Bridging Models DOI

Melinda Bonnie Fagan

Oxford University Press eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 153 - 193

Published: April 1, 2025

Abstract This chapter applies the framework from Part I to interdisciplinary explanation (IDE), continuing argument Chapter 4. first reprise social action framework, then apply it late-stage low-degree IDE (Section 5.1). Section 5.2 explicates three-layer structure of collective intention for this case. The result is a set coherence requirements IDE, analogous norms collaborating agents. titular bridge affords mutual relation between models contributed by different specializations. New elements comprising bridge, spanning near and far sides, reciprocally connect in opposite directions. 5.3 illustrates these with detailed example: array life science concerning hemoglobin. example extends bridging account more complex, realistic projects. 5.4 begins articulate epistemic significance models, task continued 6. 5.5 concludes summary results so far.

Language: Английский

Biological Autonomy DOI

Alvaro Moreno Bergareche,

Matteo Mossio

History, philosophy and theory of the life sciences, Journal Year: 2015, Volume and Issue: unknown

Published: Jan. 1, 2015

Language: Английский

Citations

271

From allostatic agents to counterfactual cognisers: active inference, biological regulation, and the origins of cognition DOI Open Access
Andrew W. Corcoran, Giovanni Pezzulo, Jakob Hohwy

et al.

Biology & Philosophy, Journal Year: 2020, Volume and Issue: 35(3)

Published: April 29, 2020

Language: Английский

Citations

114

Chemical roots of biological evolution: the origins of life as a process of development of autonomous functional systems DOI Creative Commons
Kepa Ruiz‐Mirazo, Carlos Briones, Andrés de la Escosura

et al.

Open Biology, Journal Year: 2017, Volume and Issue: 7(4), P. 170050 - 170050

Published: April 1, 2017

In recent years, an extension of the Darwinian framework is being considered for study prebiotic chemical evolution, shifting attention from homogeneous populations naked molecular species to heterogeneous, compartmentalized and functionally integrated assemblies molecules. Several implications this shift perspective are analysed in critical review, both terms individual units, which require adequate characterization as self-maintaining systems with internal organization, also relation their collective long-term evolutionary dynamics, based on competition, collaboration selection processes among those complex individuals. On these lines, a concrete proposal set control mechanisms that must be coupled bring about autonomous functional systems, at interface between chemistry biology, provided.

Language: Английский

Citations

96

Theoretical principles for biology: Organization DOI
Matteo Mossio, Maël Montévil,

Giuseppe Longo

et al.

Progress in Biophysics and Molecular Biology, Journal Year: 2016, Volume and Issue: 122(1), P. 24 - 35

Published: Aug. 11, 2016

Language: Английский

Citations

91

The drive to eat in homo sapiens: Energy expenditure drives energy intake DOI
John E. Blundell, Catherine Gibbons, Kristine Beaulieu

et al.

Physiology & Behavior, Journal Year: 2020, Volume and Issue: 219, P. 112846 - 112846

Published: Feb. 18, 2020

Language: Английский

Citations

89

Grounding cognition: heterarchical control mechanisms in biology DOI Creative Commons
William Bechtel, Leonardo Bich

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2021, Volume and Issue: 376(1820), P. 20190751 - 20190751

Published: Jan. 25, 2021

We advance an account that grounds cognition, specifically decision-making, in activity all organisms as autonomous systems must perform to keep themselves viable—controlling their production mechanisms. Production mechanisms, we characterize them, activities such procuring resources from environment, putting these use construct and repair the organism's body moving through environment. Given variable nature of environment continual degradation organism, mechanisms be regulated by control select when a is required how it should carried out. To operate on need procure information measurement processes evaluate possible actions. They are making decisions. In organisms, decisions made multiple different organized not hierarchically but heterarchically. many cases, they employ internal models features with which organism deal. Cognition, form thus fundamental living This article part theme issue ‘Basal cognition: conceptual tools view single cell’.

Language: Английский

Citations

62

Systems theory, thermodynamics and life: Integrated thinking across ecology, organization and biological evolution. DOI
Keith R. Skene

Biosystems, Journal Year: 2024, Volume and Issue: 236, P. 105123 - 105123

Published: Jan. 19, 2024

Language: Английский

Citations

15

Understanding Multicellularity: The Functional Organization of the Intercellular Space DOI Creative Commons
Leonardo Bich, Thomas Pradeu, Jean‐François Moreau

et al.

Frontiers in Physiology, Journal Year: 2019, Volume and Issue: 10

Published: Sept. 18, 2019

The aim of this paper is to provide a theoretical framework understand how multicellular systems realise functionally integrated physiological entities by organising their intercellular space. From perspective centred on physiology and integration, biological are often characterised as organised in such way that they metabolic self-production self-maintenance. existence activity components rely the network continuous management exchange matter energy with environment. One virtues organismic approach focused organisation it can an understanding into coherent wholes. Organismic frameworks have been primarily developed focusing unicellular life. Multicellularity, however, presents additional challenges our systems, related cells capable live together higher-order entities, some features behaviours constrained controlled system realise. Whereas most accounts multicellularity focus cell differentiation increase size main elements at level organisation, we argue these factors insufficient physically system. Our thesis one fundamental principles multicellularity, which missing or underdeveloped current accounts, functional In view, capability be space plays central role context, enables size, even specialised functions immunity. We extracellular matrix crucial active respect, evolutionary ancient specific (non-cellular) control subsystem contributes specification modulate fate behaviour. also analyse exert upon internal movement communication. Finally, show involved failures aging cancer.

Language: Английский

Citations

69

Contrasting theories of life: Historical context, current theories. In search of an ideal theory DOI Creative Commons
Athel Cornish‐Bowden,

Marı́a Luz Cárdenas

Biosystems, Journal Year: 2019, Volume and Issue: 188, P. 104063 - 104063

Published: Nov. 9, 2019

Language: Английский

Citations

66

Is defining life pointless? Operational definitions at the frontiers of biology DOI
Leonardo Bich, Sara Green

Synthese, Journal Year: 2017, Volume and Issue: 195(9), P. 3919 - 3946

Published: April 18, 2017

Language: Английский

Citations

65