Malaysian Applied Biology,
Journal Year:
2024,
Volume and Issue:
53(4), P. 139 - 152
Published: Oct. 27, 2024
Plants
are
important
sources
of
underlying
medicinal
value
properties.
The
extraction
bioactive
compounds
from
botanical
using
green
solvents
has
gained
interest
due
to
its
environmental
sustainability.
This
study
highlighted
the
bioactivities
potential
Acmella
paniculata
extract
mediated
by
deep
eutectic
solvent
(DES)
composed
citric
acid
monohydrate
and
glycerol.
paniculata,
a
local
flowering
shrub
was
selected
rich
compounds.
synergistic
effect
between
plant’s
DES
is
capable
enhancing
bioactivity,
making
promising
plant
extractor
candidate.
extracts
were
prepared
in
leaf
flower
parts
centrifugation
method.
phytochemical
screening
for
both
showed
presence
terpenoids
steroid
constituents
which
have
valuable
bioactivity
functions.
antibacterial
activity
assessed
disc
diffusion
assay
exhibited
higher
susceptible
bacterial
response
E.
coli,
Salmonella
enterica
ser.
Typhimurium
S.
aureus
against
compared
extract.
DPPH
conducted
assess
free
radical
scavenging
activity.
demonstrated
(RSA)
75%-77%
while
65%-69%.
results
RSA
emphasizing
as
natural
antioxidant.
anti-inflammatory
determined
egg
albumin
denaturation
assay,
greater
inhibition
rate
than
up
95%
89%
respectively.
Thus,
possess
an
vitro
effect.
Conclusively,
better
DES.
Hence,
offering
new
insight
into
application
effective
alternative
product-based
therapeutics.
ACS Sustainable Chemistry & Engineering,
Journal Year:
2024,
Volume and Issue:
12(46), P. 16934 - 16948
Published: Nov. 2, 2024
The
need
for
low-viscosity
and
sustainable
lubricants
has
always
been
urgent
the
application
of
complex
materials
improvement
machining
accuracy
requirements.
As
a
kind
lubricating
material
with
characteristics
easy
preparation
designable
structure,
deep
eutectic
solvent
(DES)
shows
excellent
performance
controllability
good
potential.
Herein,
series
phosphate
menthol
DESs
(P-DL)
were
designed
prepared
as
high-performance
lubricants.
results
their
physicochemical
properties
show
that
synthesized
exhibit
low
viscosity
superhydrophilicity,
providing
more
efficient
adsorption
interfacial
self-assembly
behavior.
Additionally,
enhanced
corrosion
resistance
thermal
stability
are
conducive
to
chemical
during
shearing.
In
terms
tribological
properties,
P-DL
exhibits
optimal
friction-reducing
antiwear
along
load-bearing
performance.
More
importantly,
lubrication
can
be
obtained
even
under
stringent
diverse
test
conditions,
indicating
universality
great
engineering
potential
these
hydrogen
bond
donors,
longer
alkyl
chains,
suitable
branched
structures
have
positive
effect
concerning
comprehensive
function.
Besides,
synergistic
polar
adsorption,
tribochemical
reaction
is
key
factor
robust
addition,
preparation,
high-performance,
sustainability
all
provide
Meanwhile,
this
chemically
lubricant
optimization
strategy
adjustable
also
provides
theoretical
guidance
development
enrichment
technology.
Antibiotics,
Journal Year:
2024,
Volume and Issue:
13(12), P. 1118 - 1118
Published: Nov. 22, 2024
Background:
Blackcurrant
(Ribes
nigrum
L.)
leaves
are
valuable
sources
of
bioactive
compounds,
including
phenolic
acids,
flavonoids,
and
tannins,
which
contribute
to
their
potent
antioxidant,
anti-inflammatory,
antimicrobial
properties.
Objectives:
The
overall
aim
this
study
was
investigate
the
potential
extracts
rich
in
compounds
from
blackcurrant
prepared
natural
deep
eutectic
solvents
(NaDESs).
objectives
included
optimization
polyphenols
extraction
NaDESs,
characterization
phytochemical
composition
by
liquid
chromatography–mass
spectrometry
(LC-MS),
explanation
chemical
interactions
between
solvent
systems
main
compound
(chlorogenic
acid)
molecular
dynamics
simulations,
evaluation
biological
efficacy
through
tests.
Methods:
Two
hydrogen-bond
acceptors
(HBAs)
three
donors
(HBDs)
were
tested.
experimental
design
variables
such
as
HBA:HBD
molar
ratio,
water
percentage,
time,
techniques
used,
specifically
ultrasound-assisted
(UAE)
ultra-turrax
(UTE).
evaluated
responses
total
polyphenol
content,
flavonoid
antioxidant
activity.
Antimicrobial
assays
performed
on
four
Gram-positive
Gram-negative
bacterial
species,
well
one
fungus,
Candida
albicans.
Results:
obtained
UAE
showed
higher
concentrations
increased
potential.
LC-MS
analysis
revealed
predominant
presence
chlorogenic
acid.
significant
activities
against
bacteria
Conclusions:
This
highlights
potentials
confirming
that
type
enhances
offers
perspectives
for
new
therapeutic
formulations.
Malaysian Applied Biology,
Journal Year:
2024,
Volume and Issue:
53(4), P. 139 - 152
Published: Oct. 27, 2024
Plants
are
important
sources
of
underlying
medicinal
value
properties.
The
extraction
bioactive
compounds
from
botanical
using
green
solvents
has
gained
interest
due
to
its
environmental
sustainability.
This
study
highlighted
the
bioactivities
potential
Acmella
paniculata
extract
mediated
by
deep
eutectic
solvent
(DES)
composed
citric
acid
monohydrate
and
glycerol.
paniculata,
a
local
flowering
shrub
was
selected
rich
compounds.
synergistic
effect
between
plant’s
DES
is
capable
enhancing
bioactivity,
making
promising
plant
extractor
candidate.
extracts
were
prepared
in
leaf
flower
parts
centrifugation
method.
phytochemical
screening
for
both
showed
presence
terpenoids
steroid
constituents
which
have
valuable
bioactivity
functions.
antibacterial
activity
assessed
disc
diffusion
assay
exhibited
higher
susceptible
bacterial
response
E.
coli,
Salmonella
enterica
ser.
Typhimurium
S.
aureus
against
compared
extract.
DPPH
conducted
assess
free
radical
scavenging
activity.
demonstrated
(RSA)
75%-77%
while
65%-69%.
results
RSA
emphasizing
as
natural
antioxidant.
anti-inflammatory
determined
egg
albumin
denaturation
assay,
greater
inhibition
rate
than
up
95%
89%
respectively.
Thus,
possess
an
vitro
effect.
Conclusively,
better
DES.
Hence,
offering
new
insight
into
application
effective
alternative
product-based
therapeutics.
