Neuroradiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 24, 2025
In
primary
central
nervous
system
lymphoma
(PCNSL),
B-cell
lymphoma-6
(BCL-6)
is
an
unfavorable
prognostic
biomarker.
We
aim
to
non-invasively
detect
BCL-6
overexpression
in
PCNSL
patients
using
multiparametric
MRI
and
machine
learning
techniques.
65
(101
lesions)
with
(PCNSL)
diagnosed
from
January
2013
July
2023,
all
were
randomly
divided
into
a
training
set
validation
according
ratio
of
8
2.
ADC
map
derived
DWI
(b
=
0/1000
s/mm2),
fast
spin
echo
T2WI,
T2FLAIR,
collected
at
3.0
T.
A
total
2234
radiomics
features
the
tumor
segmentation
area
extracted
LASSO
used
select
features.
Logistic
regression
(LR),
Naive
bayes
(NB),
Support
vector
(SVM),
K-nearest
Neighbor,
(KNN)
Multilayer
Perceptron
(MLP),
for
learning,
sensitivity,
specificity,
accuracy
F1-score,
under
curve
(AUC)
was
evaluate
detection
performance
five
classifiers,
6
groups
combinations
different
sequences
fitted
5
optimal
classifier
obtained.
status
could
be
identified
varying
degrees
30
models
based
on
radiomics,
model
improved
by
combining
classifiers.
(SVM)
combined
three
sequence
group
had
largest
AUC
(0.95)
satisfactory
(0.87)
set.
Multiparametric
promising
detecting
overexpression.
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
1(1)
Published: Jan. 1, 2024
Abstract
The
advent
of
radiomics
has
revolutionized
medical
image
analysis,
affording
the
extraction
high
dimensional
quantitative
data
for
detailed
examination
normal
and
abnormal
tissues.
Artificial
intelligence
(AI)
can
be
used
enhancement
a
series
steps
in
pipeline,
from
acquisition
preprocessing,
to
segmentation,
feature
extraction,
selection,
model
development.
aim
this
review
is
present
most
AI
methods
explaining
advantages
limitations
methods.
Some
prominent
architectures
mentioned
include
Boruta,
random
forests,
gradient
boosting,
generative
adversarial
networks,
convolutional
neural
transformers.
Employing
these
models
process
analysis
significantly
enhance
quality
effectiveness
while
addressing
several
that
reduce
predictions.
Addressing
enable
clinical
decisions
wider
adoption.
Importantly,
will
highlight
how
assist
overcoming
major
bottlenecks
implementation,
ultimately
improving
translation
potential
method.
Frontiers of Medicine,
Journal Year:
2024,
Volume and Issue:
18(5), P. 778 - 797
Published: Aug. 8, 2024
Abstract
Cancer
is
a
heterogeneous
and
multifaceted
disease
with
significant
global
footprint.
Despite
substantial
technological
advancements
for
battling
cancer,
early
diagnosis
selection
of
effective
treatment
remains
challenge.
With
the
convenience
large-scale
datasets
including
multiple
levels
data,
new
bioinformatic
tools
are
needed
to
transform
this
wealth
information
into
clinically
useful
decision-support
tools.
In
field,
artificial
intelligence
(AI)
technologies
their
highly
diverse
applications
rapidly
gaining
ground.
Machine
learning
methods,
such
as
Bayesian
networks,
support
vector
machines,
decision
trees,
random
forests,
gradient
boosting,
K-nearest
neighbors,
neural
network
models
like
deep
learning,
have
proven
valuable
in
predictive,
prognostic,
diagnostic
studies.
Researchers
recently
employed
large
language
tackle
dimensions
problems.
However,
leveraging
opportunity
utilize
AI
clinical
settings
will
require
surpassing
obstacles—a
major
issue
lack
use
available
reporting
guidelines
obstructing
reproducibility
published
review,
we
discuss
methods
explore
benefits
limitations.
