International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 287, P. 138593 - 138593
Published: Dec. 9, 2024
Language: Английский
Biosensors, Journal Year: 2025, Volume and Issue: 15(4), P. 222 - 222
Published: March 31, 2025
The growing demand for real-time, non-invasive, and cost-effective health monitoring has driven significant advancements in portable point-of-care testing (POCT) devices. Among these, optical biosensors have emerged as promising tools the detection of critical biomarkers such uric acid (UA) blood glucose. Different transduction methods, like fluorescence, surface plasmon resonance (SPR), colorimetric approaches, are talked about, with a focus on how sensitive, specific, they are. Despite considerable advancements, several challenges persist, including sensor stability, miniaturization, interference effects, need calibration-free operation. This review also explores issues related to cost-effectiveness, data integration, wireless connectivity remote monitoring. further examines regulatory considerations commercialization aspects biosensors, addressing gap between research developments clinical implementation. Future perspectives emphasize integration artificial intelligence (AI) healthcare improved diagnostics, alongside development wearable implantable continuous Innovative potential change way people manage their by quickly accurately measuring glucose levels. is especially true decentralized solutions grows. By critically evaluating existing work exploring limitations opportunities field, this will help guide more efficient, accessible, reliable POCT devices that can improve patient outcomes quality life.
Language: Английский
Citations
1
Lab on a Chip, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Smartphones have the potential to transform chemical and biological analysis by functioning as portable, versatile, democratized platforms for molecular diagnostics. Recent advances in optical detection devices are reviewed.
Language: Английский
Citations
0
Advances in Clinical Medicine, Journal Year: 2025, Volume and Issue: 15(02), P. 1942 - 1951
Published: Jan. 1, 2025
Language: Английский
Citations
0
Biosensors, Journal Year: 2025, Volume and Issue: 15(3), P. 192 - 192
Published: March 18, 2025
Detecting kidney function biomarkers is critical for the early diagnosis of diseases and monitoring treatment efficacy. In this work, a portable, 3D-printed colorimetric sensor platform was developed to detect key biomarkers: uric acid, creatinine, albumin. The features enclosure with integrated diffused LED lighting ensure controlled environment image acquisition. A disposable flow cell holds samples, ensuring precision minimizing contamination. relies on analysis, where reagent reacts blood serum produce color shift proportional biomarker concentration. Using smartphone, change captured, RGB values are normalized calculate concentrations based Beer-Lambert Law. system adapts variations in smartphones, brands, conditions through an adaptive calibration algorithm, flexibility accuracy. demonstrated good linear detection ranges acid (1–30 mg/dL), creatinine (0.1–20 albumin (0.1–8 g/dL), limits 1.15 mg/dL, 0.15 0.11 g/dL, respectively. These results correlated well commercial biochemistry analyzers. Additionally, Android application handle processing database management, providing user-friendly interface real-time analysis. This cost-effective shows significant potential point-of-care diagnostics remote health monitoring.
Language: Английский
Citations
0
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 287, P. 138593 - 138593
Published: Dec. 9, 2024
Language: Английский
Citations
1