An overview of betulin: botanical source, derivatives and biological potential: Mini Review

Journal of Experimental Biology and Agricultural Sciences, Journal Year: 2025, Volume and Issue: 13(1), P. 11 - 28

Published: March 5, 2025

This review aims to provide insight into and summarize the potential of betulin its derivatives as important pharmaceutical molecules, including their underlying mechanisms action. investigation compiles comprehensive scientific data regarding a botanical raw material for industrial applications. Betulin, natural pentacyclic lupane-triterpenoid, exhibits diverse biological activities, addressing metabolic dysfunctions, infectious diseases, cardiovascular disorders, carcinogenic activity. The extraction from sources, mainly birch bark, is relatively simple cost-effective, making it an attractive compound cosmetic industries. study lists 93 plant sources explores repurposing effective therapeutic agent. It highlights antiviral, anti-inflammatory, anticancer, hepatoprotective compound, emphasizing benefits derivatizing with various groups or moieties, such imidazole carboxylic ester, hemisuccinate, hemiphthalate, nicotinate, acetylbetulin-28-o-triphenylphosphonium, succinyl, 3-substituted glutaryl. information gathered comes databases, Google Scholar, PubMed, ethnobotanical references, classical texts.

Language: Английский

PavSPLs are key regulators of growth, development, and stress response in sweet cherry

Plant Science, Journal Year: 2024, Volume and Issue: 350, P. 112279 - 112279

Published: Oct. 12, 2024

Language: Английский