
Toxics, Journal Year: 2025, Volume and Issue: 13(5), P. 348 - 348
Published: April 27, 2025
While the application of antibiotics in livestock production has undeniably propelled rapid growth animal husbandry, escalating crisis antimicrobial resistance stemming from antibiotic use poses significant threats to global public health and sustainable agricultural development. To address this critical challenge, multifaceted strategies have been implemented through coordinated policy interventions scientific innovations. This review systematically examines two pivotal dimensions: (1) evolving regulatory frameworks governing usage (2) emerging non-antibiotic alternatives, with a particular focus on their implementation mechanisms technological maturation. The analysis transnational governance encompasses comparative evolution European Union, United States, China. These paradigms control points including registration management policies, monitoring systems, integrated surveillance programs. Concerning six categories substitutes are critically evaluated: Chinese herbal formulations, plant-derived essential oils, peptides, microecological agents, acidifiers, enzyme preparations. solutions functionally categorized into prophylactic agents (enhancing disease resilience) zootechnical additives (optimizing feed efficiency). alternatives demonstrate certain efficacy alleviating challenges overuse, yet they still face multiple barriers. Further investigations warranted establish standardized evaluation protocols conduct technoeconomic feasibility assessments under commercial-scale conditions. Ultimately, resolving dilemma requires synergistic collaboration between bodies, pharmaceutical innovators, academic researchers. work emphasizes crucial interplay evidence-based policymaking advancement shaping systems.
Language: Английский