Parietal alpha tACS shows inconsistent effects on visuospatial attention

PLoS ONE, Journal Year: 2021, Volume and Issue: 16(8), P. e0255424 - e0255424

Published: Aug. 5, 2021

Transcranial alternating current stimulation (tACS) is a popular technique that has been used for manipulating brain oscillations and inferring causality regarding the brain-behaviour relationship. Although it promising tool, variability of tACS results raised questions robustness reproducibility its effects. Building on recent research using to modulate visuospatial attention, we here attempted replicate findings lateralized parietal at alpha frequency induce change in attention bias away from contra- towards ipsilateral visual hemifield. 40 healthy participants underwent two separate sessions where either 10 Hz or sham was applied via high-density montage over left cortex 1.5 mA 20 min, while performance assessed an endogenous task. Task parameters were chosen match those previous studies reporting positive Unlike these studies, did not observe affect deployment processing across hemifields as compared sham. Likewise, additional resting electroencephalography immediately offline reveal any notable effects individual power frequency. Our study emphasizes need more replication systematic investigations factors drive

Language: Английский

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Central nervous system physiology

Clinical Neurophysiology, Journal Year: 2021, Volume and Issue: 132(12), P. 3043 - 3083

Published: Oct. 14, 2021

This is the second chapter of series on use clinical neurophysiology for study movement disorders. It focusses methods that can be used to probe neural circuits in brain and spinal cord. These include supraspinal reflexes integrity transmission specific pathways; transcranial stimulation such as magnetic direct current stimulation, which activate or modulate (respectively) activity populations central neurones; EEG methods, both conjunction with behavioural measures record pure allow us build conceptual models motor control. The are discussed mainly relation work healthy individuals. Later chapters will focus specifically changes caused by pathology.

Language: Английский

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Comparison of online and offline applications of dual-site transcranial alternating current stimulation (tACS) over the pre-supplementary motor area (preSMA) and right inferior frontal gyrus (rIFG) for improving response inhibition

Neuropsychologia, Journal Year: 2023, Volume and Issue: 191, P. 108737 - 108737

Published: Nov. 22, 2023

The efficacy of transcranial alternating current stimulation (tACS) is thought to be brain state-dependent, such that tACS during task performance would hypothesised offer greater potential for improving compared at rest. However, date, no empirical study has tested this postulation. the effects dual-site beta applied a stop signal (online) same protocol prior (offline) and sham control in 53 young, healthy adults (32 female; 18-35 yrs). right inferior frontal gyrus (rIFG) centre (midline) pre-supplementary motor area (preSMA), which are play critical roles action cancellation, were simultaneously stimulated, sending phase-synchronised 15 min with aim increasing functional connectivity. offline group showed significant within-group improvement response inhibition without showing overt task-related changes connectivity measured EEG analysis, suggesting efficacious inducing behavioural potentially via post-stimulation early plasticity mechanism. In contrast, neither online nor improvements inhibition. analysis revealed significantly increased following medium effect size observed correlation analyses suggested an increase band rest was associated Overall, results indicate both can beneficial inhibitory distinct underlying mechanisms.

Language: Английский

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The potential of noisy galvanic vestibular stimulation for optimizing and assisting human performance

Neuropsychologia, Journal Year: 2021, Volume and Issue: 152, P. 107751 - 107751

Published: Jan. 11, 2021

Language: Английский

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Double-blind randomized N-of-1 trial of transcranial alternating current stimulation for mal de débarquement syndrome

PLoS ONE, Journal Year: 2022, Volume and Issue: 17(2), P. e0263558 - e0263558

Published: Feb. 4, 2022

Background Mal de Débarquement Syndrome (MdDS) is a medically refractory neurotological disorder characterized by persistent oscillating vertigo that follows period of entrainment to motion such as experienced during sea or air travel. Fronto-occipital hypersynchrony may correlate with MdDS symptom severity. Materials and methods Individuals treatment lasting at least 6 months received single administrations three fronto-occipital transcranial alternating current stimulation (tACS) protocols in an “n-of-1” double-blind randomized design: alpha frequency anti-phase, alpha-frequency in-phase, gamma control. Baseline assessments were made on Day 1. The protocol led the most acute reduction symptoms test session 2 was administered for 10–12 stacked sessions given Days 3 through 5 (20-minutes 2-4mA). Pre post changes assessed 1 5. Participants who could clearly choose preferred did better than those not make short-term determination either chose based minimized side effects one protocols. In addition, weekly four baseline seven points Dizziness Handicap Inventory (DHI), Balance Rating Scale (MBRS), Hospital Anxiety Depression (HADS). Results Of 24 participants, 13 7 4 control stimulation. Compared baseline, 10/24 completers noted ≥ 25% reduction, 5/24 ≥50% 2/24 ≥75% intensity from Stimulating slightly higher individual (IAF) stimulating exactly IAF, strategy standardized 10Hz. A one-way repeated measures ANOVA DHI, MBRS, HADS measurements showed significant reductions immediately after improvement increasing post-treatment week 6. Conclusion tACS be effective reducing serve portable neuromodulation alternative longer-term treatment. Stimulation relative IAF important determining optimum [ClinicalTrials.gov study NCT02540616. https://clinicaltrials.gov/ct2/show/NCT02540616 ].

Language: Английский

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