The neuroprotective potential of carbazole in traumatic brain injury

Brain Injury, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 11

Published: Dec. 18, 2024

Objective To review the neuroprotective potential of carbazole and its derivatives in management traumatic brain injury (TBI), focusing on their mechanisms action, preclinical findings, clinical applications.

Language: Английский

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The role of serotonin and serotonergic-related metabolites in pathogenesis of vasovagal syncope

Heart Rhythm, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

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Cardiac Geometry and Function in Patients with Reflex Syncope

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(22), P. 6852 - 6852

Published: Nov. 14, 2024

Reflex syncope (RS) is the most prevalent form of syncope, yet its pathophysiology and clinical presentation are not well understood. Despite controversy, ‘ventricular theory’ remains plausible hypothesis to explain RS in susceptible patients. Certain assumptions regarding geometry function heart essential supporting this theory. Given these considerations, goal review was try integrate data on morphology a phenotype patient RS. Previous research suggests that small left ventricle atria, addition normo- or hypercontractile myocardium, predispose more syncopal events. These findings have been confirmed different subsets patients, including those with chronic fatigue syndrome, highlighting common pathophysiologic pathways subgroups population. Heart seem play role treatment strategies for administration medications, pacing, possibly cardioneural ablation. In addition, parameters related chambers electrical activation predictive value recurrence. could be included future improve accuracy models

Language: Английский

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Serotonin does not seem to play a major role in eliciting vasovagal syncope

Clinical Autonomic Research, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 21, 2024

Language: Английский

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