MRI-Negative Temporal Lobe Epilepsy: A Study of Brain Structure in Adults Using Surface-Based Morphological Features DOI Creative Commons
Yuting He, Ying Huang, Zhe Guo

et al.

Journal of Integrative Neuroscience, Journal Year: 2024, Volume and Issue: 23(11)

Published: Nov. 20, 2024

Background: This research aimed to delve into the cortical morphological transformations in patients with magnetic resonance imaging (MRI)-negative temporal lobe epilepsy (TLE-N), seeking uncover neuroimaging mechanisms behind these changes. Methods: A total of 29 individuals diagnosed TLE-N and 30 healthy control participants matched by age sex were selected for study. Using surface-based morphometry (SBM) technique, study analyzed three-dimensional-T1-weighted MRI scans participants' brains. Various structure characteristics, such as thickness, surface area, volume, curvature, sulcal depth, among other parameters, measured. Results: When compared group, exhibited increased insular cortex thickness both brain hemispheres. Additionally, there was a notable reduction curvature piriform (PC) granular complex within right hemisphere. In left hemisphere, volume secondary sensory (OP1/SII) third visual area significantly reduced group. However, no significant differences found between groups regarding depth (p < 0.025 all, corrected threshold-free cluster enhancement). Conclusions: The study's initial findings suggest subtle changes cerebral patients. SBM technique proved effective identifying regions impacted epileptic activity. Understanding microstructural morphology offers insights pathophysiological underlying TLE.

Language: Английский

Effects of rhythmic-cued gait training on gait-like task related brain activation in people with multiple sclerosis DOI Creative Commons
Birgit Helmlinger, Barbara Seebacher, Stefan Ropele

et al.

Journal of the Neurological Sciences, Journal Year: 2025, Volume and Issue: 471, P. 123426 - 123426

Published: Feb. 13, 2025

Language: Английский

Citations

0
Effectiveness of robotic rehabilitation for gait and balance in people with multiple sclerosis: a systematic review DOI
Salvatore Facciorusso, Calogero Malfitano,

Martino Giordano

et al.

Journal of Neurology, Journal Year: 2024, Volume and Issue: 271(11), P. 7141 - 7155

Published: Oct. 10, 2024

Language: Английский

Citations

1
MRI-Negative Temporal Lobe Epilepsy: A Study of Brain Structure in Adults Using Surface-Based Morphological Features DOI Creative Commons
Yuting He, Ying Huang, Zhe Guo

et al.

Journal of Integrative Neuroscience, Journal Year: 2024, Volume and Issue: 23(11)

Published: Nov. 20, 2024

Background: This research aimed to delve into the cortical morphological transformations in patients with magnetic resonance imaging (MRI)-negative temporal lobe epilepsy (TLE-N), seeking uncover neuroimaging mechanisms behind these changes. Methods: A total of 29 individuals diagnosed TLE-N and 30 healthy control participants matched by age sex were selected for study. Using surface-based morphometry (SBM) technique, study analyzed three-dimensional-T1-weighted MRI scans participants' brains. Various structure characteristics, such as thickness, surface area, volume, curvature, sulcal depth, among other parameters, measured. Results: When compared group, exhibited increased insular cortex thickness both brain hemispheres. Additionally, there was a notable reduction curvature piriform (PC) granular complex within right hemisphere. In left hemisphere, volume secondary sensory (OP1/SII) third visual area significantly reduced group. However, no significant differences found between groups regarding depth (p < 0.025 all, corrected threshold-free cluster enhancement). Conclusions: The study's initial findings suggest subtle changes cerebral patients. SBM technique proved effective identifying regions impacted epileptic activity. Understanding microstructural morphology offers insights pathophysiological underlying TLE.

Language: Английский

Citations

0