic therapy, magnetothermal sonodynamic multifunctional nanoplatform. This article reviews advances accurate offers insights overcome existing difficulties management. Graphical

Language: Английский

Recent Advances in Gold Nanocluster-Based Biosensing and Therapy: A Review DOI Creative Commons
Yang Lü,

Pengqi Hou,

Jingyi Wei

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(7), P. 1574 - 1574

Published: April 1, 2024

Gold nanoclusters (Au NCs) with bright emission and unique chemical reactivity characters have been widely applied for optical sensing imaging. With a combination of surface modifications, effective therapeutic treatments tumors are realized. In this review, we summarize the recently adopted biosensing therapy events based on Au NCs. Homogeneous fluorometric systems toward various targets, including ions, small molecules, reactive oxygen species, biomacromolecules, cancer cells, bacteria, in vitro vivo, presented by turn-off, turn-on, ratiometric tactics. The applications concluded three aspects: photodynamic therapy, photothermal as drug carrier. basic mechanisms performances these introduced. Finally, review highlights challenges future trend NC-based systems.

Language: Английский

Citations

9
Gold Nanobiosensors: Pioneering Breakthroughs in Precision Breast Cancer Detection DOI Creative Commons
Soheil Sadr, Ashkan Hajjafari, Abbas Rahdar

et al.

European Journal of Medicinal Chemistry Reports, Journal Year: 2024, Volume and Issue: unknown, P. 100238 - 100238

Published: Oct. 1, 2024

Language: Английский

Citations

4
Diagnosis and treatment status of inoperable locally advanced breast cancer and the application value of inorganic nanomaterials DOI Creative Commons

Linxuan Wu,

Chuan He,

Tingting Zhao

et al.

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: June 25, 2024

Abstract Locally advanced breast cancer (LABC) is a heterogeneous group of that accounts for 10–30% cases. Despite the ongoing development current treatment methods, LABC remains severe and complex public health concern around world, thus prompting urgent requirement innovative diagnosis strategies. The primary challenges are inoperable clinical status ineffective local control methods. With rapid advancement nanotechnology, inorganic nanoparticles (INPs) exhibit potential application prospect in diagnosing treating cancer. Due to unique inherent characteristics INPs, different functions can be performed via appropriate modifications constructions, making them suitable imaging technology strategies schemes. INPs improve efficacy conventional radiotherapy treatment. In face LABC, have proposed new therapeutic methods fostered evolution novel such as photothermal photodynamic therapy, magnetothermal sonodynamic multifunctional nanoplatform. This article reviews advances accurate offers insights overcome existing difficulties management. Graphical

Language: Английский

Citations

2