PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(5), P. e0303094 - e0303094
Published: May 20, 2024
In
response
to
the
growing
number
of
diabetes
cases
worldwide,
Our
study
addresses
escalating
issue
diabetic
eye
disease
(DED),
a
significant
contributor
vision
loss
globally,
through
pioneering
approach.
We
propose
novel
integration
Genetic
Grey
Wolf
Optimization
(G-GWO)
algorithm
with
Fully
Convolutional
Encoder-Decoder
Network
(FCEDN),
further
enhanced
by
Kernel
Extreme
Learning
Machine
(KELM)
for
refined
image
segmentation
and
classification.
This
innovative
combination
leverages
genetic
grey
wolf
optimization
boost
FCEDN’s
efficiency,
enabling
precise
detection
DED
stages
differentiation
among
types.
Tested
across
diverse
datasets,
including
IDRiD,
DR-HAGIS,
ODIR,
our
model
showcased
superior
performance,
achieving
classification
accuracies
between
98.5%
98.8%,
surpassing
existing
methods.
advancement
sets
new
standard
in
offers
potential
automating
fundus
analysis,
reducing
reliance
on
manual
examination,
improving
patient
care
efficiency.
findings
are
crucial
enhancing
diagnostic
accuracy
outcomes
management.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(5), P. e26799 - e26799
Published: Feb. 28, 2024
Computer-aided
diagnosis
(CAD)
systems
play
a
vital
role
in
modern
research
by
effectively
minimizing
both
time
and
costs.
These
support
healthcare
professionals
like
radiologists
their
decision-making
process
efficiently
detecting
abnormalities
as
well
offering
accurate
dependable
information.
heavily
depend
on
the
efficient
selection
of
features
to
accurately
categorize
high-dimensional
biological
data.
can
subsequently
assist
related
medical
conditions.
The
task
identifying
patterns
biomedical
data
be
quite
challenging
due
presence
numerous
irrelevant
or
redundant
features.
Therefore,
it
is
crucial
propose
then
utilize
feature
(FS)
order
eliminate
these
primary
goal
FS
approaches
improve
accuracy
classification
eliminating
that
are
less
informative.
phase
plays
critical
attaining
optimal
results
machine
learning
(ML)-driven
CAD
systems.
effectiveness
ML
models
significantly
enhanced
incorporating
during
training
phase.
This
empirical
study
presents
methodology
for
using
technique.
proposed
approach
incorporates
three
soft
computing-based
optimization
algorithms,
namely
Teaching
Learning-Based
Optimization
(TLBO),
Elephant
Herding
(EHO),
hybrid
algorithm
two.
algorithms
were
previously
employed;
however,
addressing
issues
predicting
human
diseases
has
not
been
investigated.
following
evaluation
focuses
categorization
benign
malignant
tumours
publicly
available
Wisconsin
Diagnostic
Breast
Cancer
(WDBC)
benchmark
dataset.
five-fold
cross-validation
technique
employed
mitigate
risk
over-fitting.
approach's
proficiency
determined
based
several
metrics,
including
sensitivity,
specificity,
precision,
accuracy,
area
under
receiver-operating
characteristic
curve
(AUC),
F1-score.
best
value
computed
through
suggested
97.96%.
clinical
decision
system
demonstrates
highly
favourable
performance
outcome,
making
valuable
tool
practitioners
secondary
opinion
reducing
overburden
expert
practitioners.
BMC Medical Informatics and Decision Making,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: Aug. 16, 2024
Abstract
Problem
Sepsis,
a
life-threatening
condition,
accounts
for
the
deaths
of
millions
people
worldwide.
Accurate
prediction
sepsis
outcomes
is
crucial
effective
treatment
and
management.
Previous
studies
have
utilized
machine
learning
prognosis,
but
limitations
in
feature
sets
model
interpretability.
Aim
This
study
aims
to
develop
that
enhances
accuracy
using
reduced
set
features,
thereby
addressing
previous
enhancing
Methods
analyzes
intensive
care
patient
MIMIC-IV
database,
focusing
on
adult
cases.
Employing
latest
data
extraction
tools,
such
as
Google
BigQuery,
following
stringent
selection
criteria,
we
selected
38
features
this
study.
also
informed
by
comprehensive
literature
review
clinical
expertise.
Data
preprocessing
included
handling
missing
values,
regrouping
categorical
variables,
Synthetic
Minority
Over-sampling
Technique
(SMOTE)
balance
data.
We
evaluated
several
models:
Decision
Trees,
Gradient
Boosting,
XGBoost,
LightGBM,
Multilayer
Perceptrons
(MLP),
Support
Vector
Machines
(SVM),
Random
Forest.