We
summarize
healthcare
highlight
potential
role
impact
on
future
directions
cancer
research.
Cancers,
Journal Year:
2021,
Volume and Issue:
13(21), P. 5547 - 5547
Published: Nov. 5, 2021
Radiomics
is
a
developing
new
discipline
that
analyzes
conventional
medical
images
to
extract
quantifiable
data
can
be
mined
for
biomarkers
show
the
biology
of
pathological
processes
at
microscopic
levels.
These
converted
into
image-based
signatures
improve
diagnostic,
prognostic
and
predictive
accuracy
in
cancer
patients.
The
combination
radiomics
molecular
data,
called
radiogenomics,
has
clear
implications
patients’
management.
Though
some
studies
have
focused
on
radiogenomics
hepatocellular
carcinoma
patients,
only
few
examined
colorectal
metastatic
lesions
liver.
Moreover,
need
differentiate
between
liver
fundamental
accurate
diagnosis
treatment.
In
this
review,
we
summarize
knowledge
gained
from
hepatic
patients
their
use
early
diagnosis,
response
assessment
treatment
decisions.
We
also
investigate
value
as
possible
biomarkers.
addition,
great
potential
image
mining
provide
comprehensive
view
niche
formation
thoroughly.
Finally,
challenges
current
limitations
detection
premetastatic
niche,
based
are
discussed.
Physics in Medicine and Biology,
Journal Year:
2023,
Volume and Issue:
68(23), P. 23TR01 - 23TR01
Published: Sept. 18, 2023
Breast
cancer,
which
is
the
most
common
type
of
malignant
tumor
among
humans,
a
leading
cause
death
in
females.
Standard
treatment
strategies,
including
neoadjuvant
chemotherapy,
surgery,
postoperative
targeted
therapy,
endocrine
and
radiotherapy,
are
tailored
for
individual
patients.
Such
personalized
therapies
have
tremendously
reduced
threat
breast
cancer
Furthermore,
early
imaging
screening
plays
an
important
role
reducing
cycle
improving
prognosis.
The
recent
innovative
revolution
artificial
intelligence
(AI)
has
aided
radiologists
accurate
diagnosis
cancer.
In
this
review,
we
introduce
necessity
incorporating
AI
into
applications
mammography,
ultrasonography,
magnetic
resonance
imaging,
positron
emission
tomography/computed
tomography
based
on
published
articles
since
1994.
Moreover,
challenges
discussed.
Neuroradiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 24, 2025
In
primary
central
nervous
system
lymphoma
(PCNSL),
B-cell
lymphoma-6
(BCL-6)
is
an
unfavorable
prognostic
biomarker.
We
aim
to
non-invasively
detect
BCL-6
overexpression
in
PCNSL
patients
using
multiparametric
MRI
and
machine
learning
techniques.
65
(101
lesions)
with
(PCNSL)
diagnosed
from
January
2013
July
2023,
all
were
randomly
divided
into
a
training
set
validation
according
ratio
of
8
2.
ADC
map
derived
DWI
(b
=
0/1000
s/mm2),
fast
spin
echo
T2WI,
T2FLAIR,
collected
at
3.0
T.
A
total
2234
radiomics
features
the
tumor
segmentation
area
extracted
LASSO
used
select
features.
Logistic
regression
(LR),
Naive
bayes
(NB),
Support
vector
(SVM),
K-nearest
Neighbor,
(KNN)
Multilayer
Perceptron
(MLP),
for
learning,
sensitivity,
specificity,
accuracy
F1-score,
under
curve
(AUC)
was
evaluate
detection
performance
five
classifiers,
6
groups
combinations
different
sequences
fitted
5
optimal
classifier
obtained.
status
could
be
identified
varying
degrees
30
models
based
on
radiomics,
model
improved
by
combining
classifiers.
(SVM)
combined
three
sequence
group
had
largest
AUC
(0.95)
satisfactory
(0.87)
set.
Multiparametric
promising
detecting
overexpression.