Letter to the editor: “A two-center prospective cohort study of serum RIP-3 as a potential biomarker in relation to severity and prognosis after severe traumatic brain injury” DOI
Silambarasan Tamil Selvan

Neurosurgical Review, Journal Year: 2024, Volume and Issue: 47(1)

Published: Oct. 7, 2024

Language: Английский

Association of serum galectin3 levels with six-month functional outcome of severe traumatic brain injury and the mediation effect of acute lung injury: A two-center prospective cohort study DOI

Huayong Hong,

Daoping Cai, Xiaole Zhang

et al.

Clinica Chimica Acta, Journal Year: 2025, Volume and Issue: 569, P. 120189 - 120189

Published: Feb. 10, 2025

Language: Английский

Citations

0

Serum RIPK1, Acute Lung Injury, and Outcomes in Severe Traumatic Brain Injury: A Multicenter Prospective Study DOI Creative Commons

Liang Cai,

Xianghong Dou,

Wensheng Dong

et al.

Therapeutics and Clinical Risk Management, Journal Year: 2025, Volume and Issue: Volume 21, P. 385 - 405

Published: March 1, 2025

Receptor-interacting protein kinase-1 (RIPK1), a regulator of necroptosis, is involved in acute brain injury and lung (ALI). Here, serum RIPK1 levels were measured after severe traumatic (sTBI), with an endeavor to unveil its prognostic implications mediation effects ALI. In this multicenter prospective study, gauged 100 healthy individuals 158 sTBI patients need decompressive craniectomy for herniation. The collected materials encompassed the Glasgow Coma Scale (GCS), pupil enlargement status, basal cisternal shapes, ALI, etc. extended outcome scale (GOSE) was employed estimating neurological impairments at posttraumatic 180-day mark. Multifactorial analytical methods applied assess relevancies. Patients, as opposed controls, had markedly raised levels, even substantially higher those lower GCS scores, bilateral or obliterated cisterns. Using restricted cubic spline, linearly related occurrent risks four variables interest, that death, overall survival, poor prognosis (GOSE scores 1-4) independently predicted these variables. noninteractional age, sex, hypertension, diabetes, smoking alcohol habits terms association exhibited high discriminatory efficiency under receiver operating characteristic curve. via partial by associated death patients. Elevated may be highly trauma severity, outcomes ALI; ALI partially explains links between prognosis, substantializing serological predictor good prospect sTBI.

Language: Английский

Citations

0

Letter to the editor: A two-center prospective cohort study of serum RIP-3 as a potential biomarker in relation to severity and prognosis after severe traumatic brain injury DOI

Deepa Lachhman Das,

Raja Ram Khenhrani, Umer Iqbal

et al.

Neurosurgical Review, Journal Year: 2024, Volume and Issue: 47(1)

Published: Sept. 6, 2024

Language: Английский

Citations

0

“Biomarkers in severe traumatic brain injury: enhancing prognostic accuracy and therapeutic strategies” DOI

Manal Nadeem,

Umer Bin Shahzad,

Muhammad Ejaz Ahmed

et al.

Neurosurgical Review, Journal Year: 2024, Volume and Issue: 47(1)

Published: Sept. 13, 2024

Language: Английский

Citations

0

Letter to the editor: “A two-center prospective cohort study of serum RIP-3 as a potential biomarker in relation to severity and prognosis after severe traumatic brain injury” DOI
Silambarasan Tamil Selvan

Neurosurgical Review, Journal Year: 2024, Volume and Issue: 47(1)

Published: Oct. 7, 2024

Language: Английский

Citations

0