The
Sequential
Halving
Classification
(SHAC)
algorithm
was
used
hyperparameter
tuning,
both
train-test
split
cross-validation
methodologies
were
employed
performance
computational
efficiency.
Results
Forest
most
effective,
achieving
an
area
under
receiver
operating
characteristic
curve
(AUROC)
0.94
with
confidence
interval
±0.01.
significantly
outperformed
other
models
new
benchmark
literature.
provided
detailed
insights
into
importance
various
Organ
Failure
Assessment
(SOFA)
score
average
urine
output
being
highly
predictive.
SHAP
(Shapley
Additive
Explanations)
analysis
further
enhanced
model’s
interpretability,
offering
clearer
understanding
impacts.
Conclusion
demonstrates
significant
improvements
predicting
model,
supported
advanced
techniques
thorough
preprocessing.
Our
approach
key
impacting
mortality,
making
accurate
interpretable.
By
practical
utility
settings,
offer
valuable
tool
healthcare
professionals
make
data-driven
decisions,
ultimately
aiming
minimize
sepsis-induced
fatalities.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(16), P. e36112 - e36112
Published: Aug. 1, 2024
Implementing
diabetes
surveillance
systems
is
paramount
to
mitigate
the
risk
of
incurring
substantial
medical
expenses.
Currently,
blood
glucose
measured
by
minimally
invasive
methods,
which
involve
extracting
a
small
sample
and
transmitting
it
meter.
This
method
deemed
discomforting
for
individuals
who
are
undergoing
it.
The
present
study
introduces
an
Explainable
Artificial
Intelligence
(XAI)
system,
aims
create
intelligible
machine
capable
explaining
expected
outcomes
decision
models.
To
this
end,
we
analyze
abnormal
levels
utilizing
Bi-directional
Long
Short-Term
Memory
(Bi-LSTM)
Convolutional
Neural
Network
(CNN).
In
regard,
acquired
through
oxidase
(GOD)
strips
placed
over
human
body.
Later,
signal
data
converted
spectrogram
images,
classified
as
low
glucose,
average
levels.
labeled
images
then
used
train
individualized
monitoring
model.
proposed
XAI
model
track
real-time
uses
XAI-driven
architecture
in
its
feature
processing.
model's
effectiveness
evaluated
analyzing
performance
several
evolutionary
metrics
confusion
matrix.
revealed
demonstrate
that
effectively
identifies
with
elevated
Cogent Education,
Journal Year:
2025,
Volume and Issue:
12(1)
Published: Jan. 2, 2025
Early
glaucoma
detection
through
accurate
optic
disc
interpretation
is
essential
but
challenging
for
ophthalmology
residents.
This
study
evaluated
the
effectiveness
of
interactive
(ITM)
versus
non-interactive
(NITM)
web-based
training
modules
in
improving
skills
diagnosis
among
Ninety-six
residents
from
five
centers
Thailand
were
randomized
into
ITM
or
NITM
groups.
Both
groups
completed
pre-
and
post-tests
containing
30
standardized
photographs
used
self-study
with
100
images
obtained
CLARUS™
500
over
two
months.
The
group
received
immediate
feedback
on
their
answers,
while
only
viewed
correct
answers
without
interaction.
demonstrated
significant
improvement
scores
after
(P
<
0.001),
no
difference
between
=
0.231).
Third-year
showed
greater
score
compared
to
first-year
0.009).
Satisfaction
comparable
0.416).
findings
suggest
that
both
improve
residents'
ability
evaluate
glaucomatous
discs,
though
statistically
was
found
approaches.
Biomimetics,
Journal Year:
2025,
Volume and Issue:
10(1), P. 53 - 53
Published: Jan. 14, 2025
Optimization
algorithms
play
a
crucial
role
in
solving
complex
problems
across
various
fields,
including
global
optimization
and
feature
selection
(FS).
This
paper
presents
the
enhanced
polar
lights
with
cryptobiosis
differential
evolution
(CPLODE),
novel
improvement
upon
original
(PLO)
algorithm.
CPLODE
integrates
mechanism
(DE)
operators
to
enhance
PLO's
search
capabilities.
The
particle
collision
strategy
is
replaced
DE's
mutation
crossover
operators,
enabling
more
effective
exploration
using
dynamic
rate
improve
convergence.
Furthermore,
records
reuses
historically
successful
solutions,
thereby
improving
greedy
process.
experimental
results
on
29
CEC
2017
benchmark
functions
demonstrate
CPLODE's
superior
performance
compared
eight
classical
algorithms,
higher
average
ranks
faster
Moreover,
achieved
competitive
ten
real-world
datasets,
outperforming
several
well-known
binary
metaheuristic
classification
accuracy
reduction.
These
highlight
effectiveness
for
both
selection.