Scaptotrigona mexicana Propolis from Totonacapan Region: Chemical Composition, Antioxidant and Antibacterial Activities DOI Creative Commons
Blanca Rivero-Cruz,

Maria Ema Rojas-Brandao,

Adriana Correa-Benítez

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(6), P. 1370 - 1370

Published: March 19, 2025

The propolis produced by stingless bees is a complex mixture of natural sticky components mixed with soil or clay. Global research on has focused studying the biological and pharmacological properties chemical composition bee from Brazil, Indonesia, other regions. However, studies in Mexico are scarce. This study aimed to determine geopropolis Scaptotrigona mexicana collected Totonacapan region evaluate its antioxidant antibacterial activities. phenolic contents ethanolic extract ranged 2.45 ± 0.03 mg GAE/g 3.48 0.56 dry extract. total flavonoid content 0.69 QE/g 0.84 0.009 activity extracts was assessed via DPPH, ABTS, FRAP assays. minimum inhibitory concentration values exhibited (>512 g/mL) for Gram-negative bacteria (Pseudomonas aerugunosa Phorphyromonas gingivalis) were higher than those Gram-positive bacteria. showed highest against Streptococcus mutans (256 g/mL). Five known compounds, taraxeryl acetate (1), lupeol (3), cicloart-23-en-3β,25-diol (5), mangiferoic acid (6), 5-(11’Z-heptadecenyl)-resorcinol (7), two irresoluble mixtures 3-O-acetyl-α-(2a) 3-O-acetyl-β-amyrins (2b), α- (4a) -amyrins (4b), identified nuclear magnetic resonance spectroscopy mass spectrometry. Additionally, 39 volatile compounds headspace-solid phase microextraction using hyphenated gas chromatography coupled spectrometry time-of-flight. main detected include trans-α-bergamotene (8.15%), hexanal (7.17%), 2-heptanone (7.60%), α-copaene (7.09%).

Language: Английский

Physiological and behavioral effects of titanium dioxide nanoparticle exposure on stingless bee foragers DOI
Thaís Andrade Viana, Tandara Ketlyn Degobi Xavier, Wagner Faria Barbosa

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 488, P. 137315 - 137315

Published: Jan. 22, 2025

Language: Английский

Citations

0
Effects of the insecticide thiodicarb on non-target organs and behavior of the stingless bee Partamona helleri (Hymenoptera: Meliponini) DOI

Davy Soares Gomes,

Franciane Rosa Miranda, João Victor de Oliveira Motta

et al.

Pesticide Biochemistry and Physiology, Journal Year: 2025, Volume and Issue: unknown, P. 106308 - 106308

Published: Jan. 1, 2025

Language: Английский

Citations

0
Characterization of Axestotrigona ferruginea and Apis mellifera honeys from different geographical origins DOI
Christopher Alphonce Mduda, Isack Frank Rikohe, Juma Mahmud Hussein

et al.

Food and Humanity, Journal Year: 2025, Volume and Issue: 4, P. 100516 - 100516

Published: Jan. 27, 2025

Language: Английский

Citations

0
Meliponini Geopropolis Extracts Induce ROS Production and Death in Leishmania amazonensis Promastigotes and Axenic Amastigotes In Vitro DOI Creative Commons

Kamila M. Sette,

Andreza R. Garcia, Luzineide W. Tinoco

et al.

Biology, Journal Year: 2025, Volume and Issue: 14(2), P. 162 - 162

Published: Feb. 6, 2025

Leishmania amazonensis, a cause of cutaneous leishmaniasis in Brazil, is neglected disease with toxic and inconsistently effective treatments. The parasite’s survival depends on managing oxidative stress, making redox-regulating enzymes potential therapeutic targets. Geopropolis, resinous product from native stingless bees, shows promising antiparasitic effects. This study aims to evaluate the anti-L. amazonensis activity geopropolis produced by Melipona bicolor, M. marginara, mondury, quadrifasciata (two samples), targeting responsible for redox balance. Ethanol extracts each bee (BCRL, MRGT, MNDY, MNDA(1), MNDA(2), respectively) were analyzed total phenolics flavonoids. Promastigotes axenic amastigotes treated various extract concentrations, parasite viability was assessed using resazurin reduction method. Cytotoxicity tested peritoneal macrophages, RAW 264.7, VERO cell lines (MTT assay), erythrocytes (hemolysis assay). Additionally, mitochondrial dehydrogenase activity, reactive oxygen species (ROS) production, inhibition recombinant arginase, autophagic also evaluated parasites. MRGT showed highest levels (762 mg GAE/g) flavonoids (345 QE/g). MDRY more against promastigote amastigote forms (IC50 = 168 19.7 µg/mL, respectively). lower cytotoxicity 264.7 (CC50 654 µg/mL 981 Erythrocytes exhibited reduced sensitivity MNDA(2) (HC50 710 µg/mL). dehydrogenases LiARG treating parasites following induction ROS activity. These results highlight as source substances capable inducing stress parasite.

Language: Английский

Citations

0
Scaptotrigona mexicana Propolis from Totonacapan Region: Chemical Composition, Antioxidant and Antibacterial Activities DOI Creative Commons
Blanca Rivero-Cruz,

Maria Ema Rojas-Brandao,

Adriana Correa-Benítez

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(6), P. 1370 - 1370

Published: March 19, 2025

The propolis produced by stingless bees is a complex mixture of natural sticky components mixed with soil or clay. Global research on has focused studying the biological and pharmacological properties chemical composition bee from Brazil, Indonesia, other regions. However, studies in Mexico are scarce. This study aimed to determine geopropolis Scaptotrigona mexicana collected Totonacapan region evaluate its antioxidant antibacterial activities. phenolic contents ethanolic extract ranged 2.45 ± 0.03 mg GAE/g 3.48 0.56 dry extract. total flavonoid content 0.69 QE/g 0.84 0.009 activity extracts was assessed via DPPH, ABTS, FRAP assays. minimum inhibitory concentration values exhibited (>512 g/mL) for Gram-negative bacteria (Pseudomonas aerugunosa Phorphyromonas gingivalis) were higher than those Gram-positive bacteria. showed highest against Streptococcus mutans (256 g/mL). Five known compounds, taraxeryl acetate (1), lupeol (3), cicloart-23-en-3β,25-diol (5), mangiferoic acid (6), 5-(11’Z-heptadecenyl)-resorcinol (7), two irresoluble mixtures 3-O-acetyl-α-(2a) 3-O-acetyl-β-amyrins (2b), α- (4a) -amyrins (4b), identified nuclear magnetic resonance spectroscopy mass spectrometry. Additionally, 39 volatile compounds headspace-solid phase microextraction using hyphenated gas chromatography coupled spectrometry time-of-flight. main detected include trans-α-bergamotene (8.15%), hexanal (7.17%), 2-heptanone (7.60%), α-copaene (7.09%).

Language: Английский

Citations

0