Global, Regional, and National Burdens of Hepatitis E From 1990 to 2021 and Predicted 2030 Incidence: Results From the Global Burden of Disease Study 2021 DOI Open Access

Boyi Wu,

Yu‐Xin Tian, Jing Zuo

et al.

Journal of Medical Virology, Journal Year: 2025, Volume and Issue: 97(3)

Published: Feb. 28, 2025

ABSTRACT Our objective was to evaluate the shifting burden of hepatitis E virus (HEV) across age groups and geographical scopes from 1990 2021 predict incidence rates for 2030. Leveraging data Global Burden Diseases 2021, we examined HEV disability‐adjusted life years, calculated average annual percentage changes (AAPCs) identified pivotal years trends. We stratified our analysis by age, sex, sociodemographic index employed Bayesian age‐period‐cohort model future incidence. decreased 269.68 per 100,000 in 260.41 with an AAPC −0.1. Notably, significantly 1995, 2006, 2009, 2014. Southern sub‐Saharan Africa presented most notable increase infection incidence, increasing 218.59 individuals (95% [UI] 181.36 262.28) 232.25 (191.9 279.82), 0.2 [CI] 0.2). The 2030 is projected be 267.44 UI, 235.27 299.6). Despite a general decline associated health interventions, some regions still report increases, underscoring need intensified disease management meet goals.

Language: Английский

Global, Regional, and National Burdens of Hepatitis E From 1990 to 2021 and Predicted 2030 Incidence: Results From the Global Burden of Disease Study 2021 DOI Open Access

Boyi Wu,

Yu‐Xin Tian, Jing Zuo

et al.

Journal of Medical Virology, Journal Year: 2025, Volume and Issue: 97(3)

Published: Feb. 28, 2025

ABSTRACT Our objective was to evaluate the shifting burden of hepatitis E virus (HEV) across age groups and geographical scopes from 1990 2021 predict incidence rates for 2030. Leveraging data Global Burden Diseases 2021, we examined HEV disability‐adjusted life years, calculated average annual percentage changes (AAPCs) identified pivotal years trends. We stratified our analysis by age, sex, sociodemographic index employed Bayesian age‐period‐cohort model future incidence. decreased 269.68 per 100,000 in 260.41 with an AAPC −0.1. Notably, significantly 1995, 2006, 2009, 2014. Southern sub‐Saharan Africa presented most notable increase infection incidence, increasing 218.59 individuals (95% [UI] 181.36 262.28) 232.25 (191.9 279.82), 0.2 [CI] 0.2). The 2030 is projected be 267.44 UI, 235.27 299.6). Despite a general decline associated health interventions, some regions still report increases, underscoring need intensified disease management meet goals.

Language: Английский

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