Antibiotics,
Journal Year:
2025,
Volume and Issue:
14(3), P. 308 - 308
Published: March 17, 2025
Background:
The
increased
rates
of
common
fungal
diseases
are
a
constant
challenge.
Therefore,
the
search
for
plant-based
compounds
with
antifungal
activity,
particularly
ones
against
Candida
species,
is
always
relevant
in
medical
context.
However,
most
studies
have
focused
on
screening
activity
extracts
rather
than
isolated
compounds.
Based
this,
we
aimed
to
analyze
and
organize
comprehensive
overview
other
biological
activities
found
Anacardiaceae
family
vegetal
covering
mechanisms
action
potential
therapeutic
applications.
Results:
extracts,
essential
oils,
frequently
assayed
anti-Candida
using
vitro
minimum
inhibitory
concentration
(MIC),
fungicide
(MFC),
halo
inhibition
assays.
albicans,
C.
tropicalis,
parapsilosis,
glabrata,
krusei,
guilliermondii
were
tested
fungus
species.
Essential
oils
used
form
(37%
studies).
included
shikimic
acid,
2-hydroxy-1,8-cineole
β-D-glucopyranoside,
myricitrin,
cardanol,
estragole,
trans-anethole,
β-caryophyllene,
myrcene,
catechin-3-O-rhamnoside,
β-sitosterol-3-O-glucoside,
24Z-isomasticadienolic
oleanolic
pistagremic
apigenin,
sakuranetin,
aldehyde,
integriside.
Conclusions:
Our
data
indicate
that
from
species
show
promise
developing
new
drugs,
mainly
if
consider
their
activities,
including
anti-inflammatory,
antioxidant,
apoptotic
effects.
In
this
context,
they
may
be
candidates
future
treatments
infections,
especially
combination
conventional
antifungals
or
when
nanostructured
formulations,
which
result
avenue
plant
Journal of Fungi,
Journal Year:
2025,
Volume and Issue:
11(4), P. 263 - 263
Published: March 28, 2025
The
citrus
industry
contributes
to
the
cultivation
of
one
most
important
fruit
crops
globally.
However,
trees
are
susceptible
numerous
Bisifusarium,
Fusarium,
and
Neocosmospora-linked
diseases,
with
dry
root
rot
posing
a
serious
threat
orchards
worldwide.
These
infections
exacerbated
by
biotic
abiotic
stresses,
leading
increased
disease
incidence.
Healthy
unexpectedly
wilt
fall,
exhibiting
symptoms
such
as
chlorosis,
dieback,
necrotic
roots,
rot,
wood
discolouration,
eventual
decline.
Research
indicates
that
is
caused
complex
species
from
Nectriaceae
family,
Neocosmospora
solani
being
prominent.
To
improve
treatment
management
strategies,
further
studies
needed
definitively
identify
these
phytopathogens
understand
conditions
factors
associated
Neocosmospora-related
diseases
in
citrus.
This
review
focuses
on
epidemiology
symptomatology
Fusarium
species,
recent
advances
molecular
techniques
for
accurate
phytopathogen
identification,
mechanisms
pathogenicity
resistance
underlying
Neocosmospora-citrus
interactions.
Additionally,
highlights
novel
alternative
methods,
including
biological
control
agents,
promote
environmentally
friendly
sustainable
agricultural
practices.
PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(4), P. e0320682 - e0320682
Published: April 22, 2025
Powdery
mildew
is
a
highly
destructive
disease
that
greatly
reduces
both
the
yield
and
quality
of
wheat.
As
there
limited
research
on
changes
in
microorganism
community
caused
by
powdery
infection
different
tissue
parts,
especially
after
spike
infection,
this
study
aimed
to
examine
surface
microorganisms
infected
healthy
wheat
plants.
Samples
were
collected
from
leaves
spikes,
number
operational
taxonomic
units
(OTUs),
diversity
index,
abundance,
metabolic
microbial
analysed
using
16S
rRNA
amplicon
sequencing
technology.
Through
identification
tissues,
24
phyla
identified
leaves,
20
spikes.
The
dominant
bacterial
observed
Proteobacteria
Bacteroidetes
.
At
genus
level,
19
genera
detected
11
Notably,
total
exceeded
Pseudomonas
,
Sphingomonas
Pantoea
species
37
types
35
included
Pedobacterium
panaciterrae
baetica
rhizophaerae
aerolata
analysis
conducted
revealed
incidence
was
greater
plots
situated
closer
obstacles
than
other
plots.
when
with
mildew,
results
indicated
spikes
significantly
impacted,
response
being
more
pronounced
leaves.
