Displacement experiments provide evidence for path integration in Drosophila
Journal of Experimental Biology,
Journal Year:
2023,
Volume and Issue:
226(12)
Published: May 25, 2023
Like
many
other
animals,
insects
are
capable
of
returning
to
previously
visited
locations
using
path
integration,
which
is
a
memory
travelled
direction
and
distance.
Recent
studies
suggest
that
Drosophila
can
also
use
integration
return
food
reward.
However,
the
existing
experimental
evidence
for
in
has
potential
confound:
pheromones
deposited
at
site
reward
might
enable
flies
find
rewarding
even
without
memory.
Here,
we
show
indeed
cause
naïve
accumulate
where
previous
had
been
rewarded
navigation
task.
Therefore,
designed
an
experiment
determine
if
despite
pheromonal
cues
by
displacing
shortly
after
optogenetic
We
found
returned
location
predicted
memory-based
model.
Several
analyses
consistent
with
as
mechanism
conclude
although
often
important
fly
must
be
carefully
controlled
future
experiments,
may
performing
integration.
Language: Английский
Tracking Sugar-Elicited Local Searching Behavior in <em>Drosophila</em>
Journal of Visualized Experiments,
Journal Year:
2023,
Volume and Issue:
201
Published: Nov. 17, 2023
Foraging
behavior
is
essential
for
the
survival
of
organisms
as
it
enables
them
to
locate
and
acquire
food
resources.
In
Drosophila,
hunger
triggers
a
distinct
search
following
consumption
small
quantities
sugar
solution.
This
report
presents
simple
experimental
setup
study
sugar-elicited
with
aim
uncovering
underlying
mechanisms.
Minute
concentrated
solution
elicit
sustained
searching
in
flies.
The
involvement
path
integration
this
has
been
established,
flies
utilize
their
trajectory
return
location.
most
recent
findings
provide
evidence
temporal
modulation
initiation
intensity
after
intake.
We
have
also
used
artificial
activation
specific
taste-receptor
neurons
pharynx,
which
elicits
behavior.
Drosophila
neurogenetic
toolkit
offers
diverse
array
tools
techniques
that
can
be
combined
paradigm
neural
genetic
mechanisms
foraging.
Understanding
basis
hunger-driven
contributes
field
neurobiology
whole,
offering
insights
into
regulatory
govern
feeding
behaviors
not
only
other
but
humans.
Language: Английский
Exploration and exploitation are flexibly balanced during local search in flies
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 28, 2024
After
finding
food,
a
foraging
animal
must
decide
whether
to
continue
feeding,
or
explore
the
environment
for
potentially
better
options.
One
strategy
negotiate
this
tradeoff
is
perform
local
searches
around
food
but
repeatedly
return
feed.
We
studied
behavior
in
flies
and
used
genetic
tools
uncover
underlying
mechanisms.
Over
time,
gradually
expand
their
search,
shifting
from
primarily
exploiting
sources
exploring
environment,
change
that
likely
driven
by
increases
satiety.
found
flies’
search
patterns
preserve
these
dynamics
even
as
overall
scale
of
modulated
starvation-induced
changes
metabolic
state.
In
contrast,
induced
optogenetic
activation
sugar
sensing
neurons
does
not
show
dynamics.
asked
what
navigational
strategies
underlie
search.
Using
generative
model,
we
locomotor
pattern
after
consumption
could
account
repeated
returns
failed
capture
relatively
direct,
long
trajectories.
Alternative
strategies,
such
path
integration
sensory
taxis
allow
larger
distances.
tested
individually
silencing
fly’s
head
direction
system,
olfaction
hygrosensation,
only
substantial
effect
was
perturbing
which
reduced
number
exploratory
trips.
Our
study
illustrates
composed
multiple
behavioral
features
evolve
over
time
based
on
both
internal
external
factors,
providing
towards
uncovering
neural
Language: Английский