Immunomodulatory Activity and Inhibitory Effects of Viscum album on Cancer Cells, Its Safety Profiles and Recent Nanotechnology Development DOI
Nermeen Yosri, Nurkhalida Kamal, Ahmed Mediani

et al.

Planta Medica, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 23, 2024

has been employed traditionally to treat various ailments including as add-on therapy for cancer treatment.

Language: Английский

Latest advances in hepatocellular carcinoma management and prevention through advanced technologies DOI Creative Commons

Tamer A. Addissouky,

Ibrahim El Tantawy El Sayed, Majeed M. A. Ali

et al.

Egyptian Liver Journal, Journal Year: 2024, Volume and Issue: 14(1)

Published: Jan. 2, 2024

Abstract Background Hepatocellular carcinoma (HCC) is a common type of liver cancer, with high mortality rate. cancer that can be effectively managed through early detection and accurate diagnosis, followed by personalized treatment plan may include surgical resection, transplantation, minimally-invasive techniques, immunotherapy, or targeted therapy depending on the stage severity cancer. Main body abstract This paper discusses recent advances in detection, management, prevention HCC. The use newer imaging such as Magnetic resonance (MRI) contrast-enhanced ultrasound, along image segmentation technology deep learning models, have greatly enhanced accuracy HCC diagnosis. Minimally-invasive thermal ablation radiofrequency ablation, allowed for more precise destruction tumors, while Nanoparticles, immunotherapy shown promise management advanced Artificial intelligence (AI) machine has revolutionized research, aiding identification high-risk patients predicting outcomes. Lifestyle modifications, weight alcohol avoidance, hepatitis B vaccinations, play critical role preventing development. Short conclusion Recent improving patient therapy, AI research lifestyle modifications prevention. However, further required to fully understand potential benefits nanoparticles, traditional Chinese medicine herbal medicines treatment. Graphical

Language: Английский

Citations

35

Review green synthesis of silver nanoparticles by using plant extracts and their antimicrobial activity DOI Creative Commons
Emad Abada, Abdullah Mashraqi, Yosra Modafer

et al.

Saudi Journal of Biological Sciences, Journal Year: 2023, Volume and Issue: 31(1), P. 103877 - 103877

Published: Nov. 26, 2023

Interest in the biosynthesis of nanoparticles has increased last era by researchers. Nanoparticles have several applications different fields like optoelectronics, magnetic devices, drug delivery, and sensors. Nanoparticle synthesis green methods is safe for environment should be explored encouraged popularly since various plants' high extent to form these nanoparticles. Worldwide, UV spectroscopy, X-ray diffraction, Transmission Electron Microscopy (TEM), Scanning (SEM), Dynamic Light Scattering (DLS), Atomic Force (AFM) besides Fourier Transform Infrared Spectroscopy (FTIR) are used many ways characterize The most advantageous use AgNPs their great attribution as antimicrobial agents. Finally, concept deserved modern technical medical concern. current review shows a complete comprehensive analytical survey with particular focus on activities antimicrobials possible theories effect microbial cell all influenced secondary metabolites.

Language: Английский

Citations

23

Metabolite-driven mechanisms reveal chemical ecology of Lehmann Lovegrass (Eragrostis lehmanniana) invasion in North American semi-arid ecosystems DOI Creative Commons
Ben Yang,

M. K. Crawford,

Taylor A. Portman

et al.

Communications Biology, Journal Year: 2025, Volume and Issue: 8(1)

Published: March 4, 2025

Invasive plants threaten global ecosystems, yet traditional analyses of functional traits cannot fully explain their dominance over co-occurring natives. Metabolomics offers insights into plant invasions, but single-technique studies often miss critical biochemical mechanisms. We employ a multimodal metabolomics approach (¹H NMR, LC MS/MS, FT-ICR-MS, and MALDI-MSI) to investigate the basis Lehmann lovegrass (Eragrostis lehmanniana) invasion in semi-arid North America, comparing it with native grass, Arizona cottontop (Digitaria californica). Our analysis reveals three metabolomic compared cottontop: Enhanced nitrogen allocation shoots, reduced defensive metabolites root layers; increased exudate modulation under stress conditions. These suggest succeeds through adaptation increasing aridity rather than direct competition, demonstrating nutrient-poor environments high phenotypic plasticity response aridity. This integrated provides new mechanistic ecology environmental change.

Language: Английский

Citations

1

Antifungal Activity of Thirty Essential Oils to Control Pathogenic Fungi of Postharvest Decay DOI Creative Commons
Mohamed Béchir Allagui, Marwa Moumni, Gianfranco Romanazzi

et al.

