Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles

Scientific Reports, Journal Year: 2019, Volume and Issue: 9(1)

Published: Jan. 3, 2019

Polycyclic aromatic compounds (PACs) are known due to their mutagenic activity. Among them, 2-nitrobenzanthrone (2-NBA) and 3-nitrobenzanthrone (3-NBA) considered as two of the most potent mutagens found in atmospheric particles. In present study 2-NBA, 3-NBA selected PAHs Nitro-PAHs were determined fine particle samples (PM 2.5) collected a bus station an outdoor site. The fuel used by buses was diesel-biodiesel (96:4) blend light-duty vehicles run with any ethanol-to-gasoline proportion. concentrations 2-NBA were, on average, under 14.8 µg g-1 4.39 g-1, respectively. order access main sources formation routes these compounds, we performed ternary correlations multivariate statistical analyses. for studied diesel/biodiesel exhaust followed floor resuspension. coastal site, vehicular emission, photochemical wood combustion well other PACs. Incremental lifetime cancer risk (ILCR) calculated both places, which presented low values, showing incidence although ILCR values around 2.5 times higher than from

Language: Английский

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Supramolecular Luminescent Sensors

Chemical Reviews, Journal Year: 2018, Volume and Issue: 119(1), P. 322 - 477

Published: Dec. 3, 2018

There is great need for stand-alone luminescence-based chemosensors that exemplify selectivity, sensitivity, and applicability overcome the challenges arise from complex, real-world media. Discussed herein are recent developments toward these goals in field of supramolecular luminescent chemosensors, including macrocycles, polymers, nanomaterials. Specific focus placed on development new macrocycle hosts since 2010, coupled with considerations underlying principles chemistry as well analytes interest common luminophores. State-of-the-art fields polymer nanomaterial sensors also examined, some remaining unsolved area discussed.

Language: Английский

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Sources, characteristics, toxicity, and control of ultrafine particles: An overview

Geoscience Frontiers, Journal Year: 2021, Volume and Issue: 13(1), P. 101147 - 101147

Published: Jan. 20, 2021

Air pollution by particulate matter (PM) is one of the main threats to human health, particularly in large cities where levels are continually exceeded. According their source emission, geography, and local meteorology, pollutant particles vary size composition. These conditioned aerodynamic diameter thus classified as coarse (2.5–10 μm), fine (0.1–2.5 ultrafine (<0.1 degree toxicity becomes greater for smaller particles. can get into lungs translocate vital organs due size, causing significant health consequences. Besides, PM pollutants have been linked respiratory conditions, genotoxic, mutagenic, carcinogenic activity beings. This paper presents an overview emission sources, physicochemical characteristics, collection measurement methodologies, toxicity, existing control mechanisms (UFPs) last fifteen years.

Language: Английский

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A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycyclic aromatic hydrocarbons

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 789, P. 147741 - 147741

Published: May 15, 2021

Language: Английский

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A Systematic Review of Polycyclic Aromatic Hydrocarbon Derivatives: Occurrences, Levels, Biotransformation, Exposure Biomarkers, and Toxicity

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(41), P. 15314 - 15335

Published: Sept. 13, 2023

Polycyclic aromatic hydrocarbon (PAH) derivatives constitute a significant class of emerging contaminants that have been ubiquitously detected in diverse environmental matrixes, with some even exhibiting higher toxicities than their corresponding parent PAHs. To date, compared PAHs, fewer systematic summaries and reanalyses are available for PAH great concerns. This review summarizes the current knowledge on chemical species, levels, biotransformation patterns, analytical methods, internal exposure routes representative biomarkers, toxicity derivatives, primarily focusing nitrated PAHs (NPAHs), oxygenated (OPAHs), halogenated (XPAHs), alkylated (APAHs). A collection 188 compounds from four categories, 44 NPAHs, 36 OPAHs, 56 APAHs, 52 XPAHs, has compiled 114 studies documented presence derivatives. These exhibited weighted average air concentrations varied lower limit 0.019 pg/m3 to threshold 4060 pg/m3. Different methods utilizing comprehensive two-dimensional gas chromatography coupled high-resolution time-of-flight mass spectrometry (GC × GC-TOF-MS), (GC-TOF-MS), quadrupole GC-QQQ-MS), Fourier-transform ion cyclotron resonance (FT-ICR MS), adopted untargeted strategies identification also reviewed here. Additionally, an in-depth analysis patterns each category is provided, including likelihood specific reaction types. For toxicity, we summarized key metabolic activation pathways, which could result formation reactive metabolites capable covalently bonding DNA tissue proteins, potential health outcomes such as carcinogenicity genotoxicity, oxidative stress, inflammation immunotoxicity, developmental might be mediated by aryl receptor (AhR). Finally, pinpoint research challenges emphasize need further identifying tracking external evaluating levels associated clarifying routes, considering mixture effects. aims provide broad understanding derivatives' identification, occurrence, human exposure, biotransformation, offering valuable reference guiding future this underexplored area.

Language: Английский

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Determination of hydroxy derivatives of PAHs in sewage sludge by GC-MS/MS

Desalination and Water Treatment, Journal Year: 2025, Volume and Issue: unknown, P. 101015 - 101015

Published: Jan. 1, 2025

Language: Английский

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Estimation of public exposure to PAH and environmental risks via wastewater-based epidemiology

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 292, P. 117920 - 117920

Published: Feb. 22, 2025

Language: Английский

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Trends of research on polycyclic aromatic hydrocarbons in food: A 20-year perspective from 1997 to 2017

Trends in Food Science & Technology, Journal Year: 2018, Volume and Issue: 83, P. 86 - 98

Published: Nov. 13, 2018

Language: Английский

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Biofuels and renewable chemicals production by catalytic pyrolysis of cellulose: a review

Environmental Chemistry Letters, Journal Year: 2020, Volume and Issue: 18(5), P. 1625 - 1648

Published: June 19, 2020

Language: Английский

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In vitro evaluation of organic extractable matter from ambient PM2.5 using human bronchial epithelial BEAS-2B cells: Cytotoxicity, oxidative stress, pro-inflammatory response, genotoxicity, and cell cycle deregulation

Environmental Research, Journal Year: 2019, Volume and Issue: 171, P. 510 - 522

Published: Jan. 31, 2019

Language: Английский

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