International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 13135 - 13148
Published: Dec. 1, 2024
Skin
radiation
damage
is
a
prevalent
form
of
tissue
injury
encountered
during
radiotherapy,
accidents,
and
occupational
exposure.
The
only
clinically
approved
radioprotective
agent,
amifostine,
associated
with
numerous
side
effects,
underscoring
the
urgent
need
for
development
safe
effective
agents.
Natural
products
reductive
properties
possess
high
antioxidant
activity
biocompatibility,
but
their
low
bioavailability
limits
efficacy
clinical
application.
To
address
this,
we
utilized
epigallocatechin
gallate
(EGCG)
as
model
compound
employed
nanotechnology
to
enhance
cellular
uptake
natural
compounds,
thereby
improving
free
radical
scavenging
capabilities.
Ultraviolet
(UV)
irradiation
is
dangerous
and
can
cause
serious
skin
diseases
if
excessively
exposed
to
it.
Thus,
it
highly
desirable
for
human
health
monitor
the
UV
radiation
intensity.
In
this
report,
a
flexible
stretchable
dual-response
detector
reported
by
integrating
UV-responsive
color-switchable
WO3
quantum
dots
(QDs)
with
an
electrical
hydrogel.
With
intensity
of
increasing
from
0.5
10
mW/cm2,
color
hydrogel
switched
dark
blue
gradually
due
excellent
photochromic
property
QDs
radiation.
Furthermore,
linear
relationship
be
established
between
difference
Hence,
under
solar
used
estimate
in
daily
life.
addition,
when
greater
than
converts
colorimetric
response
into
resistance
change.
its
properties
irradiation,
prepared
provides
idea
developing
novel
detection
instruments.
Polymer Engineering and Science,
Journal Year:
2024,
Volume and Issue:
64(9), P. 4246 - 4257
Published: June 27, 2024
Abstract
The
purpose
of
UV
sensors
is
to
detect
ultraviolet
radiation,
which
crucial
for
various
applications,
such
as
skin
protection,
environmental
monitoring,
and
industrial
processes
where
exposure
poses
risks.
These
provide
real‐time
data
ensure
safety
optimize
performance
in
relevant
fields.
In
this
context,
the
aim
study
was
develop
easy‐to‐use
using
photochromic
nanofibrous
materials.
Photochromic
nanofibers
were
obtained
by
electrospinning
thermoplastic
polyurethane
a
spirooxazine
dye.
Two
solvent
systems
(only
dimethylformamide
dimethylformamide:dichloromethane
mixture)
three
dye
concentrations
(0.5%,
2%,
5%)
used
produce
nanofibers.
Uniform
bead‐free
system.
fatigue
resistance
tested,
revealing
maximum
color
loss
14%
after
20
on‐off
cycles.
Nanofibers
produced
with
system
0.5%
concentration
chosen
sensor
design
due
their
high
total
difference.
served
indicators,
grayscale‐
adapted
scale
evaluation.
A
prototype
capable
accurately
determining
levels
successfully
developed
This
spectrally
selective
can
offer
remarkable
potential
managing
impact
UVR
our
day‐to‐
day
life.
Highlights
Bead‐free,
uniform
DMF:DCM
returned
original
colorless
state
5
min.
showed
resistance.
nanofiber
indicated
intensity
comparing
via
grayscale.
Foods,
Journal Year:
2025,
Volume and Issue:
14(6), P. 996 - 996
Published: March 14, 2025
Propolis
demonstrates
diverse
pharmacological
properties
encompassing
antimicrobial,
anti-inflammatory,
antioxidant,
immunomodulatory,
and
wound-healing
activities.
This
study
investigated
the
therapeutic
mechanism
of
propolis
against
ultraviolet
(UV)-induced
allergic
dermatitis
through
an
integrated
approach
combining
network
pharmacology
with
in
vitro
experimental
validation.
The
targets
components
were
conducted
PubChem,
EMBL-EBI,
SEA
Search
Server
databases,
disease-associated
for
atopic
related
conditions
extracted
from
GeneCards.
overlapping
between
UV-induced
screened.
Gene
Ontology
(GO)
Enrichment
analysis
Kyoto
Encyclopedia
Genes
Genomes
(KEGG)
pathway
enrichment
performed.
key
further
validated
ELISA
experiments
using
HSF
cells.
results
show
that
there
28
dermatitis.
GO
1246
terms
biological
functions,
52
cellular
components,
98
molecular
functions.
KEGG
obtained
110
signaling
pathways.
protein-protein
interaction
(PPI)
showed
TNF,
NFKB1,
MMP-9,
IL-2
hub
proteins.
experiment
confirmed
reduced
levels
MMP-9
UBV-induced
cells
a
dose-dependent
manner.
These
findings
provide
mechanistic
evidence
supporting
as
promising
functional
food,
dietary
supplements,
or
medicinal
agent
skin
disorders.
Environmental Microbiology Reports,
Journal Year:
2025,
Volume and Issue:
17(1)
Published: Jan. 16, 2025
ABSTRACT
Mycosporine‐like
amino
acids
are
water‐soluble
secondary
metabolites
that
protect
photosynthetic
microorganisms
from
ultraviolet
radiation.
Here,
we
present
direct
evidence
for
the
production
of
these
compounds
in
surface
scums
cyanobacteria
along
Baltic
Sea
coast.
We
collected
59
environmental
samples
southern
coast
Finland
during
summers
2021
and
2022
analysed
them
using
high‐resolution
liquid
chromatography‐mass
spectrometry.
Our
results
revealed
presence
microbial
sunscreens
nearly
all
scum
samples.
synthesised
through
coordinated
action
four
biosynthetic
enzymes
encoded
a
compact
pathway.
Bioinformatics
analysis
mysB
gene
indicated
responsible
belonged
to
Anabaena
/
Dolichospermum
Aphanizomenon
species
complex.
mapped
distribution
onto
phylogenomic
tree,
utilising
120
bacterial
single‐copy
conserved
genes
101
draft
or
complete
genomes
within
This
showed
48%
identified
possess
ability
produce
compounds,
with
pathways
being
most
common
strains.
detected
porphyra‐334
shinorine,
two
widely
reported
family
members,
strains
isolated
Gulf
Finland's
layer.
The
estimated
content
sp.
UHCC
0684
was
7.4
mg
per
gram
dry
weight.
suggest
bloom‐forming
could
be
potential
source
cosmetic
biotechnological
applications
may
play
significant
role
cyanobacterial
bloom
formation.
