Enabling Demonstrated Consent for Biobanking with Blockchain and Generative AI

The American Journal of Bioethics, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 16

Published: Nov. 5, 2024

Participation in research is supposed to be voluntary and informed. Yet it difficult ensure people are adequately informed about the potential uses of their biological materials when they donate samples for future research. We propose a novel consent framework which we call "demonstrated consent" that leverages blockchain technology generative AI address this problem. In demonstrated model, each donated sample associated with unique non-fungible token (NFT) on blockchain, records its metadata information planned past research, updated use sample. This accessible large language model (LLM) customized present an understandable interactive manner. Thus, our technologies track, make available, explain regarding samples.

Language: Английский

Navigating Blockchain’s Twin Challenges: Scalability and Regulatory Compliance

Blockchains, Journal Year: 2024, Volume and Issue: 2(3), P. 265 - 298

Published: July 21, 2024

Blockchain technology promises transformative potential across diverse sectors, facilitating innovations in areas ranging from finance to healthcare. Despite its many promising applications, several barriers—including scalability challenges, regulatory complexities, and technical hurdles—limit widespread adoption. This systematic literature review delves into enhancements explores the legal landscapes impacting blockchain deployment ten key sectors: IoT, healthcare, finance, education, social media, genomics, supply chain, vehicular networks, e-voting, tourism. These sectors were selected based on their significant engagement with prominence analyzed literature. We examine technological advancements such as Layer-2 techniques, sharding, consensus algorithm optimization, rollups, discuss implications for throughput, latency, compliance standards General Data Protection Regulation (GDPR). The details these developments discusses broader industry academia, emphasizing need interdisciplinary research innovation. By identifying gaps current suggesting future directions, this study serves a roadmap researchers, practitioners, policymakers develop secure, scalable, compliant systems. Our comprehensive examination provides valuable insights enhancing efficiency, security, of technology.

Language: Английский

Utilizing Blockchain Technology for Healthcare and Biomedical Research: A Review

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 21, 2024

Blockchain is a decentralized, secure, and immutable public ledger that offers significant benefits over conventional centralized systems by preventing data breaches cyber-attacks. It has great potential to improve security, privacy, interoperability in healthcare biomedical research. This review discusses the basic principles historical evolution of blockchain evaluates implications for existing infrastructure. also highlights technology's advantages electronic health records, supply chain management, clinical trials, telemedicine. However, this technology faces several hurdles, including regulatory issues, technical complexity, economic costs, which suggest gradual adoption time. In addition, emphasizes its ability ensure integrity, enhance collaboration, protect intellectual property shows can management providing efficient, patient-centric solutions. Furthermore, it future research suggests ongoing interdisciplinary approaches are essential overcoming current barriers realizing full technology. Future should focus on developing privacy-preserving hybrid storage solutions comply with international laws regulations, thus enhancing sustainability scalability healthcare.

Language: Английский