Published: Nov. 3, 2023
Language: Английский
Annals of Internal Medicine, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 20, 2025
In July 2024, the U.S. Department of Veterans Affairs (VA) and Defense (DOD) released a joint update their 2019 clinical practice guideline (CPG) for management stroke rehabilitation. This synopsis is condensed version 2024 CPG, highlighting key aspects development process describing major recommendations. The VA/DOD Evidence-Based Practice Work Group convened work group (WG) that included stakeholders conformed to Institute Medicine's tenets trustworthy CPGs. WG conducted patient focus group, developed questions, systematically searched evaluated literature (English-language publications from 1 2018 2 May 2023). GRADE (Grading Recommendations Assessment, Development Evaluation) system was used evaluate evidence. 47 recommendations along with algorithms rehabilitation in inpatient outpatient settings. Stakeholders outside reviewed CPG before approval by Group. summarizes where evidence strongest support guidelines crucial areas relevant primary care physicians: transition community (case management, psychosocial or behavioral interventions); motor therapy (task-specific practice, mirror therapy, rhythmic auditory stimulation, electrical botulinum toxin spasticity); dysphagia, aphasia, cognition (chin tuck against resistance, respiratory muscle strength training); mental health (selective serotonin reuptake inhibitor use, psychotherapy, mindfulness-based therapies treatment but not prevention depression).
Language: Английский
Citations
2
Rheumatology International, Journal Year: 2024, Volume and Issue: 44(3), P. 399 - 411
Published: Jan. 23, 2024
Language: Английский
Citations
5
Neurological Sciences, Journal Year: 2024, Volume and Issue: 45(9), P. 4399 - 4416
Published: April 11, 2024
Language: Английский
Citations
4
BMC Biology, Journal Year: 2025, Volume and Issue: 23(1)
Published: April 30, 2025
In adult mammals, including humans, neurons, and axons in the brain spinal cord are inherently incapable of regenerating after injury. Studies animals with innate capacity for regeneration providing valuable insights into mechanisms driving tissue healing. The aim this review is to summarize recent data on zebrafish neonatal mice. We infer that elucidating these understanding how why they lost mammals will contribute development strategies promote central nervous system regeneration.
Language: Английский
Citations
0
Frontiers in Neurology, Journal Year: 2025, Volume and Issue: 16
Published: May 14, 2025
Objectives This study employed Transcranial Magnetic Stimulation combined with Electroencephalography (TMS-EEG) to examine the impacts of high-frequency repetitive transcranial magnetic stimulation (rTMS) on brain activity and cognitive function in patients post-stroke impairment (PSCI), focusing changes connectivity left dorsolateral prefrontal cortex (DLPFC) across different frequency bands. Methods Twenty subacute PSCI were recruited for a 20-day rTMS treatment, consisting 10 days sham followed by actual stimulation. Clinical scale data TMS-EEG collected before treatment (Pre), after (Sham), (TMS) analyze evoked potentials (TEP), time-frequency, functional connectivity. Additionally, post hoc subgroup analysis was conducted assess impact education level, time since onset, lesion size score improvement. Results Compared Pre Sham conditions, daily living ability scores significantly improved post-rTMS. Although TEP patterns conditions similar, enhanced early amplitude DLPFC, slowed gamma oscillations, increased theta alpha bands bilateral altered between DLPFC other regions. Changes theta-band wPLI positively correlated improvements MMSE ( r = 0.465, p 0.039) MoCA 0.493, 0.027). Patients higher levels exhibited significant improvement 0.039), while onset 60–180 showed decline 0.024). Conclusion High-frequency effectively modulated regions patients, enhancing functions. within band may serve as potential biomarker patients. Education level have certain
Language: Английский
Citations
0
Frontiers in Aging Neuroscience, Journal Year: 2024, Volume and Issue: 16
Published: March 20, 2024
Objective Alzheimer’s disease (AD) is a prevalent neurodegenerative condition that significantly impacts both individuals and society. This study aims to evaluate the effectiveness of repetitive transcranial magnetic stimulation (rTMS) as treatment for AD by summarizing evidence from systematic reviews (SRs) meta-analyses (MAs). Methods SRs/MAs rTMS were collected searching Embase, Web Science, Cochrane Library, PubMed, CNKI, VIP, Sino-Med, Wanfang databases. The search was conducted database creation January 23, 2024. Methodological quality, reporting quality risk bias assessed using Assessing Quality Systematic Reviews 2 (AMSTAR-2), Risk Bias in (ROBIS) tool Preferred Reporting Items Meta-Analyses (PRISMA). In addition, outcome measures Grading Recommendations, Assessment, Development Evaluation (GRADE). Results Eight included this met inclusion criteria. Based on AMSTAR-2, 4 SRs/MA classified low while remaining deemed be very quality. PRISMA analysis revealed out 27 items reporting, 16 achieved full (100%). However, there still some deficiencies particularly related protocol registration, strategy, bias, additional analysis. ROBIS indicated only 3 had bias. GRADE assessment 6 outcomes moderate (18.75%), (50%), 10 (31.25%). Conclusion collected, appears effective improving cognitive function patients, although methodological reduces reliability conclusions overall low. based available results, we support value an intervention improve AD. future studies, it necessary confirm efficacy patients provide more reliable scientific data contribute evidence-based medicine.
