Current Urology Reports, Journal Year: 2024, Volume and Issue: 26(1)
Published: Oct. 8, 2024
Language: Английский
European Journal of Preventive Cardiology, Journal Year: 2024, Volume and Issue: unknown
Published: Aug. 22, 2024
Abstract Aims The benefits of achieving optimal cardiovascular health (CVH) through Life's Simple 7 (LS7) are well-documented across diverse populations. In this study, we assess the updated metrics, Essential 8 (LE8), and its association with long-term disease (CVD) outcomes mortality. Methods results We conducted a comprehensive systematic review, searching PubMed, Google Scholar, Cochrane Library, ScienceDirect from January 2022 until June 2024, focusing on studies that specifically assessed impact LE8 CVH. statistical analysis used RevMan 5.4 applied random effects model to synthesize hazard ratios (HRs) for primary secondary outcomes. This study is registered in PROSPERO (CRD42024558493). Our final comprised 34 observational studies, encompassing 1 786 664 participants aged 18–80 years, an average follow-up approximately 11.6 years. Pooled revealed statistically significant decrease risk CVD among individuals higher scores compared those lower scores, HR 0.47 (95% CI: 0.39–0.56, P < 0.00001). Higher were also associated reductions both all-cause mortality (HR: 0.54, 95% 0.43–0.69, 0.00001) CVD-related 0.37, 0.26–0.52, 0.00001. Moreover, high have 56% coronary heart 48% stroke. Conclusion has strong inverse mortality, corresponding significantly levels.
Language: Английский
Citations
5
Frontiers in Endocrinology, Journal Year: 2024, Volume and Issue: 15
Published: Oct. 28, 2024
Background Metabolic syndrome (MetS) has a close association with cardiovascular diseases. Few studies have investigated the of Life’s Essential 8 (LE8), updated measurement health (CVH), MetS. Methods The National Health and Nutrition Examination Survey (2005–2018) data was extracted. LE8 comprised 4 behaviors (diet, physical activity, nicotine exposure, sleep health) factors [body mass index (BMI), blood lipids, glucose, pressure (BP)]. total score is average metric scores (0-100), categorized into low (0–49), moderate (50–79), high CVH (80–100) levels. Multivariable logistic regression models, restricted cubic spline models stratified analyses were performed to examine relationship between Results In this study, 21,543 participants represented 146.6 million non-institutionalized U.S. adults. Following adjustment for various potential covariates, who attained [adjusted odds ratio (AOR) = 0.234, 95% CI: 0.209, 0.262] or level (AOR 0.026, 0.021, 0.032) exhibited an inverse correlation MetS risks when comparing those level. An linear dose-response also identified ( P nonlinearity > 0.05). Conclusions inversely associated risk Adhering guidelines sustain higher may be beneficial preventing
Language: Английский
Citations
3
PLoS ONE, Journal Year: 2024, Volume and Issue: 19(11), P. e0314152 - e0314152
Published: Nov. 22, 2024
Background Life’s Essential 8 (LE8) is the American Heart Association (AHA)’s recently updated assessment of cardiovascular health (CVH). Metabolic syndrome (MetS) one most common chronic noncommunicable diseases associated with CVH impairment and an increased risk mortality. However, association LE8 all-cause disease-specific mortality in MetS population remains unknown. We aimed to explore these associations a national prospective cohort study from NHANES 2005–2018. Methods The was calculated according criteria proposed by AHA, which includes behavior factor domains. scores were categorized as low (0–49), moderate (50–79), high (80–100). assessed NCEP-ATP III criteria, data obtained through linkage National Death Index database. Results 7839 participants included only 3.5% CVH. In fully adjusted models, negatively both disease (CVD) (hazard ratios [HR] 95% confidence intervals [CI] 0.978 (0.971,0.984) 0.972 (0.961,0.984), respectively, p < 0.0001). Both moderate/high significantly lower compared (both for trend <0.0001). Health behaviors had more dominant effect factors. All-cause CVD gradually decreased increasing ideal metrics. not cancer linearly mortality, whereas factors nonlinearly (plateaued after ≥50). Education kidney influenced respectively. Conclusions population, while role. Adherence higher contributes prevention excessive population.
Language: Английский
Citations
1
Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11
Published: Nov. 6, 2024
Background Hyperuricemia is a significant risk factor for various metabolic and cardiovascular conditions. Life’s Essential 8 (LE8), comprehensive measure of health promoted by the American Heart Association, may have protective role against hyperuricemia. This study aims to evaluate association between LE8 scores hyperuricemia in representative sample US adults. Methods We conducted cross-sectional using data from National Health Nutrition Examination Survey (NHANES) 2005–2018, encompassing 26,885 were calculated based on diet, physical activity, nicotine exposure, sleep health, body mass index, blood lipids, glucose, pressure. was defined as serum uric acid levels ≥7.0 mg/dL men ≥ 6.0 women. Logistic regression generalized additive models (GAMs) used analyze relationship hyperuricemia, adjusting potential confounders. Results Higher significantly associated with lower odds (OR per 10-point increase: 0.73, 95% CI: 0.72–0.75, p < 0.001). Stratified analyses revealed consistent effects across subgroups sex, age, race/ethnicity, PIR (poverty income ratio), education level, drinking status, eGFR, CVD status. GAM both confirmed linear increasing reduced risk. For example, males, OR 0.81 (95% 0.78–0.84), females, it 0.66 0.64–0.68). Conclusion The findings suggest that higher are robustly These results support promotion behaviors encapsulated mitigate Further studies needed explore causal pathways interventions.
Language: Английский
Citations
0
Current Urology Reports, Journal Year: 2024, Volume and Issue: 26(1)
Published: Oct. 8, 2024
Language: Английский
Citations
0