BMC Medicine, Journal Year: 2024, Volume and Issue: 22(1)
Published: Nov. 12, 2024
Intermittent fasting (IF) holds promise for enhancing metabolic health. However, the optimum IF forms and their superiority over continuous energy restriction (CER) remain unclear due to disconnected findings.
Language: Английский
Diabetes Research and Clinical Practice, Journal Year: 2022, Volume and Issue: 185, P. 109185 - 109185
Published: Jan. 8, 2022
Language: Английский
Citations
137
International Journal of Environmental Research and Public Health, Journal Year: 2020, Volume and Issue: 17(14), P. 5028 - 5028
Published: July 13, 2020
Menopause is an inevitable developmental event that women encounter at age of 42–54 years. The drop estrogen levels accompanies cessation menstruation associated with multiple vasomotor, physical, neuropsychological, and sexual symptoms, which may hamper quality life. This study aimed to examine the severity psychological symptoms their correlates among peri- postmenopausal Emirati (N = 60, mean 54.88 ± 6 years). Participants were interviewed using Menopause-Specific Quality Life (MENQOL) attitudes toward menopause scale (ATMS). In four path analysis models, vasomotor weight gain, fatigue had significant direct effects on anxiety, depression (only gain fatigue), distress. Fatigue significantly mediated symptoms), distress, memory problems. These models explained 47.6%, 44.5%, 56.6%, 29.1% variances in depression, problems, respectively. more severe menopausal expressed negative though regression revealed only could contribute ATMS scores. conclusion, distress widespread women, it fatigue, change body composition (obesity). Psychological along express a key link menopause. Therefore, interventional strategies target promote coping midlife transition improve mental health women.
Language: Английский
Citations
109
Diabetes Research and Clinical Practice, Journal Year: 2020, Volume and Issue: 165, P. 108226 - 108226
Published: May 21, 2020
Language: Английский
Citations
78
Nutrition Metabolism and Cardiovascular Diseases, Journal Year: 2021, Volume and Issue: 31(8), P. 2273 - 2301
Published: May 25, 2021
Language: Английский
Citations
71
Frontiers in Nutrition, Journal Year: 2022, Volume and Issue: 9
Published: July 26, 2022
Dietary regimens are crucial in the management of non-alcoholic fatty liver disease (NAFLD). The effects intermittent fasting (IF) have gained attention this regard, but further research is warranted. Thus, we aimed to ascertain overall 5:2 IF diet (5 days a week normal food intake and 2 consecutive days) patients with NAFLD compared control group (usual diet).A 12-week randomized controlled trial was performed evaluate on anthropometric indices, body composition, serum lipids, glucose metabolism, inflammatory markers NAFLD. (n = 21) decreased weight (86.65 ± 12.57-82.94 11.60 kg), mass index (30.42 2.27-29.13 1.95 kg/m2), waist circumference (103.52 6.42-100.52 5.64 cm), fat (26.64 5.43-23.85 5.85 fibrosis (6.97 1.94-5.58 1.07 kPa), steatosis scores/CAP (313.09 25.45-289.95 22.36 dB/m), alanine aminotransferase (41.42 20.98-28.38 15.21 U/L), aspartate (34.19 10.88-25.95 7.26 triglycerides (171.23 39.88-128.04 34.88 mg/dl), high-sensitivity C-reactive protein (2.95 0.62 -2.40 0.64 mg/L), cytokeratin-18 (1.32 0.06-1.19 0.05 ng/ml) values baseline end 23)-p ≤ were considered as significant. However, intervention did not change levels high-density lipoprotein cholesterol, total low-density blood sugar, insulin, HOMA-IR, antioxidant capacity.Adhering can reduce loss related parameters (fat indicators obesity), well hepatic steatosis, enzymes, triglycerides, biomarkers
Language: Английский
Citations
45
Medicina, Journal Year: 2024, Volume and Issue: 60(1), P. 191 - 191
Published: Jan. 22, 2024
Background: The potential positive interaction between intermittent fasting (IF) and brain-derived neurotrophic factor (BDNF) on cognitive function has been widely discussed. This systematic review tried to assess the efficacy of interventions with different IF regimens BDNF levels their association functions in humans. Interventions forms such as caloric restriction (CR), alternate-day (ADF), time-restricted eating (TRE), Ramadan model (RIF) were targeted. Methods: A was conducted for experimental observational studies healthy people patients diseases published EMBASE, Scopus, PubMed, Google Scholar databases from January 2000 December 2023. We followed Preferred Reporting Items Systematic Reviews Meta-Analysis statements (PRISMA) writing this review. Results: Sixteen research works metabolic disorders met inclusion criteria Five showed a significant increase after intervention, while five reported decrease levels, other six no changes due regimens. Moreover, examined RIF protocol, which, three reduction, two along an improvement RIF. Conclusions: current findings suggest that varying effects healthy, overweight/obese individuals conditions. However, few human have shown increases controversial results. In humans, yet be fully investigated terms its long-term effect functions. Large-scale, well-controlled high-quality data are warranted elucidate impact
