Potentially Inappropriate Medication: A Pilot Study in Institutionalized Older Adults
Healthcare,
Journal Year:
2024,
Volume and Issue:
12(13), P. 1275 - 1275
Published: June 26, 2024
Institutionalized
older
adults
often
face
complex
medication
regimens,
increasing
their
risk
of
adverse
drug
events
due
to
polypharmacy,
overprescribing,
interactions,
or
the
use
Potentially
Inappropriate
Medications
(PIM).
However,
data
on
and
associated
risks
in
this
population
remain
scarce.
This
pilot
study
aimed
characterize
sociodemographic,
clinical
pharmacotherapeutic
profiles,
PIM
among
institutionalized
elders
residing
Residential
Structures
for
Elderly
People
(ERPI)
Faro
municipality,
located
Portuguese
region
Algarve.
We
conducted
a
cross-sectional
non-randomized
sample
96
participants
(mean
age:
86.6
±
7.86
years)
where
trained
researchers
reviewed
profiles
identified
potentially
inappropriate
medications
using
EU(7)-PIM
list.
Over
90%
exhibited
polypharmacy
(≥5
medications),
with
an
average
9.1
4.15
per
person.
About
92%
had
potential
including
major
moderate
interactions.
More
than
86%
used
at
least
one
medication,
most
commonly
central
nervous
system
drugs.
demonstrates
that
may
be
high
medication-related
problems.
Implementing
comprehensive
review
programs
promoting
adapted
prescribing
practices
are
crucial
optimize
improve
well-being
vulnerable
population.
Language: Английский
Prevalence, Determinants, and Health Outcomes of Potentially Inappropriate Medication Use According to the 2023 Beers Criteria Among Hospitalised Older Patients
Archives of Gerontology and Geriatrics,
Journal Year:
2024,
Volume and Issue:
129, P. 105693 - 105693
Published: Nov. 13, 2024
Language: Английский
Comparing Beers, STOPP and MALPIP criteria in detecting potentially inappropriate medications, clinical outcomes, and cost impacts among older Malaysians: a cohort study
Journal of Pharmaceutical Policy and Practice,
Journal Year:
2024,
Volume and Issue:
17(1)
Published: Dec. 18, 2024
Background:
Potentially
inappropriate
medications
(PIMs)
are
associated
with
adverse
outcomes
and
higher
healthcare
costs
in
older
adults.
Explicit
screening
criteria
like
the
Beers
Criteria,
STOPP
criteria,
Malaysian
Inappropriate
Prescribing
(MALPIP)
served
to
identify
PIMs,
but
comparative
data
scarce.
Aim:
To
evaluate
prevalence
of
PIMs
identified
by
2019,
version
2
MALPIP
adults
examine
their
predictive
ability
for
cost-saving
potential.
Methods:
A
historical
cohort
study
was
conducted
among
aged
≥
60
years
on
five
or
more
four
tertiary
hospitals.
were
using
Beers,
STOPP,
criteria.
Sensitivity,
specificity
abilities
these
analysed
against
clinical
outcomes.
Monthly
cost
savings
calculated
based
hypothetical
deprescribing
scenarios.
Results:
Among
1069
patients,
89.1%
MALPIP,
51.3%
37.0%
moderate
concordance
seen
between
(κ
=
0.437),
lowest
agreement
observed
0.131).
significantly
predicted
hospital
readmissions
(p
0.003),
while
did
not
show
significant
across
all
The
most
common
proton
pump
inhibitors
(PPIs)
nonsteroidal
anti-inflammatory
drugs
(NSAIDs).
Deprescribing
scenarios
indicated
potential
monthly
MYR
4.83
44.84
per
patient,
greatest
Conclusion:
demonstrated
highest
savings,
sensitivity
PIM
detection.
Context-specific
assessments
judgment
crucial
optimising
medication
safety
efficacy
geriatric
pharmacotherapy.
Further
research
is
needed
refine
better
predict
balance
benefits
risks
diverse
settings.
Language: Английский