Different
leaf
surface,
pathway
are
mainly
regulation.
These
provide
theoretical
support
for
prevention
control
crops.
Tarım Bilimleri Dergisi,
Journal Year:
2025,
Volume and Issue:
31(2), P. 373 - 391
Published: March 25, 2025
Substances
smaller
than
100
nm
in
size
are
called
nanoparticles.
In
this
study
silver
nanoparticle
synthesis
was
carried
out
by
using
AgNO3
from
leaf,
fruit,
and
branch
aqueous
extracts
of
the
mistletoe
(Viscum
album
ssp.
austriacum)
plant.
It
determined
whether
nanoparticles
were
formed
UV-Vis
method.
As
a
result
analysis
plant
parts,
peaks
observed
at
425,
427,
430
nm,
indicating
surface
plasmon
resonance
AgNPs.
Specific
functional
groups
involved
formation
AgNPs
reduction
Ag
FT-IR
spectroscopy.
SEM
EDS
analyses
that
synthesized
samples
nanosized,
average
59.91.
addition
to
crystallite
calculated
XRD
diffraction,
it
all
obtained
nanometer
range,
same
as
pure
silver.
Considering
antioxidant
results
study,
highest
total
phenolic
flavonoid
amounts
leaf
extract
(35.57±1.39
mg
GAE/g
extract)
fruit
(23.42±1.29
QE),
respectively.
Additionally,
radical
scavenging
activity
sample
(IC50
129.24±1.38
μg/mL).
antidiabetic
(α-amylase
inhibition)
123.59±1.44
result,
these
parts
had
superior
antioxidant,
antidiabetic,
antimicrobial
properties.
Frontiers in Pharmacology,
Journal Year:
2025,
Volume and Issue:
16
Published: May 1, 2025
Aspergillus
flavus
is
an
opportunistic
pathogenic
fungus
that
causes
invasive
aspergillosis
in
humans.
Due
to
the
limited
variety
and
quantity
of
clinical
antifungal
drugs
their
adverse
effects,
development
new
broad-spectrum
urgently
required.
Our
preliminary
research
showed
sodium
houttuyfonate
(SNH)
was
efficacious
against
A.
fumigatus
infection,
but
its
effects
remain
unknown.
In
this
study,
we
used
microdilution
broth
susceptibility
method
determine
activities
four
SNH
12
strains,
vitro
.
To
confirm
therapeutic
effect
on
established
a
mouse
model
pulmonary
(IPA)
with
nasal
drip
method.
All
strains
tested
were
resistant
fluconazole
sensitive
itraconazole,
voriconazole,
amphotericin
B.
The
minimum
inhibitory
concentration
inhibit
growth
90%
cells
(MIC90)
test
64–128
μg/mL.
After
IPA
treated
SNH,
expression
genes
encoding
interleukin
6
(IL-6),
IL-1β,
tumor
necrosis
factor
α
significantly
reduced.
also
reduced
fungal
load
lung,
extent
pathological
damage,
neutrophil/lymphocyte
ratio
blood.
These
findings
indicated
potential
utility
treatment
infections.
Fungal
infections
caused
by
Candida
spp.
are
responsible
for
high
hospital
morbidity
and
mortality
rates.
Therefore,
there
is
a
continuous
search
new
antifungal
medicines,
particularly
ones
with
anti-Candida
activity.
This
review
analyzed
articles
published
between
2002
2023
considering
the
activity
of
chemical
compounds
identified
or
isolated
in
plants
Anacardiaceae
family.
In
addition,
in-silico
prediction
described
was
performed.
The
analysis
35
studies
showed
that
extracts,
essential
oils,
from
were
frequently
determined
vitro
using
minimum
inhibitory
concentration
(MIC).
most
commonly
tested
species
albicans,
C.
tropicalis,
parapsilosis,
glabrata,
krusei,
guilliermondii,
respectively.
Essential
oils
used
form
(37%
studies).
effects
include
cardanol,
estragole,
trans-anethole,
β-caryophyllene,
myrcene,
catechin-3-o-rhamnoside,
β-sitosterol-3-O-glucoside,
24Z-isomasticadienolic
acid,
oleanolic
aldehyde.
evaluation
those
revealed
compounds'
drug-likeness
possible
However,
some
them
toxicity.
conclusion,
family
show
promise
developing
therapeutic
drugs,
especially
combination
conventional
antifungals.
