Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Oct. 12, 2023
Abstract
There
has
been
a
scarcity
of
comprehensive
studies
that
aim
to
predict
both
the
levels
PM
2.5
particles
and
their
corresponding
impacts
on
human
health.
To
fill
this
gap,
we
developed
an
artificial
neural
network
model
AirQ+
software
concentrations
assess
associated
health
effects.
The
ANN
utilized
five
distinct
input
parameters,
specifically
wind
velocity,
orientation,
atmospheric
temperature,
relative
moisture
content,
levels,
observed
within
time
frame
2018
2019.
concealed
stratum
comprised
total
ten
neurons,
in
addition
presence
output
layer.
MLP
demonstrated
strong
correlations
at
each
stage:
0.908
(training),
0.910
(validation),
0.914
(testing),
0.907
overall.
RMSE
was
determined
as
6.52
µg/m
3
when
evaluating
network,
thus
indicating
notable
predictive
precision
exhibited
by
multilayer
perceptron
(MLP)
forecasting
concentration
particles.
software,
created
World
Health
Organization
(WHO),
employed
magnitude
consequences
concentrations.
average
throughout
duration
study
recorded
26.5
μg/m
,
which
exceeds
recommended
limit
provided
WHO
factor
5.3.
estimated
proportions
numbers
deaths
attributed
various
conditions.
Specifically,
chronic
obstructive
pulmonary
disease
(COPD),
ischemic
heart
(IHD),
lung
cancer
(LC),
stroke,
all-cause
mortality
accounted
for
approximately
11.67%,
15.02%,
13.25%,
15.225%,
9.45%
respectively.
number
were
19,195
all
causes,
10,063
COPD,
564
IHD,
1,063
cancer.
findings
investigation
demonstrate
high
degree
reliability
methodologies
utilized.
Through
utilization
these
approaches,
individuals
positions
authority
responsibility
can
aptly
evaluate
cost-benefit
analysis,
leading
reduction
casualties
mitigating
economic
burdens
society.
International Journal of Environmental Health Research,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 13
Published: Jan. 9, 2025
The
objective
of
this
study
was
to
estimate
the
health
effects
attributed
PM2.5
exposure
in
southwest
Iran.
In
order
HA-CVD,
HA-RD,
LC-M,
I-As
children,
RAD,
and
WDL,
exposure-response
function
method
used.
annual
mean
regularly
exceeded
5.26-8.5
times
from
2021
limit
value
established
by
WHO.
dominance
PM2.5/PM10
ratio
decreased
-34.6%
2015
2020.
results
showed
that
risks
HA-CVD
(-
51.
9),
HA-RD
68.7%),
LC-M
43.6%),
52.1%),
RAD
56.8%),
WDL
58.7%)
declined
per
105
inhabitants
between
2018
2020
.
Reducing
particulate
emissions
industries
road
traffic
led
lower
PM2.5,
which
will
be
effective
decrease
mortality
rate.
Ecotoxicology and Environmental Safety,
Journal Year:
2025,
Volume and Issue:
291, P. 117846 - 117846
Published: Feb. 1, 2025
This
study
investigates
the
association
between
fine
particulate
matter
(PM2.5)
exposure
and
acute
exacerbations
of
chronic
obstructive
pulmonary
disease
(AECOPD).
A
retrospective
analysis
was
conducted
on
1284
AECOPD
hospitalizations
at
Shanxi
Medical
University's
Second
Hospital
from
2018
to
2022.
data
paired
with
Shanxi's
average
monthly
PM2.5
Tracking
Air
Pollution
in
China
(TAP)
dataset.
Correlations
levels
clinicopathological
features
were
assessed
using
ANOVA
Spearman's
correlation.
Higher
concentrations
observed
during
February-April
November-January,
correlating
increased
admissions
(r
=
0.754),
outpatient
visits
0.799),
emergency
0.447),
ICU
transfers
0.860).
Among
patients,
76.5
%
smokers
68.4
over
60
years
old.
Inflammatory
markers
(leukocyte
neutrophil
counts,
eosinophil
percentages,
C-reactive
protein),
D-dimer
levels,
PaCO2,
fibrosis
indicators
showed
positive
correlations
whereas
Pulmonary
Function
measures
(FEV1/
FVC,
FEV1
%)
PaO2
inverse
correlations.
