Exploring the therapeutic potentials of bidentate ligands derived from benzohydrazide and their mononuclear transition metal complexes: insights from computational studies

Research on Chemical Intermediates, Journal Year: 2024, Volume and Issue: 50(8), P. 3915 - 3936

Published: June 25, 2024

Language: Английский

---

Exploring antimalarial and antioxidant properties of hydrazone ligands and their transition metal complexes: Insights through molecular docking and ADMET studies

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 168, P. 112917 - 112917

Published: July 27, 2024

Language: Английский

---

Unveiling the bioactive potential of organotin(IV) complexes of hydrazones: synthesis, spectral characterization, in vitro and in silico exploration

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1321, P. 139955 - 139955

Published: Sept. 7, 2024

Language: Английский

---

Experimental and computational evaluation of anti-malarial and antioxidant potential of transition metal (II) complexes with tridentate schiff base derived from pyrrolopyrimidine

BioMetals, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

Language: Английский

---

Crystal Structure, Hirshfeld Surface Analysis, and Computational Insights into Phenoxyacetohydrazones: Hydrogen-Bonded Dimers and p-Stacking Interactions.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: 1333, P. 141752 - 141752

Published: Feb. 16, 2025

Language: Английский

---

Organotin(IV) complexes: Emerging Frontiers in anticancer therapeutics and bioimaging applications

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216582 - 216582

Published: March 13, 2025

Language: Английский

---

Exploring the antimicrobial, antioxidant efficacies and computational studies of tridentate ligands derived from xanthene Schiff base and their mononuclear diorganotin(IV) complexes

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114543 - 114543

Published: April 1, 2025

Language: Английский

---

Syntheses, structures, in vitro cytostatic activity and antifungal activity evaluation of six organotin(IV) complexes based on Quinoline-6-carboxylic acid

Journal of Organometallic Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 123685 - 123685

Published: April 1, 2025

Language: Английский

---

Organotin(IV) complexes of tridentate (ONO) hydrazone ligands: synthesis, spectral characterization, antituberculosis, antimicrobial, anti-inflammatory, molecular docking and cytotoxicity studies

BioMetals, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 7, 2024

Language: Английский

---

Synthesis and Structural Characterization of Four Bidentate Ortho‐Hydroxy Schiff Bases and Their Copper (II) Complexes: Evaluation of Biological Activities, Antioxidant Power, and Molecular Docking Studies

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(2)

Published: Jan. 12, 2025

ABSTRACT Four ortho‐hydroxy aromatic bidentate Schiff bases were synthesized along with the corresponding copper (II) complexes and characterized by various analytical methods. The spatial configurations of metal suggested in light results obtained. Antibacterial evaluations revealed that ligands more active than their Cu(II) complexes. study antifungal activity showed fungus Candida albicans was inhibited (HL 3 HL 4 ) (IZ = 25 mm). According to evaluation antioxidant potency DPPH method, only ligand demonstrated a comparatively low ability scavenge free radicals compared ascorbic acid reference. Using AutoDock 4.2 program, molecular docking investigations conducted aim predicting structure–activity relationship for antibacterial qualities. sites receptor proteins, evaluated assays. A good correlation found between experimental data.

Language: Английский

---