Antibiotics, Journal Year: 2023, Volume and Issue: 13(1), P. 28 - 28

Published: Dec. 28, 2023

Essential oils (EOs) extracted from aromatic or medicinal plants are biodegradable, safe, and regarded as alternatives to chemical pesticides reduce fungal species attacking different crops. In this study, thirty EOs at 0.5 mg/mL were evaluated for in vitro growth inhibition of the main postharvest fungi, which Alternaria alternata, Botrytis cinerea, Penicillium italicum. Cinnamomum verrum EO completely inhibited mycelial A. alternata B. Syzygium aromaticum mycelia alternata. cinerea was by Gautheria fragrantissima, Cymbopogon nardus, Pelargonium asperum, Cupressus sempervirens EOs. G. fragrantissima P. italicum 98%. Overall, displayed highest sensitivity than C. sempervirens, Mentha piperita, Foeniculum vulgare, verrum, S. showed these three pathogens. Minimum inhibitory concentrations lower EOs, ranging between 0.31 0.45 0.37 0.57 mg/mL, respectively, against The tested Further studies needed confirm activities vivo.

Language: Английский

Citations

20

Update on fungal lipid biosynthesis inhibitors as antifungal agents DOI Creative Commons
Monika Vishwakarma, Tanweer Haider, Vandana Soni

et al.

Microbiological Research, Journal Year: 2023, Volume and Issue: 278, P. 127517 - 127517

Published: Oct. 12, 2023

Language: Английский

Citations

17

Aspergillus fumigatus escape mechanisms from its harsh survival environments DOI Open Access
Fangyan Liu, Meng Zeng, Xuedong Zhou

et al.

Applied Microbiology and Biotechnology, Journal Year: 2024, Volume and Issue: 108(1)

Published: Jan. 4, 2024

Language: Английский

Citations

5

The Anti‐Inflammatory Activities of Sphagnum palustre L. Ethanol Extract to Control Inflammation in RAW264.7 Cells DOI Open Access

Zhi Wu,

Jiahui Zheng,

Yang Xu

et al.

Flavour and Fragrance Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

ABSTRACT Discomfort caused by inflammation leads to stress and anxiety in patients seriously decreases the patients' quality of life. People prefer use natural products instead anti‐inflammatory drugs because their low toxicity side effects. Studies have shown that Sphagnum palustre L. ( S. ) can be used as medicinal plant, but few studies focused on its This study explored mechanism action ethanol extract peat moss plant lipopolysaccharide‐induced macrophage RAW264.7 cells. Components extracts (SPE) were identified HPLC‐MS, which mainly included 4‐methoxybenzaldehyde, 4‐methoxycinnamaldehyde oleanolic acid. The effects different concentrations (6.25–100 μg/mL) SPE after 24 h administration evaluated establish a cellular model. Three biological replicates performed based each experiment, MTT assay results showed concentration promoted cell proliferation marked Formazan. In neutral red uptake assay, group was effectively inhibited phagocytosis rate. With increase concentration, intracellular ROS release decreased, detected DCFH‐DA. Immunofluorescence result reactive oxygen species from macrophages with fluorescent markers DAPI. nitric oxide well. What's more, significantly decreased protein expression interleukin (IL)‐1, IL‐6, nuclear factor (NF)‐κB according enzyme‐linked immunosorbent immunocytochemical assays. reduces cells thus is promising plant.

Language: Английский

Citations

0

Phytochemical, Antioxidant and Antidiabetic Activities, In Vitro With In Silico Molecular Docking and Adme/T Studies Of Mistletoe (Viscum Album L.) DOI
Sibel Çelik, Ebru Çöteli

Published: Jan. 1, 2025

Language: Английский

Citations

0

Flavonoids as Natural Anti-Inflammatory Agents in the Atopic Dermatitis Treatment DOI Creative Commons
Nik Khairunissa Nik Abdullah Zawawi, Haslina Ahmad,

Rajesh Madatheri

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(2), P. 261 - 261

Published: Feb. 15, 2025

Eczema is a complex autoimmune condition characterised mainly by inflammation and skin lesions along with physical psychological comorbidities. Although there have been significant advances in understanding the mechanisms behind atopic dermatitis, conventionally available treatments yield inconsistent results some unintended consequences. In today's digital age, where knowledge just click away, natural-based supplements on rise for more "natural" treatment towards any type of disease. Natural compounds, particularly derived from medicinal plants, piqued interest development herbal remedies chronic inflammatory conditions. Among many flavonoids shown promise treating eczema due to their strong anti-inflammatory, antioxidant, anti-allergic properties, making them helpful preventing allergic reactions, inflammation, irritation. This review highlights therapeutic potential flavonoid-based bioactive compounds manage eczema, emphasising action. Additionally, providing comprehensive analysis emerging established while bridging gap between traditional modern medicine. Flavonoids offer variety opportunities further research innovative formulations that can maximise its full benefits. Further combination various approaches such as nanoencapsulation enhanced bioavailability, hydrogel-based delivery systems controlled release, additive manufacturing personalised topical formulations, could align future precision medicine needs.

Language: Английский

Citations

0

Therapeutic potential and limitation of condensed and hydrolyzed tannins in Parkinson's disease DOI
Ran Zhao, Nan Jia, Shuyang Wu

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141814 - 141814

Published: March 1, 2025

Language: Английский

Citations

0