Language: Английский
Citations
2
American Journal of Translational Research, Journal Year: 2024, Volume and Issue: 16(2), P. 592 - 598
Published: Jan. 1, 2024
Objective: To investigate the therapeutic efficacy of scalp acupuncture combined with repetitive transcranial magnetic stimulation (rTMS) for post-stroke cognitive impairment at different time intervals.Method: This retrospective cohort study divided patients into two groups according to timing rTMS intervention.Group A received 1 month and routine basic treatment function training months post-stroke.Group B 2 post-stroke.Both underwent assessment using Montreal Cognitive Assessment (MoCA) before ends first second post-stroke.Results: The population included 92 total stroke evenly Groups B. Group A's scores were higher end compared baseline remained stable treatment.By contrast, B's score increased by month.There no significant differences in or between groups.Conclusion: Scalp can effectively treat impairment, regardless intervention.
Language: Английский
Citations
2
Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15
Published: April 22, 2024
Objective The reliability of clinical evidence depends on high-quality meta-analyses/ systematic reviews (MAs/SRs). However, there has been no assessment the quality MAs/SRs for repetitive transcranial magnetic stimulation (rTMS) in post-stroke cognitive impairment (PSCI), both nationally and internationally. This article seeks to use radar plotting visually present rTMS improving function PSCI, aiming offer an intuitive foundation research. Methods Eight Chinese or English databases were systematically searched collect comprehensive literature, retrieval time ranged from inception 26 March 2024. Literature ranking was calculated using six dimensions: publication year, design type, AMSTAR-2 score, PRISMA bias, homogeneity. Finally, plots drafted a multivariate literature evaluation. GRADE tool assessed strength outcome indicators included MAs/SRs. Results 17 articles had average scores 12.29, 17, 9.88, 9.71, 12.88, 12.76 each dimension. plot showed that published 2023 highest rank large area, while 2021 lowest small area. evaluation revealed 51 pieces very low quality, 67 12 moderate only one high quality. Conclusion score 8.50 with higher rankings indicating greater significance reference. Variations attributed inadequate study planning, irregular search screening, insufficient description inclusion criteria studies, consideration bias risk studies. Most indicated more effective than control group enhancing global activities daily living PSCI patients. overall generally needs validation future evidence. Systematic review registration: https://www.crd.york.ac.uk/prospero/ , identifier CRD42023491280.
Language: Английский
Citations
1
Medicine, Journal Year: 2024, Volume and Issue: 103(45), P. e40227 - e40227
Published: Nov. 8, 2024
Study the treatment of poststroke depression and insomnia using varied repetitive transcranial magnetic stimulation (rTMS) frequencies alongside paroxetine. Aim to enhance rTMS effectiveness for depression, insomnia, neurological impairment, daily living skills.
Language: Английский
Citations
1
Neurorehabilitation, Journal Year: 2024, Volume and Issue: 54(4), P. 677 - 690
Published: June 18, 2024
Intermittent theta burst stimulation (iTBS) has demonstrated efficacy in patients with cognitive impairment. However, activation patterns and mechanisms of iTBS for post-stroke impairment (PSCI) remain insufficiently understood.
Language: Английский
Citations
0