Tumor location is associated with mood dysfunction in patients with diffuse glioma
Nature Mental Health,
Journal Year:
2024,
Volume and Issue:
2(7), P. 853 - 864
Published: July 11, 2024
Abstract
Gliomas
are
primary
brain
tumors
that
can
cause
neuropsychiatric
symptoms,
including
severe
depressive
symptoms
(SDS;
in
14%)
and
an
absence
of
(ADS;
29%),
determined
by
Center
for
Epidemiologic
Studies
Depression
(CES-D)
scores.
We
examined
the
association
between
both
SDS
ADS
tumor
location
201
patients
with
diffuse
glioma
before
surgery.
Tumors
white
matter
disconnectomes
did
not
relate
to
CES-D
using
sparse
canonical
correlation
analysis.
were
associated
right
corticospinal
tract,
fornix,
inferior
fronto-occipital
fasciculus
left
uncinate
fasciculus,
whereas
was
first
segment
superior
longitudinal
temporal
cingulum
thalamus
Bayesian
regression
analyses.
occurs
even
more
frequently
than
does
SDS,
which
is
explained
partly
location.
This
research
aids
understanding
gliomas
mood
dysfunction
general.
Language: Английский
Post-stroke changes in brain structure and function can both influence acute upper limb function and subsequent recovery
NeuroImage Clinical,
Journal Year:
2025,
Volume and Issue:
45, P. 103754 - 103754
Published: Jan. 1, 2025
Improving
outcomes
after
stroke
depends
on
understanding
both
the
causes
of
initial
function/impairment
and
mechanisms
recovery.
Recovery
in
patients
with
initially
low
function/high
impairment
is
variable,
suggesting
factors
relating
to
are
different
important
for
subsequent
Here
we
aimed
determine
contribution
altered
brain
structure
function
severity
recovery
upper
limb
post-stroke.
The
Nine-Hole
Peg
Test
was
recorded
week
1
one-month
post-stroke
used
divide
36
(18
females,
age:
M
=
66.56
years)
into
those
high/low
We
determined
differences
(Magnetic
Resonance
Imaging)
(Magnetoencephalography,
tactile
stimulation)
between
Lastly,
examined
relative
changes
levels
function.
Low
related
lower
sensorimotor
β
power
greater
lesion-induced
disconnection
contralateral
[ipsilesional]
white-matter
motor
projection
connections.
Moreover,
intra-hemispheric
connectivity
(structural
functional)
unique
function,
while
inter-hemispheric
Function-related
recovery-related
related,
yet
not
identical.
Separating
out
that
contribute
each
process
key
identifying
potential
therapeutic
targets
improving
outcomes.
Language: Английский
Imaging Biomarkers of VCI: A Focused Update
Stroke,
Journal Year:
2024,
Volume and Issue:
55(4), P. 791 - 800
Published: March 6, 2024
Vascular
cognitive
impairment
is
common
after
stroke,
in
memory
clinics,
medicine
for
the
elderly
services,
and
undiagnosed
community.
disease
said
to
be
second
most
cause
of
dementia
Alzheimer
disease,
yet
vascular
dysfunction
now
known
predate
decline
dementias
at
older
ages
are
mixed.
Neuroimaging
has
a
major
role
identifying
proportion
versus
other
likely
pathologies
patients
with
impairment.
Here,
we
aim
provide
pragmatic
but
evidence-based
summary
current
state
potential
imaging
biomarkers,
focusing
on
magnetic
resonance
computed
tomography,
which
relevant
diagnosing,
estimating
prognosis,
monitoring
impairment,
incorporating
our
own
experiences.
We
focus
markers
that
well-established,
profile
association
measures,
also
consider
more
recently
described,
including
quantitative
tissue
injury.
highlight
gaps
accessibility
translation
routine
clinical
practice.
Language: Английский
Symptomatology after damage to the angular gyrus through the lenses of modern lesion-symptom mapping
Cortex,
Journal Year:
2024,
Volume and Issue:
179, P. 77 - 90
Published: Aug. 3, 2024
Language: Английский
Post-stroke changes in brain structure and function can both influence acute upper limb function and subsequent recovery
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 4, 2024
Abstract
Improving
outcomes
after
stroke
depends
on
understanding
both
the
causes
of
initial
function/impairment
and
mechanisms
recovery.
Recovery
in
patients
with
initially
low
function/high
impairment
is
variable,
suggesting
factors
relating
to
are
different
important
for
subsequent
Here
we
aimed
determine
contribution
altered
brain
structure
function
severity
recovery
upper
limb
post-stroke.
The
Nine-Hole
Peg
Test
was
recorded
week
1
one-month
post-stroke
used
divide
36
(18
females,
age:
M
=
66.56
years)
into
those
high/low
We
determined
differences
(Magnetic
Resonance
Imaging)
(Magnetoencephalography,
tactile
stimulation)
between
Lastly,
examined
relative
changes
levels
function.
Low
related
lower
sensorimotor
β
power
greater
lesion-induced
disconnection
contralateral
[ipsilesional]
white-matter
motor
projection
connections.
Moreover,
intra-hemispheric
connectivity
(structural
functional)
unique
function,
while
inter-hemispheric
Function-related
recovery-related
related,
yet
not
identical.
Separating
out
that
contribute
each
process
key
identifying
potential
therapeutic
targets
improving
outcomes.
Language: Английский