Acta Physica Sinica, Journal Year: 2024, Volume and Issue: 73(18), P. 180502 - 180502
Published: Jan. 1, 2024
The pre-Bötzinger complex is a crucial region for generating respiratory rhythms in mammals. Peripheral chemoreceptors have significant influence on rhythm by monitoring changes blood oxygen concentration and carbon dioxide concentration. This study introduces closed-loop control model, which driven electromagnetic induction based the activation of neurons. model incorporates various factors including motor pool, lung volume, oxygen, chemoreceptors. response system subjected to same hypoxic perturbation under different studied, effect magnetic flux feedback coefficient recovery mixed investigated. Using bifurcation analysis numerical simulations, it found that has ability recover rhythm. dynamic mechanism responses systems are revealed. Dynamic indicates certain induction, bursting can autoresuscitate if structure before after applying hypoxia completely identical. However, when different, cannot autoresuscitate. In addition, cases where automatic not achieved mild increasing appropriately lead autoresuscitate, closely related Hopf fold limit cycle. contributes understanding interaction between central peripheral chemoreceptive rhythm, as well external response.
Language: Английский