The Bromodomain and extra-terminal Protein Inhibitor Apabetalone ameliorates kidney injury in diabetes by regulating cholesterol accumulation and modulating the gut microbiota DOI Creative Commons
Min Wang,

Zhaohui Huang,

Yonghong Zhu

et al.

Kidney International Reports, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Associations of Dietary Live Microbes Intake and Prevalence of Prediabetes in US Adults: A Cross-Sectional Analysis DOI Creative Commons
Xiaoxu Ge,

Juan Du,

Jiajia Wang

et al.

Journal of Multidisciplinary Healthcare, Journal Year: 2025, Volume and Issue: Volume 18, P. 1135 - 1145

Published: Feb. 1, 2025

A higher dietary intake of live microbes has been shown to be associated with a range health benefits. We aimed elucidate the associations between and risk prediabetes. Adult participants from 1999-2018 US National Health Nutrition Examination Survey were included categorized into low, medium, high microbe groups based on Sanders classification system. Associations consumption prevalence prediabetes explored using univariate multivariate logistic regression, stratified analysis, sensitivity analysis. Among 28201 (mean age 45.83 years, 48.40% men, 32.78% prediabetes) included, 9761 (31.80%), 12,076 (41.42%) 6364 (26.78%) classified groups, respectively. After adjusting for all potential covariates, odds ratios 95% confidence intervals medium 0.868 (0.803-0.937) 0.891 (0.807-0.983), respectively (P trend = 0.017), low group as reference. This association is robust not affected by participant's age, sex, race, poverty-income ratio, education level, hypertension status estimated glomerular filtration rate. was found cross-sectionally linked lower in adults.

Language: Английский

Citations

1

Association of live microbes intake and risk of all-cause, cardiovascular disease, and cancer-related mortality in patients with chronic kidney disease DOI Creative Commons

Debin Chen,

Yongju Ye,

Yining Li

et al.

Renal Failure, Journal Year: 2025, Volume and Issue: 47(1)

Published: Jan. 6, 2025

Background Chronic kidney disease (CKD) is a prevalent chronic, non-communicable disease. The long-term health effects of dietary live microbes, primarily probiotics, on CKD patients remain insufficiently understood. This study aims to investigate the association between intake microbes and outcomes among individuals with CKD.

Language: Английский

Citations

0

The role of probiotics on microvascular complications of type-2 diabetes: Nephropathy and retinopathy DOI Creative Commons

Robab Sarmadi,

Hajie Lotfi, Mohammad Amin Hejazi

et al.

Journal of Cardiovascular and Thoracic Research, Journal Year: 2024, Volume and Issue: 16(2), P. 65 - 76

Published: June 25, 2024

Diabetes is a multifactorial disorder that involves several molecular mechanisms and still one of the key global health challenges with increasing prevalence incidence. Gut microbiome dysbiosis could activate recognize receptors trigger inflammation response modulation insulin sensitivity. In addition, intricate role gut microbiota in onset development T2D (Type 2 diabetes mellitus) associated microvascular complications was identified. These include diabetic nephropathy (DN) retinopathy (DR), neuropathy, cerebrovascular disorders, coronary heart disease. A recent interesting strategy to improve these probiotics administration. The safety effects against various diseases have been validated by vitro, vivo clinical studies. this review, related between microbiome, initiation, progression its common (DN DR) discussed.

Language: Английский

Citations

2

The Bromodomain and extra-terminal Protein Inhibitor Apabetalone ameliorates kidney injury in diabetes by regulating cholesterol accumulation and modulating the gut microbiota DOI Creative Commons
Min Wang,

Zhaohui Huang,

Yonghong Zhu

et al.

Kidney International Reports, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Citations

1