Ancient materials for new applications: The combination of montmorillonite with polysaccharides for biomedical uses

Applied Clay Science, Journal Year: 2025, Volume and Issue: 266, P. 107688 - 107688

Published: Jan. 5, 2025

Language: Английский

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Structural and electrochemical properties of NH ₄ SCN-doped almond gum biopolymer electrolytes

International Journal of Polymer Analysis and Characterization, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 14

Published: Jan. 10, 2025

The development of solid polymer electrolytes based on natural gums represents a promising step toward sustainable energy solutions, driven by their abundance, cost-effectiveness, biodegradability, and nontoxic nature. This study primarily focused the fabrication electrolyte using almond gum (Amygdalus communis) doped with NH4SCN salt solution casting method investigated its impact ionic conductivity. An conductivity 1.123 × 10−4 Scm−1 was attained for membrane 40 wt% ammonium thiocyanate. Through XRD FTIR analysis, amorphous nature interaction certain functional groups provided insights into potential use in systems. Transference number analysis confirmed major charge carriers present electrolyte.

Language: Английский

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Therapeutic Prospects of Undaria pinnatifida Polysaccharides: Extraction, Purification, and Functional Activity

Marine Drugs, Journal Year: 2025, Volume and Issue: 23(4), P. 163 - 163

Published: April 8, 2025

Undaria pinnatifida, an edible brown seaweed that is widely consumed in East Asia, has gained increasing recognition for its health benefits. Among bioactive compounds, polysaccharides have attracted significant attention due to their diverse biological activity. This review provides a comprehensive overview of recent advancements the extraction, purification, structural characterization, and bioactivity U. pinnatifida polysaccharides. We discuss state-of-the-art extraction techniques, including ultrasound-assisted, microwave-assisted, enzyme-assisted as well purification strategies such membrane separation chromatographic methods. Furthermore, we highlight potential activity, antioxidant, immunomodulatory, anticancer, gut health-promoting, anti-hyperglycemic effects, along with underlying mechanisms action. By summarizing latest research, this aims provide valuable insights into development application functional foods pharmaceuticals.

Language: Английский

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‘As of my last knowledge update’: How is content generated by ChatGPT infiltrating scientific papers published in premier journals?

Learned Publishing, Journal Year: 2024, Volume and Issue: 38(1)

Published: Dec. 24, 2024

Abstract The aim of this paper is to highlight the situation whereby content generated by large language model ChatGPT appearing in peer‐reviewed papers journals recognized publishers. demonstrates how identify sections that indicate a text fragment was generated, is, entirely created, ChatGPT. To prepare an illustrative compilation appear indexed Web Science and Scopus databases possessing Impact Factor CiteScore indicators, SPAR4SLR method used, which mainly applied systematic literature reviews. Three main findings are presented: highly regarded premier journals, articles bear hallmarks AI models, whose use not declared authors (1); many these identified already receiving citations from other scientific works, also placed found (2); and, most belong disciplines medicine computer science, but there such as environmental engineering, sociology, education, economics management (3). This aims continue add recently initiated discussion on models like creation scholarly works.

Language: Английский

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Exploring the Biosynthesis, Production, and Functional Properties of Bacterial Cellulose

Advances in Science, Technology & Innovation/Advances in science, technology & innovation, Journal Year: 2025, Volume and Issue: unknown, P. 29 - 39

Published: Jan. 1, 2025

Language: Английский

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Chondroitin Sulfate/Cyanocobalamin–Chitosan Polyelectrolyte Complexes for Improved Oral Delivery of Colistin

