The Journal of Infectious Diseases,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 20, 2024
Developing
effective
vaccines
is
necessary
in
combating
new
virus
pandemics.
For
HIV
and
SARS-CoV-2,
the
induction
of
neutralizing
antibodies
(NAb)
important
for
vaccine
protection;
however,
exact
mechanisms
underlying
protection
require
further
study.
Recent
data
emphasize
that
even
Abs
do
not
exhibit
activity
may
contribute
to
immune
defense.
exhibiting
this
function
counter
mutations,
which
are
acquired
escape
from
NAbs,
therefore,
broaden
protective
Ab
response
induced
by
vaccination.
However,
steps
leading
Fc-mediated
inhibition
complex.
How
can
these
functions
be
measured
vitro?
What
inhibitory
assay
most
physiologically
relevant
at
mimicking
vivo
protection?
This
review
provides
a
comprehensive
update
on
current
knowledge
gaps
involved
SARS-CoV-2
protection.
Understanding
effects
vital
designing
next
generation
vaccines.
Frontiers in Immunology,
Journal Year:
2024,
Volume and Issue:
15
Published: July 19, 2024
Enhancing
livestock
biosecurity
is
critical
to
safeguard
the
livelihoods
of
farmers,
global
and
local
economies,
food
security.
Vaccination
fundamental
control
prevention
exotic
endemic
high-priority
infectious
diseases.
Successful
implementation
vaccination
in
a
plan
underpinned
by
strong
understanding
correlates
protection—those
elements
immune
response
that
can
reliably
predict
level
protection
from
viral
challenge.
While
have
been
successfully
characterized
for
many
human
vaccines,
diseases,
including
African
swine
fever
foot
mouth
disease,
they
remain
largely
uncharacterized.
Current
literature
provides
insights
into
potential
should
be
assessed
during
vaccine
development
these
mammalian
Establishment
purposes
enables
surveillance,
rationale
development,
successful
vaccines
as
part
strategy.
The Journal of Infectious Diseases,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 20, 2024
Developing
effective
vaccines
is
necessary
in
combating
new
virus
pandemics.
For
HIV
and
SARS-CoV-2,
the
induction
of
neutralizing
antibodies
(NAb)
important
for
vaccine
protection;
however,
exact
mechanisms
underlying
protection
require
further
study.
Recent
data
emphasize
that
even
Abs
do
not
exhibit
activity
may
contribute
to
immune
defense.
exhibiting
this
function
counter
mutations,
which
are
acquired
escape
from
NAbs,
therefore,
broaden
protective
Ab
response
induced
by
vaccination.
However,
steps
leading
Fc-mediated
inhibition
complex.
How
can
these
functions
be
measured
vitro?
What
inhibitory
assay
most
physiologically
relevant
at
mimicking
vivo
protection?
This
review
provides
a
comprehensive
update
on
current
knowledge
gaps
involved
SARS-CoV-2
protection.
Understanding
effects
vital
designing
next
generation
vaccines.
