COVID-19 Vaccination and Transient Increase in CD4/CD8 Cell Counts in People with HIV: Evidence from China DOI Creative Commons
Yanyan Li,

Yingying Lin,

Yunyun Yi

et al.

Vaccines, Journal Year: 2024, Volume and Issue: 12(12), P. 1365 - 1365

Published: Dec. 3, 2024

Objectives: Accumulating evidence has confirmed the efficacy and safety of COVID-19 vaccines against SARS-CoV-2 infection. However, effect vaccination on immuno-virological parameters in people with HIV (PWH) is uncertain. Methods: A total 372 PWH treated at Beijing Ditan Hospital were included. Unvaccinated matched 1:3 vaccinated using a propensity score matching algorithm. Differences markers between groups analyzed. The Wilcoxon signed rank test was used to for changes CD4 CD8 counts viral load over two months around vaccination. In addition, we investigated long-term HIV-related different dose entire population. Results: Vaccinated had higher CD4/CD8 ratio (0.64 (0.49, 0.78) vs. 0.80 (0.56, 1.03), p = 0.037) than unvaccinated within two-month window after third dose. There 337 who received vaccination, 73.9% (n 249) three doses vaccine. We observed transient increase count especially second (CD4 count: 583.5 (428.5, 706.8) 618.0 (452.0, 744.0), 0.018; ratio: 0.70 (0.50, 0.91) 0.71 (0.53, 0.96), < 0.001)) 575.5 (435.5, 717.0) 577.5 (440.8, 754.8), 0.001; (0.52, 0.93) 0.79 1.00), 0.001)). Recent ratios lower but remained before PWH. no negative load. Conclusions: enhanced cellular immune response induced by may diminish time return normal levels. adverse

Language: Английский

“I’m Afraid to Put Any More of It Into My Body”: COVID-19 Vaccination and Booster Barriers and Facilitators Among People with HIV in South Carolina DOI Creative Commons
Camryn Garrett, Arielle N’Diaye, Shan Qiao

et al.

AIDS and Behavior, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Language: Английский

Citations

0
Mapping Vaccination Mindsets among UK Residents of Black Ethnicities with HIV: Lessons from COVID-19 DOI Creative Commons
Zoe Moon, Lucy Campbell, Zoë Ottaway

et al.

AIDS and Behavior, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

Abstract Vaccine hesitancy is a leading threat to public health, but little known about the beliefs and mindsets that drive vaccine hesitancy, especially among people of Black ethnicities. This study aimed understand related their relationship with SARS-CoV-2 uptake in UK residents ethnicities living HIV. Adults self-reported HIV were recruited at 12 clinics England. Participants completed questionnaires clinic, including an adapted version Beliefs Medicines Questionnaire (BMQ) assess Necessity Concerns vaccine. vaccination status was ascertained through self-report shared care records. A total 863 participants enrolled between June 2021 October 2022, most whom (92%) had received least one dose SARS CoV-2 After adjusting for age region birth, higher perceived need (OR = 2.39, 95% CI 1.51–3.81), fewer concerns 0.16, 0.08–0.30), weaker endorsement COVID-19 Conspiracy 0.31, 0.19–0.50) associated uptake. Being born outside sub-Saharan Africa reduced odds being vaccinated. shows importance specific driving Further studies should explore role these influencing other vaccinations, work key stakeholders how address improve populations.

Language: Английский

Citations

0
Determinants of COVID-19 Vaccine Uptake Among People Living with Human Immunodeficiency Virus DOI Creative Commons
Gaukhar Mergenova, Alissa Davis, Susan L. Rosenthal

et al.

Journal of the International Association of Providers of AIDS Care (JIAPAC), Journal Year: 2025, Volume and Issue: 24

Published: April 1, 2025

Background Human immunodeficiency virus (HIV) cases are rising in Central Asia and Kazakhstan. People living with HIV (PLWH) Kazakhstan at heightened risk of severe COVID-19. We conducted a study to evaluate determinants COVID-19 vaccine uptake among PLWH Methods In this cross-sectional study, 196 were recruited from the Almaty City AIDS Center (July 2022-January 2023). used logistic regression how multilevel factors associated Results non-uptake was higher stigma scores (AOR = 1.08, 95%CI:1.02,1.16, P 0.017), lower level education 2.53, 95%CI: 1.04,6.17, 0.0412), never receiving flu 15.64, 95%CI:3.66,66.89, 0.0002). Participants least mild anxiety symptoms 0.15, 95%CI:0.03,0.64, 0.0107) positive attitude towards vaccination 0.79, 0.73,0.86, < 0.0001) less likely remain unvaccinated against Conclusions campaigns should be tailored for incorporate reduction interventions within healthcare settings.

Language: Английский

Citations

0
PREVALENCE AND CORRELATES OF SARS-COV-2 VACCINE UPTAKE AND HESITANCY AMONG PEOPLE WITH HIV ACROSS THE U.S. DOI
Matthew A. Spinelli, Mallory O. Johnson, Nadra E. Lisha

et al.