Polysaccharides, Journal Year: 2025, Volume and Issue: 6(1), P. 21 - 21

Published: March 7, 2025

Introduction. The rise of multidrug resistance in Gram-negative ESKAPE pathogens is a critical challenge for modern healthcare. Colistin (CT), peptide antibiotic, remains last-resort treatment infections caused by these superbugs due to its potent activity against bacteria and the rarity resistance. However, clinical use severely limited high nephro- neurotoxicity, low oral bioavailability, other adverse effects. A promising strategy improve biopharmaceutical properties safety profile antibiotics development biopolymer-based delivery systems, also known as nanoantibiotics. Objective. aim this study was develop polyelectrolyte complexes (PECs) CT overcome major limitations, such poor bioavailability toxicity. Methods. PECs were formulated using chondroitin sulfate (CHS) cyanocobalamin–chitosan conjugate (CSB12). Vitamin B12 incorporated targeting ligand enhance intestinal permeability through receptor-mediated transport. resulting (CHS-CT-CSB12) characterized particle size, ζ-potential, encapsulation efficiency, drug release under simulated gastrointestinal conditions (pH 1.6, 6.5, 7.4). antimicrobial encapsulated evaluated vitro Pseudomonas aeruginosa. Results. CHS-CT-CSB12 exhibited hydrodynamic diameter 446 nm ζ-potential +28.2 mV. efficiency reached 100% at loading 200 µg/mg. In studies showed that approximately 70% released within 1 h pH 1.6 (simulating gastric conditions), while cumulative 80% over 6 observed 6.5 7.4 conditions). This suggests potential enteric-coated capsules or specific administration guidelines, taking on an empty stomach with plenty water. P. aeruginosa comparable free drug, minimum inhibitory concentration µg/mL both. inclusion vitamin significantly improved permeability, evidenced apparent coefficient (Papp) 1.1 × 10−6 cm/s CT. Discussion. developed offer several advantages conventional formulations. enhances absorption across barrier, potentially increasing bioavailability. addition, controlled environment reduces risk systemic toxicity, particularly neurotoxicity. These findings highlight nanotechnology-based platform improving challenging antibiotics. Conclusions. demonstrates innovative system addresses limitations improves therapeutic efficacy. Future work will focus vivo evaluation efficacy system, well exploring applicability similar challenges.

Language: Английский

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Alginate supramolecular for encapsulation of plant biocontrol bacteria: A review

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123511 - 123511

Published: March 1, 2025

Language: Английский

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Recent Trends and Future Directions in 3D Printing of Biocompatible Polymers

Journal of Manufacturing and Materials Processing, Journal Year: 2025, Volume and Issue: 9(4), P. 129 - 129

Published: April 14, 2025

Three-dimensional (3D) bioprinting using biocompatible polymers has emerged as a revolutionary technique in tissue engineering and regenerative medicine. These biopolymers mimic the extracellular matrix (ECM) enhance cellular behavior. The current review presents recent advancements additive manufacturing processes including Stereolithography (SLA), Fused Filament Fabrication (FFF), Selective Laser Sintering (SLS), inkjet printing. It also explores fundamentals of 3D printing properties for bioprinting. By mixing biopolymers, enhancing rheological characteristics, adding bioactive components, further have been made organ transplantation, drug development, engineering. As research progresses, potential to fundamentally transform healthcare system is becoming obvious clear. However, therapeutic printed structures hindered by issues such material anisotropy, poor mechanical properties, need more biodegradable architectures. Future should concentrate on optimizing process sophisticated computational techniques, systematically examining characteristics customizing bioinks different cell types, exploring sustainable materials.

Language: Английский

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The anti-angiogenic, anti-inflammatory, and anticoagulant potential of a polysaccharide extracted from the brown alga Cystoseira humilis

European Polymer Journal, Journal Year: 2024, Volume and Issue: unknown, P. 113461 - 113461

Published: Sept. 1, 2024

Language: Английский

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Chitin and Its Derivative Chitosan: Distribution in Nature, Applications Realm, and Technology Research (A Review)

International journal of medicinal mushrooms, Journal Year: 2024, Volume and Issue: 26(10), P. 69 - 81

Published: Jan. 1, 2024

The present review highlights the chitin/chitosan as biopolymers that are promising for biomedical research development. Our goal was to assess potential practical use of these and summarize information on traditional innovative technologies their production purification. widespread occurrence chitin chitosan in nature well unique chemical biological properties reasons growing interest latter several pharmaceutical fields. main stages extraction its further modification into deproteinization, demineralization, deacetylation, methods purification filtration, dialysis reprecipitation. profitability from crustaceans edible mushrooms is approximately at same level. cost mushroom products can be reduced by using agricultural or forestry waste nutrient substrates. This makes fungi sources forested regions a rather issue.

Language: Английский

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