Language: Английский
Citations
11
Nutrients, Journal Year: 2024, Volume and Issue: 16(3), P. 357 - 357
Published: Jan. 25, 2024
The efficacy of intermittent fasting (IF), as an emerging weight management strategy, in improving cardiometabolic health has been evaluated various populations, but that among Chinese individuals not systematically studied. A comprehensive search on multiple databases was performed to identify eligible randomized controlled trials (RCTs) up October 2022. primary outcome post-intervention loss, and secondary outcomes included changes indicators. Effect estimates were meta-analyzed using a random-effects model. In total, nine RCTs with 899 participants included. Time-restricted eating the most adopted IF protocol this study (six out nine), followed by alternate-day fasting. intervention significantly reduced body weight, mass index, fat mass, homeostatic model assessment insulin resistance, low-density lipoprotein cholesterol, triglycerides when compared control groups. However, no statistically significant reductions waist circumference, total high-density glucose, systolic blood pressure, diastolic pressure found. To sum up, can be strategy may improve adults, more long-term different strategies are required generate robust evidence its efficacy.
Language: Английский
Citations
10
Nutrients, Journal Year: 2020, Volume and Issue: 12(8), P. 2478 - 2478
Published: Aug. 17, 2020
Ramadan fasting is a form of time-restricted feeding which combines fast and feast period daily for duration one month every year. During Ramadan, Muslims abstain from food drink consumption dawn till sunset this change in the meal schedule frequency results significant changes to composition diet, such as energy nutrient intake. These dietary habits their corresponding effects on cardiometabolic disease risk are compiled review. shows limited benefits body via reductions mass both healthy obese individuals, although often found be transient heterogeneous. There is, however, more consistent improvement blood lipid profile during fasting, lasts beyond period. The glucose homeostasis, contrary, conflicting inconclusive. heterogeneity findings various studies can generally attributed cultural variations habits, differences due seasonal/climatic at geographical locations, age, gender socioeconomic status, well other health lifestyle factors study populations.
Language: Английский
Citations
61
Frontiers in Endocrinology, Journal Year: 2021, Volume and Issue: 12
Published: March 8, 2021
Ramadan is the 9th month of lunar calendar during which Muslims abstain from food and drink between dawn sunset for 30 consecutive days. fasting observed by all healthy Muslim adults, as well many with type 2 diabetes (T2DM). Hypoglycemic events (HE) are a serious complication associated management increased cardiovascular disease risk. Conflicting results have been reported concerning incidence HE among people T2DM observing fasting. This review summarizes available scientific evidence on occurrence effects different moderators patients Ramadan. We conducted systematic observational studies randomized controlled trials (RCTs) who fasted Ramadan, primary outcome. Ten databases were searched relevant inception until October 31, 2020. In total, 68 (35 RCTs 33 studies) met inclusion criteria. Non-sulfonylureas hypoglycemic medications showed superior in lowering over sulfonylureas medications. Variable experiencing both RCTs, including sex, geographical location, body anthropometric indicators, season, dietary behaviors, duration, time since diagnosis, pre-fasting education. comprehensive covered largest number clinical investigating impact T2DM. The study highlights significance that influence effect HE, country, education, age, diagnosis. also highlighted noted superiority non-sulfonylureas risk hypoglycemia
Language: Английский
Citations
55
Diabetes Research and Clinical Practice, Journal Year: 2021, Volume and Issue: 178, P. 108951 - 108951
Published: July 14, 2021
Language: Английский
Citations
54