Semen in the time of COVID-19: a narrative review of current evidence and implications for fertility and reproductive health DOI Creative Commons
Bonaventure Michael Ukoaka, Olalekan John Okesanya,

Monica Anurika Gbuchie

et al.

Middle East Fertility Society Journal, Journal Year: 2024, Volume and Issue: 29(1)

Published: Aug. 20, 2024

Abstract Background Historically, viruses have impaired the functionality of human systems. The discovery novel and resurgence established strains heighten concerns about their implications for reproduction. In aftermath COVID-19, research efforts intensified to broaden understanding severe acute respiratory syndrome coronavirus-2’s (SARS-CoV-2) effect on male reproduction across diverse populations. Various findings been reported, with more studies highlighting adverse impact SARS-CoV-2 semen parameters and, consequently, fertility. This review aims comprehensively assess consolidate existing evidence quality It highlights potential mechanism action further underscores assisted reproductive technology. Methodology A thorough literature search was conducted various electronic databases, including PubMed, Scopus, Google Scholar, Embase, Web Science. Studies published between January 2020 May 2024 were included if they explored quality. Results Twenty-nine (29) in review. These varied but delineated a pattern trend. While most noted decline sperm parameters—motility, count, concentration—altered morphology, hormonal imbalances, increased DNA fragmentation COVID-19 patients, others reported normal 3 6 months post-recovery. Few no change parameters, especially mild disease. Potential mechanisms underscoring these effects include presence fever consequent release pro-inflammatory cytokines—interleukin 1β, tumor necrosis factor (TNF), interferon-gamma (IFNγ). addition, activities angiotensin-converting enzyme 2 (ACE2) transmembrane serine protease (TMPRSS2) receptors implicated as gateway viral entry. long-term consequences comparisons other infections highlight complexity drawing definite conclusions. different changes family planning. Research suggests negative gonadal function, emphasizing need follow-up understand persistent fertility biomarkers. Conclusion multidisciplinary approach is essential optimizing health during after infection. includes incorporating assessments into vaccine safety address concerns.

Language: Английский

SARS-CoV-2 infection, vaccination and in vitro fertilization treatment: A prospective cohort study DOI
Xudong Zhang, Xinyao Li,

Wanmeng Chen

et al.

International Immunopharmacology, Journal Year: 2024, Volume and Issue: 135, P. 112291 - 112291

Published: May 20, 2024

Language: Английский

Citations

4
The Effect of COVID-19 and COVID-19 Vaccination on Assisted Human Reproduction Outcomes: A Systematic Review and Meta-Analysis DOI Creative Commons
Andrea Milostić-Srb, Nika Srb, Jasminka Talapko

et al.

Diseases, Journal Year: 2024, Volume and Issue: 12(9), P. 201 - 201

Published: Sept. 3, 2024

The most discussed infectious disease is coronavirus 2019 (COVID-19), caused by the severe acute respiratory syndrome 2 (SARS-CoV-2) virus. Many research endeavors have focused on effects of virus reproductive organs, as these also been shown to carry receptors which attaches. results assisted technology (ART) significantly affected pandemic, with some in vitro fertilization (IVF) centers being closed due risk further spread disease. According World Health Organization statistics, 17.5% adults worldwide suffered from fertility problems 2023; other words, one six people world health problems. As infertility a growing problem modern and new developments reproduction are always topic profound interest, it important understand impact SARS-CoV-2 health. This systematic review aimed examine studies describing patients undergoing ART procedures COVID-19-positive history shed light recent evidence safety COVID-19 vaccination context. A meta-analysis was conducted confirm review. showed significant difference clinical pregnancy rates between vaccinated unvaccinated groups an increased miscarriage rate those history. However, no birth found participants previous infection. show that needed, even though decreased. Evidence-based information for individuals couples treatment vital enable informed decision-making.

Language: Английский

Citations

2
Semen in the time of COVID-19: a narrative review of current evidence and implications for fertility and reproductive health DOI Creative Commons
Bonaventure Michael Ukoaka, Olalekan John Okesanya,

Monica Anurika Gbuchie

et al.

Middle East Fertility Society Journal, Journal Year: 2024, Volume and Issue: 29(1)

Published: Aug. 20, 2024

Abstract Background Historically, viruses have impaired the functionality of human systems. The discovery novel and resurgence established strains heighten concerns about their implications for reproduction. In aftermath COVID-19, research efforts intensified to broaden understanding severe acute respiratory syndrome coronavirus-2’s (SARS-CoV-2) effect on male reproduction across diverse populations. Various findings been reported, with more studies highlighting adverse impact SARS-CoV-2 semen parameters and, consequently, fertility. This review aims comprehensively assess consolidate existing evidence quality It highlights potential mechanism action further underscores assisted reproductive technology. Methodology A thorough literature search was conducted various electronic databases, including PubMed, Scopus, Google Scholar, Embase, Web Science. Studies published between January 2020 May 2024 were included if they explored quality. Results Twenty-nine (29) in review. These varied but delineated a pattern trend. While most noted decline sperm parameters—motility, count, concentration—altered morphology, hormonal imbalances, increased DNA fragmentation COVID-19 patients, others reported normal 3 6 months post-recovery. Few no change parameters, especially mild disease. Potential mechanisms underscoring these effects include presence fever consequent release pro-inflammatory cytokines—interleukin 1β, tumor necrosis factor (TNF), interferon-gamma (IFNγ). addition, activities angiotensin-converting enzyme 2 (ACE2) transmembrane serine protease (TMPRSS2) receptors implicated as gateway viral entry. long-term consequences comparisons other infections highlight complexity drawing definite conclusions. different changes family planning. Research suggests negative gonadal function, emphasizing need follow-up understand persistent fertility biomarkers. Conclusion multidisciplinary approach is essential optimizing health during after infection. includes incorporating assessments into vaccine safety address concerns.

Language: Английский

Citations

0