Elevated
significantly
increases
risk
AECOPD,
linked
heightened
inflammation,
fibrosis,
diminished
function,
majority
these
patients
are
old
or
smokers.
provides
valuable
theoretical
practical
insights
for
proactive
prevention
management
clinical
settings.
Atmospheric Environment X,
Journal Year:
2024,
Volume and Issue:
21, P. 100246 - 100246
Published: Jan. 1, 2024
This
paper
discusses
the
impact
of
rapid
economic
development
on
air
quality
in
Emirate
Dubai,
United
Arab
Emirates
(UAE).
Dubai
is
one
fastest-growing
cities
world,
with
a
population
increase
approximately
80
×
over
last
60
years.
The
concentrations
five
criteria
pollutants
(CAPs)
including
carbon
monoxide
(CO),
nitrogen
dioxide
(NO2),
particulate
matter
smaller
than
10
μm
(PM10),
ozone
(O3)
and
sulphur
(SO2)
were
studied
from
2013
to
2021
at
14
regulatory
monitoring
stations.
Results
show
that
biggest
improvements
pollution
are
for
primary
NO2
SO2,
reductions
54%
93%
respectively
period
studied.
Gross
domestic
product
(GDP),
growth
energy
consumption
significantly
negatively
correlated
SO2
strongly
positively
PM10.
CO
number
buildings
completed,
while
results
O3
inconclusive.
Trends
PM10,
indicate
these
two
decoupled
development,
supporting,
caution,
environmental
Kuznets
curve
hypothesis
relationship
between
degradation.
improvement
city's
due
effective
implementation
local
policies,
unaffected
by
large-scale
urbanization.
monthly
assessments
Dubai's
2019
2020
3–16%
COVID-related
levels
pollutants,
except
ozone,
which
increased
an
average
8%.
Ecotoxicology and Environmental Safety,
Journal Year:
2023,
Volume and Issue:
265, P. 115490 - 115490
Published: Sept. 23, 2023
Fine
particulate
matter
(PM2.5)-related
health
issues
have
received
increasing
attention
as
a
worldwide
public
problem,
and
PM2.5-related
chronic
kidney
disease
(CKD)
has
been
emerging
over
the
years.
Limited
research
focused
on
mechanism
of
PM2.5-induced
disease.
To
investigate
impact
PM2.5
its
potential
mechanism,
we
generated
PM2.5-exposed
C57BL/6
mouse
model
by
using
Shanghai
Meteorological
Environment
Animal
Exposure
System
(Shanghai-METAS)
for
12
weeks,
urine,
blood
tissues
were
collected.
The
pathological
changes
function
measured
after
exposure
weeks.
Along
with
glomerular
damage,
tubular
damage
was
also
severe
in
mice.
results
mRNA-seq
indicate
that
pyroptosis
is
involved.
Pyroptosis
defined
caspase-1-dependent
programmed
cell
death
response
to
insults.
expression
nucleotide-binding
oligomerization
domain-like
receptor
family
pyrin
domain
containing
3
(NLRP3),
Caspase-1,
gasdermin
D
(GSDMD)
IL-1β
detected.
NLRP3
inflammasome
activation
subsequent
observed
Bumpt
cells
too.
At
meantime,
inhibitors
caspase-1
applied
exposed
cells.
It
turned
out
significant
rescue
effect
inhibitors.
This
study
revealed
new
insights
into
injury
specific
well
morphological
changes,
important
role
dysfunction.
International Journal of Environmental Health Research,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 11
Published: April 29, 2025
This
study
aimed
to
assess
PM2.5
exposure
levels
in
Ahvaz,
Iran,
and
quantify
the
associated
burden
of
disease
attributable
particulate
pollution.
To
uncertainty
mortality
morbidity,
response
function
model
for
probabilistic
risk
assessment
was
used.
The
analysis
aerosol
variations
by
Aerosol
Optical
Thickness
indicated
a
decline
concentrations
during
pandemic.
During
period,
annual
mean
exceeded
limit
value
established
World
Health
Organization.
Cause-specific
mortality,
including
trachea
bronchus
lung
cancer,
stroke,
acute
lower
respiratory
infections,
also
decreased
14-28%
2020.
Restricted
activity
days
work
lost
11.8%
13.8%,
respectively,
correlating
with
concentrations.
Years
lived
disability
dropped
from
242.7
170.4
years
per
105
capita
2020
Mitigation
strategies,
green
infrastructure,
industrial
regulation,
improved
urban
planning,
are
needed
reduce
health
risks
this
highly
polluted
region.