JAIDS Journal of Acquired Immune Deficiency Syndromes, Journal Year: 2024, Volume and Issue: unknown

Published: June 6, 2024

People with HIV (PWH) have higher risk of COVID-19 mortality. SARS-CoV-2 vaccination is highly effective among PWH, although vaccine hesitancy could limit the population-level impact.

Language: Английский

Citations

0
Factors Associated with Vaccination Adequacy in People Living with HIV: A Cross-Sectional Study DOI Creative Commons
Larissa Gerin, Andrey Oeiras Pedroso, Marcela Antonini

et al.

Vaccines, Journal Year: 2024, Volume and Issue: 12(9), P. 1003 - 1003

Published: Sept. 1, 2024

People living with HIV (PLHIV) are at greater risk of illness and death from vaccine-preventable diseases. This study aimed to identify the predictors associated recommended vaccination schedule for this group. was a single-center cross-sectional conducted in large Brazilian municipality, evaluating statuses 645 PLHIV nine immunizers. The primary outcome adequacy schedule. status assessed diphtheria/tetanus, hepatitis B, A, measles/mumps/rubella, yellow fever, 13- 23-valent pneumococcal, meningococcal C, HPV vaccines. Those who had received all vaccinations accordance established by government time assessment, without any delays, were classified as having an “adequate schedule”. independent variables included sociodemographic, clinical–epidemiological, social vulnerability factors, analyzed multiple logistic regression adjusted odds ratios (ORs) 95% confidence intervals (95% CIs). Only 47 individuals (7.3%) adequate vaccines highest rate diphtheria tetanus (533; 82.6%), one lowest measles/mumps/rubella (MMR) (243; 37.7%). main complete age group, place clinical follow-up, where they their last doses Educational interventions health professionals needed improve coverage

Language: Английский

Citations

0
Confidence on COVID-19 vaccine and its associated factors among people living with HIV: a cross-sectional survey in selected regions of Tanzania DOI Creative Commons

Anelisa Martin Rushaigo,

Johnson Mshiu, Felix Christopher Alexander

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 21(1)

Published: Oct. 29, 2024

Several vaccines were introduced in Tanzania to combat the COVID-19 pandemic. While studies have explored acceptability and hesitancy of within general population, there is limited research focusing on confidence associated factors among People Living with HIV (PLHIV). This study aims fill that gap by investigating vaccine its determinants this demographic group. A cross-sectional was conducted centres for care treatment four regions mainland using structured questionnaires. generalized linear mixed model fitted determine vaccine. total 1,100 participants interviewed; 761 (69.2%) female. The mean age standard deviation 41.6 ±12.1 years. overall level 55.3%. Females less likely express compared males (aOR = 0.77; 95% CI: 0.72–0.84). Participants primary 1.79; 1.65–1.94), secondary 1.81; 1.57–2.09), university-level education 2.14; 0.17–26.54) more report vaccines. Attending a dispensary-level health facility 1.32; 1.27–1.38) living rural areas 1.43; 1.23–1.66) significantly Although no longer global public threat, these findings highlight significance being prepared necessity continuous efforts comprehend enhance acceptance people HIV. By tackling impact attitudes group, we can improve our preparedness future challenges where uptake may once again become crucial.

Language: Английский

Citations

0
COVID-19 Vaccination and Transient Increase in CD4/CD8 Cell Counts in People with HIV: Evidence from China DOI Creative Commons
Yanyan Li,

Yingying Lin,

Yunyun Yi

et al.

Vaccines, Journal Year: 2024, Volume and Issue: 12(12), P. 1365 - 1365

Published: Dec. 3, 2024

Objectives: Accumulating evidence has confirmed the efficacy and safety of COVID-19 vaccines against SARS-CoV-2 infection. However, effect vaccination on immuno-virological parameters in people with HIV (PWH) is uncertain. Methods: A total 372 PWH treated at Beijing Ditan Hospital were included. Unvaccinated matched 1:3 vaccinated using a propensity score matching algorithm. Differences markers between groups analyzed. The Wilcoxon signed rank test was used to for changes CD4 CD8 counts viral load over two months around vaccination. In addition, we investigated long-term HIV-related different dose entire population. Results: Vaccinated had higher CD4/CD8 ratio (0.64 (0.49, 0.78) vs. 0.80 (0.56, 1.03), p = 0.037) than unvaccinated within two-month window after third dose. There 337 who received vaccination, 73.9% (n 249) three doses vaccine. We observed transient increase count especially second (CD4 count: 583.5 (428.5, 706.8) 618.0 (452.0, 744.0), 0.018; ratio: 0.70 (0.50, 0.91) 0.71 (0.53, 0.96), < 0.001)) 575.5 (435.5, 717.0) 577.5 (440.8, 754.8), 0.001; (0.52, 0.93) 0.79 1.00), 0.001)). Recent ratios lower but remained before PWH. no negative load. Conclusions: enhanced cellular immune response induced by may diminish time return normal levels. adverse

Language: Английский

Citations

0