Nutrition,
Journal Year:
2023,
Volume and Issue:
112, P. 112077 - 112077
Published: May 10, 2023
Sarcopenia
has
been
identified
as
a
prognostic
factor
among
certain
types
of
cancer.
However,
it
is
unclear
whether
there
value
temporalis
muscle
thickness
(TMT),
potential
surrogate
for
sarcopenia,
in
adults
patients
with
brain
tumors.
Therefore,
we
searched
the
Medline,
Embase,
and
PubMed
to
systematically
review
meta-analyze
relationship
between
TMT
overall
survival,
progression-free
complications
tumors
hazard
ratio
(HR)
or
odds
ratios
(OR),
95%
confidence
interval
(CI)
were
evaluated.
The
quality
studies
(QUIPS)
instrument
was
employed
evaluate
study
quality.
Nineteen
involving
4570
included
qualitative
quantitative
analysis.
Meta-analysis
revealed
thinner
associated
poor
survival
(HR,
1.72;
CI,
1.45–2.04;
P
<
0.01)
Sub-analyses
showed
that
association
existed
both
primary
2.02;
1.55-2.63)
metastases
1.39;
1.30-1.49).
Moreover,
also
independent
predictor
2.88;
1.85–4.46;
0.01).
improve
clinical
decision
making
important
integrate
assessment
into
routine
settings
Surgical Neurology International,
Journal Year:
2021,
Volume and Issue:
12, P. 67 - 67
Published: Feb. 23, 2021
Background:
Skeletal
muscle
mass
is
an
important
factor
for
various
diseases’
outcomes.
The
psoas
cross-sectional
area
on
the
abdominal
computed
tomography
(CT),
gait
speed,
and
handgrip
strength
used
to
measure
it.
However,
it
difficult
neurological
patients’
or
function
because
(1)
we
do
not
perform
CT.
(2)
Such
patients
have
impaired
consciousness,
disturbance,
paresis,
need
of
rest.
Temporal
thickness
(TMT)
magnetic
resonance
imaging
(MRI)
now
attractive
skeletal
volume
indicator,
but
reference
values
are
established.
We
herein
investigated
standard
value
Japanese
TMT
using
brain
check-up
database
by
MRI.
Methods:
retrospectively
360
individuals
from
two
institutions
between
2017
2019.
measured
T1-weighted
images
in
previously
reported
way.
associations
other
variables
were
analyzed.
Results:
214
women
146
men,
ranging
35
84
years
old,
was
investigated.
ranged
3.69
16.90
mm.
Mean
significantly
higher
men
compared
except
over
70-year-old
cohort.
correlated
weight
body
index
both
sexes.
Conclusion:
This
first
retrospective
study
database.
Our
results
just
values,
these
would
be
useful
further
investigation
neurosurgical
diseases
regarding
sarcopenia.
Cancer Management and Research,
Journal Year:
2021,
Volume and Issue:
Volume 13, P. 6621 - 6632
Published: Aug. 1, 2021
Temporal
muscle
thickness
(TMT)
has
been
proposed
as
a
novel
surrogate
marker
for
skeletal
mass
in
head
and
neck
malignancies.
This
study
investigated
the
TMT
prognostic
relevance
with
gliomas
evaluated
influence
of
values
on
survival
patients
different
grades
IDH
subtypes.The
patients'
was
measured
contrast-enhanced
T1-weighted
magnetic
resonance
images
before
surgical
treatment.
Patients
were
divided
into
two
cohorts
based
their
median
values.
The
Kaplan-Meier
curve
used
to
compute
overall
(OS)
categories
all
gliomas.
Univariate
multivariate
Cox
regression
analyses
conducted
assess
association
between
OS
TMT,
hematological
markers,
other
clinical
factors
glioma
patients.
Moreover,
diagnostic
efficiency
single
combination
biomarkers
using
receiver
operating
characteristic
analysis.We
retrospectively
analyzed
261
newly
diagnosed
November
2016
May
2020
at
Hunan
Cancer
Hospital.
analysis
indicated
that
higher
(HR
0.286,
P<
0.001)
KPS
score
0.629,
P=
0.012)
protective
wildtype
status
2.946,
0.001),
RDW
>
12.6
1.513,
0.036),
NLR
4
1.560,
0.042)
poor
Subsequently,
thicker
found
have
significantly
better
(P<0.001)
than
thinner
among
WHO
III
IV
grade
or
without
mutation.
considered
biomarker
recently
prevalent
predicting
high-grade
[0.856
(0.797-0.916)]
IDH-
wild-type
[0.864
(0.786-0.941)]
gliomas.This
suggests
is
positive
prognosis
greater
subtypes.
