The impact of varying sizes of silver nanoparticles on the induction of cellular damage in Klebsiella pneumoniae involving diverse mechanisms DOI Creative Commons
Ramesa Shafi Bhat, Mona Alonazi, Abeer Al‐Dbass

et al.

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract Silver nanoparticles (AgNPs) are extensively studied as potent antibacterial agents targeting antibiotic-resistant pathogens. Cellular damage induced through various mechanisms that can affect multiple cell components like the outer membrane, enzymes, and proteins is closely linked to their chemical morphological characteristics. We investigated impact of AgNPs’ size on effectiveness using two differently sized nanoparticles: silver nanoparticle- Citrus limon (AgCL) with an average 21 nm sinensis (AgCS) 13 nm, derived from C. environmentally friendly methods. The study evaluated effects by assessing morphology changes via scanning electron microscopy, metabolic alterations Fourier transform infrared (FT-IR) spectroscopy, oxidative stress responses biochemical markers in Klebsiella pneumoniae cells exposed AgNPs. results showed both AgCL AgCS exhibited remarkable activity, evidenced inhibition zones 14 ± 1.5 16 1.0 mm, respectively. Morphological K. treated AgNPs were dependent, notable noted. FT-IR spectroscopy revealed concentration-dependent changes, particularly shifts functional groups involved fluidity wall lipid, protein structure. Exposure led increased lipid peroxides reduced levels enzymatic non-enzymatic antioxidants, more prominently observed smaller (13 nm). induce strains, demonstrating greater efficacy. These findings underscore importance nanoparticle optimizing properties against

Language: Английский

Fruit derived silver nanoparticles synthesis for beginners – a review DOI Creative Commons
Linh Doan,

Nam N. Lam,

Khoa Tran

et al.

Nanocomposites, Journal Year: 2024, Volume and Issue: 11(1), P. 20 - 51

Published: Dec. 28, 2024

The rise of antimicrobial resistance (AMR), particularly in pathogens like Salmonella Enterica (SE), Pseudomonas Aeruginosa (PA), Staphyloccocus Aureus (SA), Escheria Coli (EC), and Klebsiella Pneumonia (KP), has led to a critical need for alternative treatments. This review introduces the green synthesis silver nanoparticles (AgNPs) using fruit extracts as sustainable environmentally friendly approach address AMR. mechanisms AMR, overview different AgNP methods, especially bioactive compounds from plant materials, characterization factors (i.e. solvents, temperature, pH, precursor concentrations), comparison activities fruit-derived AgNPs were discussed. Additionally, future research directions focus on developing scalable, cost-effective processes, exploring synergistic effects with antibiotics, addressing challenges nanoparticle size control, stability, potential cytotoxicity.

Language: Английский

Citations

1
Synthesis and Antimicrobial Activity of Newly Synthesized Nicotinamides DOI Creative Commons

Bojana Anić Marković,

Аleksandar Marinković, Jelena Antić‐Stanković

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(8), P. 1084 - 1084

Published: Aug. 18, 2024

Antioxidants are promising compounds with antimicrobial activity against drug-resistant pathogens, especially when combined conventional antimicrobials. Our study aimed to characterize the structure of nicotinamides synthesized from nicotinic acid and thiocarbohydrazones evaluate their antibacterial antifungal activity. Seven hydrazides (NC

Language: Английский

Citations

0
Sol–gel auto-combustion synthesis of ZnO nanoparticles fabricated with Eucalyptus honey and Longan honey as combustion fuels for water treatment DOI
M. Narasimha Murthy, M. Gopi Krishna,

G. Chandrakala

et al.

Chemical Papers, Journal Year: 2024, Volume and Issue: 79(1), P. 109 - 122

Published: Nov. 14, 2024

Language: Английский

Citations

0
Biosynthesis of Chitosan Nanocomposite with Myrrh-Mediated Nanosilver for Controlling Skin Pathogenic Microbes DOI Creative Commons

Hager A. Saad,

Mona Assas,

Asmaa Abdella

et al.

Natural Product Communications, Journal Year: 2024, Volume and Issue: 19(11)

Published: Nov. 1, 2024

Background: The usages of biosynthesized nanomaterials for microbial pathogens’ fighting have numerous rationales and effectiveness. Skin microbes could acquire drug-resistance that needs innovative approaches overcoming. Objectives: Phytosynthesized silver nanoparticles (AgNPs) with Commiphora myrrh resin extract (MR) their nanoconjugates chitosan (Cht) were fabricated assessed as potential antimicrobial agents controlling antibiotic-resistant skin pathogens, Materials methods: AgNPs biosynthesis was achieved within MR solution they composited Cht. syntheses validated using infrared spectroscopy electron microscopy loaded onto cotton textiles, then all nanomaterials/textiles inhibiting pathogens Staphylococcus aureus Candida albicans. Results: Nanomaterials’ characterization appointed the mean size MR-synthesized to be 22.58 nm, whereas diameter Cht/MR/AgNPs nanocomposites 130.34 nm carry +25.9 mV charges. assessment interactions between employed materials. textiles MR/AgNPs effectively inhibit growth albicans, most powerful. scanning confirmed action toward pathogens; mostly lysed deformed 12 h exposure nanocomposites. Conclusions: nanocomposite provided potent actions pathogens.

Language: Английский

Citations

0
The impact of varying sizes of silver nanoparticles on the induction of cellular damage in Klebsiella pneumoniae involving diverse mechanisms DOI Creative Commons
Ramesa Shafi Bhat, Mona Alonazi, Abeer Al‐Dbass

et al.

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract Silver nanoparticles (AgNPs) are extensively studied as potent antibacterial agents targeting antibiotic-resistant pathogens. Cellular damage induced through various mechanisms that can affect multiple cell components like the outer membrane, enzymes, and proteins is closely linked to their chemical morphological characteristics. We investigated impact of AgNPs’ size on effectiveness using two differently sized nanoparticles: silver nanoparticle- Citrus limon (AgCL) with an average 21 nm sinensis (AgCS) 13 nm, derived from C. environmentally friendly methods. The study evaluated effects by assessing morphology changes via scanning electron microscopy, metabolic alterations Fourier transform infrared (FT-IR) spectroscopy, oxidative stress responses biochemical markers in Klebsiella pneumoniae cells exposed AgNPs. results showed both AgCL AgCS exhibited remarkable activity, evidenced inhibition zones 14 ± 1.5 16 1.0 mm, respectively. Morphological K. treated AgNPs were dependent, notable noted. FT-IR spectroscopy revealed concentration-dependent changes, particularly shifts functional groups involved fluidity wall lipid, protein structure. Exposure led increased lipid peroxides reduced levels enzymatic non-enzymatic antioxidants, more prominently observed smaller (13 nm). induce strains, demonstrating greater efficacy. These findings underscore importance nanoparticle optimizing properties against

Language: Английский

Citations

0