medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Oct. 23, 2023
Abstract
Background
Limited
data
about
chronic
post-COVID
neuropsychiatric
complaints
exist
in
the
literature.
Aim
Our
study
aims
to
delineate
phenotypes
of
symptoms
among
adult
subjects
recovering
from
their
first
COVID
that
occurred
more
than
one
year
ago.
We
also
aim
explore
clinical
and
socioeconomic
risk
factors
having
a
high
loading
symptoms.
Methods
recruited
group
who
suffered
pre-Omicron
ago,
control
had
never
COVID.
The
completed
app-based
questionnaires
on
demographic,
health
status,
checklist,
mental
sleep
measures,
neurocognitive
tests.
Results
has
statistically
significantly
higher
level
fatigue
compared
(p<0.001).
Among
group,
lack
any
vaccination
before
material
deprivation
pandemic
predicts
load
Partial
correlation
network
analysis
suggests
can
be
clustered
into
two
major
(cognitive
-fatigue
anxiety-depression)
minor
(headache-dizziness)
cluster.
A
number
both
clusters,
but
only
cognitive
complaints-fatigue
Conclusions
result
heterogeneity
symptoms,
which
are
associated
with
complex
interplay
biological
factors.
Translational Psychiatry,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: June 19, 2024
Abstract
Our
study
aims
to
delineate
the
phenotypes
of
chronic
neuropsychiatric
symptoms
among
adult
subjects
recovering
from
their
first
COVID
that
occurred
more
than
one
year
ago.
We
also
aim
explore
clinical
and
socioeconomic
risk
factors
having
a
high
loading
symptoms.
recruited
post-COVID
group
who
suffered
pre-Omicron
ago,
control
had
never
COVID.
The
completed
app-based
questionnaires
on
demographic,
health
status,
checklist,
mental
sleep
measures,
neurocognitive
tests.
has
statistically
significantly
higher
level
fatigue
compared
(
p
<
0.001).
Among
group,
lack
any
vaccination
before
material
deprivation
pandemic
predicts
load
Partial
correlation
network
analysis
suggests
can
be
clustered
into
two
major
(cognitive
complaints
-fatigue
anxiety-depression)
minor
(headache-dizziness)
cluster.
A
number
in
both
clusters,
but
only
cognitive
complaints-fatigue
result
heterogeneity
symptoms,
which
are
associated
with
complex
interplay
biological
factors.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 4, 2024
Abstract
Importance
Existing
systematic
literature
reviews
(SLRs)
on
COVID-19
vaccine
effectiveness
(VE)
against
post-COVID-19
conditions
(PCC)
document
high
heterogeneity
across
studies,
but
have
not
compared
VE
design
features
known
to
impact
PCC
burden
or
other
endpoints.
Objective
This
SLR
summarizes
the
evidence
studies
among
predominately
adults
that
report
an
adjusted
measure
of
association
for
relationship
between
vaccination
and
PCC,
by
timing
relative
infection
PCC-onset
different
study
characteristics.
Evidence
review
A
comprehensive
search
strategy
was
developed
within
OVID
platform
EMBASE,
MEDLINE®
Evidence-Based
Medicine
reviews,
supplemented
with
WHO
COVID
library
Google
Scholar®
searches,
collate
published
posted
as
pre-prints
January
1
st
,
2020
July
18
th
2023.
JBI
Critical
Appraisal
Checklists
were
used
assess
each
study’s
risk
bias.
Findings
included
97
synthesized
results
from
56
low
bias
reported
measures
PCC.
Overall,
77%
pre-infection
(aVE)
estimates
(vs.
unvaccinated)
statistically
significant
(range:
7%–95%),
80%
reflecting
a
mix
those
vaccinated
before
after
62%–73%),
one
five
onset
(aVE=41%),
43%
post-infection
(two
protective
[range:
28%–40%]
[aVE=-47%]),
46%
specifying
(23
29%–75%]
[aVE=-132%]).
Statistically
aVE
slightly
higher
mRNA
14%–84%)
than
non-mRNA
vaccines
16%–38%)
ranges
during
(4
studies;
range:
10%–70%)
Omicron
predominance
(10
7%–50%)
overlapped.
Pre-infection
regardless
type,
number
doses
received,
definition,
predominant
variant,
severity
acute
infections
included.
Conclusions
Relevance
Collectively
our
findings
suggest
received
prior
SARS-CoV-2
reduces
subsequent
developing
variant
circulating.
Key
points
Question
Do
vary
onset,
type
disease
severity?
appeared
reduce
unvaccinated).
Compared
types,
seemed
offer
greater
protection,
dose
response
observed
vaccines.
Meaning
Despite
reduced
≥1
proportion
sample
hospitalized,
definition.
Frontiers in Public Health,
Journal Year:
2024,
Volume and Issue:
12
Published: Nov. 26, 2024
The
COVID-19
pandemic,
which
began
worldwide
around
March
2020,
has
had
an
impact
on
hearing
health,
specifically
tinnitus
and
loss.
Physiologically,
infection,
or
medication
used
to
treat
the
been
reported
be
a
potential
risk
factor
for
onset.
In
addition,
was
long
COVID
symptom
occur
after
vaccination
in
some
cases.
With
most
reports
focused
clinical
population,
this
study
aimed
investigate
how
onset
of
is
associated
with
COVID,
general
population
based
self-report,
while
accounting
otologic
psychological
symptoms.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Oct. 23, 2023
Abstract
Background
Limited
data
about
chronic
post-COVID
neuropsychiatric
complaints
exist
in
the
literature.
Aim
Our
study
aims
to
delineate
phenotypes
of
symptoms
among
adult
subjects
recovering
from
their
first
COVID
that
occurred
more
than
one
year
ago.
We
also
aim
explore
clinical
and
socioeconomic
risk
factors
having
a
high
loading
symptoms.
Methods
recruited
group
who
suffered
pre-Omicron
ago,
control
had
never
COVID.
The
completed
app-based
questionnaires
on
demographic,
health
status,
checklist,
mental
sleep
measures,
neurocognitive
tests.
Results
has
statistically
significantly
higher
level
fatigue
compared
(p<0.001).
Among
group,
lack
any
vaccination
before
material
deprivation
pandemic
predicts
load
Partial
correlation
network
analysis
suggests
can
be
clustered
into
two
major
(cognitive
-fatigue
anxiety-depression)
minor
(headache-dizziness)
cluster.
A
number
both
clusters,
but
only
cognitive
complaints-fatigue
Conclusions
result
heterogeneity
symptoms,
which
are
associated
with
complex
interplay
biological
factors.