The Journals of Gerontology Series A,
Journal Year:
2021,
Volume and Issue:
76(12), P. 2242 - 2248
Published: March 23, 2021
To
investigate
the
relationship
between
temporalis
muscle
thickness
(TMT)
at
baseline
as
a
surrogate
marker
for
sarcopenia
and
long-term
motor
outcomes
in
patients
with
Parkinson's
disease
(PD).We
enrolled
249
drug-naïve
early-stage
PD
(119
males
130
females,
follow-up
>
3
years).
Baseline
TMT
of
each
patient
was
measured
on
axial
plane
T1-weighted
images.
The
association
assessed
using
Cox
regression
models
levodopa-induced
dyskinesia,
wearing-off,
freezing
gait
linear
mixed
model
longitudinal
increases
levodopa-equivalent
dose
per
body
weight
over
time.
Statistical
analyses
were
performed
separately
sex
if
an
interaction
effect
assumed.TMT
differed
substantially
sexes,
male
had
higher
(6.69
±
1.39
mm)
than
female
(5.64
1.34
mm,
p
<
.001).
demonstrated
that
not
associated
risk
developing
or
during
period.
applied
slower
patients,
but
patients.This
study
could
be
indicator
requirement
dopaminergic
medications
PD,
suggesting
may
have
detrimental
progression
sex-specific
manner.
Clinical and Translational Radiation Oncology,
Journal Year:
2023,
Volume and Issue:
40, P. 100621 - 100621
Published: March 27, 2023
Glioblastoma
(GBM)
patients
face
a
strongly
unfavorable
prognosis
despite
multimodal
therapy
regimens.
However,
individualized
mortality
prediction
remains
imprecise.
Harnessing
routine
radiation
planning
cranial
computed
tomography
(CT)
scans,
we
assessed
cervical
body
composition
measures
as
novel
biomarkers
for
overall
survival
(OS)
in
GBM
patients.We
performed
threshold-based
semi-automated
quantification
of
muscle
and
subcutaneous
fat
cross-sectional
area
(CSA)
at
the
levels
first
second
vertebral
body.
First,
tested
this
method's
validity
by
correlating
to
established
abdominal
an
open-source
whole-body
CT
cohort.
We
then
identified
consecutive
undergoing
recent
diagnosis
our
institution
from
2010
2020
quantified
on
scans.
Finally,
univariable
multivariable
time-to-event
analyses,
adjusting
age,
sex,
mass
index,
comorbidities,
performance
status,
extent
surgical
resection,
tumor
diagnosis,
MGMT
methylation.Cervical
measurements
were
well-correlated
with
markers
(Spearman's
rho
greater
than
0.68
all
cases).
Subsequently,
included
324
study
cohort
(median
age
63
years,
60.8%
male).
293
(90.4%)
died
during
follow-up.
Median
time
was
13
months.
Patients
below-average
CSA
or
above-average
demonstrated
shorter
survival.
In
continuous
remained
independently
associated
OS.This
exploratory
establishes
routinely
available
scans
confirms
their
association
OS
diagnosed
GBM.
Nutrition,
Journal Year:
2023,
Volume and Issue:
112, P. 112077 - 112077
Published: May 10, 2023
Sarcopenia
has
been
identified
as
a
prognostic
factor
among
certain
types
of
cancer.
However,
it
is
unclear
whether
there
value
temporalis
muscle
thickness
(TMT),
potential
surrogate
for
sarcopenia,
in
adults
patients
with
brain
tumors.
Therefore,
we
searched
the
Medline,
Embase,
and
PubMed
to
systematically
review
meta-analyze
relationship
between
TMT
overall
survival,
progression-free
complications
tumors
hazard
ratio
(HR)
or
odds
ratios
(OR),
95%
confidence
interval
(CI)
were
evaluated.
The
quality
studies
(QUIPS)
instrument
was
employed
evaluate
study
quality.
Nineteen
involving
4570
included
qualitative
quantitative
analysis.
Meta-analysis
revealed
thinner
associated
poor
survival
(HR,
1.72;
CI,
1.45–2.04;
P
<
0.01)
Sub-analyses
showed
that
association
existed
both
primary
2.02;
1.55-2.63)
metastases
1.39;
1.30-1.49).
Moreover,
also
independent
predictor
2.88;
1.85–4.46;
0.01).
improve
clinical
decision
making
important
integrate
assessment
into
routine
settings
