The microbiota: a key regulator of health, productivity, and reproductive success in mammals

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 5, 2024

The microbiota, intensely intertwined with mammalian physiology, significantly impacts health, productivity, and reproductive functions. normal microbiota interacts the host through following key mechanisms: acting as a protective barrier against pathogens, maintain mucosal integrity, assisting in nutrient metabolism, modulating of immune response. Therefore, supporting growth development host, providing protection pathogens toxic substances. influences brain behavior, demonstrated by comprehensive findings from controlled laboratory experiments human clinical studies. prospects suggested that gut microbiome influence neurodevelopmental processes, modulate stress responses, affect cognitive function gut-brain axis. Microbiota gastrointestinal tract farm animals break down ferment ingested feed into nutrients, utilize to produce meat milk. Among beneficial by-products short-chain fatty acids (SCFAs) are particularly noteworthy for their substantial role disease prevention promotion various productive aspects mammals. plays pivotal hormonal systems mammals, boosting performance both sexes fostering maternal-infant connection, thereby becoming crucial factor sustaining existence. is critical influencing success production traits A well-balanced improves absorption metabolic efficiency, leading better rates, increased milk production, enhanced overall health. Additionally, it regulates hormones like estrogen progesterone, which essential successful conception pregnancy. Understanding offers valuable insights optimizing breeding improving outcomes, contributing advancements agriculture veterinary medicine. This study emphasizes ecological roles highlighting contributions success. By integrating perspectives, demonstrates how microbial communities enhance function, regulation across species, offering benefit agricultural advancements.

Language: Английский

Compendium of lactopontin: Molecular Structure, Manufacturing Process and Biological Functions

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106155 - 106155

Published: Feb. 1, 2025

Language: Английский

Gut Microbiota-Derived Metabolites and Their Role in the Pathogenesis of Necrotizing Enterocolitis in Preterm Infants: A Narrative Review

Metabolites, Journal Year: 2024, Volume and Issue: 14(11), P. 570 - 570

Published: Oct. 23, 2024

: Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease that occurs predominantly in premature infants and characterized by the inflammation necrosis of intestine, showing high morbidity mortality rates. Despite decades research efforts, specific treatment currently lacking, preventive strategies are mainstays care. This review aims to help understand complex interplay between gut microbiota their metabolites NEC pathogenesis. In particular, we focused on how these factors can influence health, immune responses, intestinal barrier integrity.

Language: Английский