Cardiometabolic Crossroads: Obesity, Sleep-Disordered Breathing, and Epicardial Adipose Tissue in Heart Failure with Preserved Ejection Fraction – A Mini-Review
Heart and Mind,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 11, 2024
Abstarct
Obesity,
a
multifaceted
metabolic
disorder,
stands
out
as
significant
risk
factor
in
the
development
of
heart
failure
with
preserved
ejection
fraction
(HFpEF).
Its
involvement
HFpEF
pathogenesis
encompasses
complex
interplay
adipose
tissue,
particularly
epicardial
tissue
(EAT),
and
effects
sleep-disordered
breathing
(SDB).
Understanding
these
intricate
relationships
is
pivotal
for
devising
targeted
therapeutic
approaches
to
alleviate
burden
individuals
obesity.
EAT
assumes
central
role
linking
obesity
HFpEF.
As
it
expands
context
obesity,
contributes
systemic
inflammation
insulin
resistance,
fostering
an
environment
conducive
cardiac
remodeling
dysfunction.
Furthermore,
SDB,
prevalent
comorbidity
obese
population,
emerges
mediator
through
various
mechanisms.
The
convergence
expansion,
SDB
creates
synergistic
effect,
heightening
development.
On
pharmaceutical
front,
ongoing
investigations
explore
novel
strategies
targeting
inflammation,
oxidative
stress,
pathways
associated
These
include
potential
roles
sodium-glucose
cotransporter
2
inhibitors
glucagon-like
peptide-1
receptor
agonists,
offering
innovative
avenues
managing
In
addition,
lifestyle
modifications
such
weight
management
interventions
addressing
reduction
emerge
promising
preventing
population.
hold
mitigate
obesity-related
risks
improve
outcomes.
Language: Английский
Role of epicardial adipose tissue in cardiac remodeling
Rongjun Zou,
No information about this author
Miao Zhang,
No information about this author
Weihui Lv
No information about this author
et al.
Diabetes Research and Clinical Practice,
Journal Year:
2024,
Volume and Issue:
unknown, P. 111878 - 111878
Published: Oct. 1, 2024
Language: Английский
Research Progress of TyG Index in Cardiovascular Diseases
玉宁 王
No information about this author
Advances in Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
14(03), P. 1788 - 1794
Published: Jan. 1, 2024
Language: Английский
Can the triglyceride-glucose index alone illuminate the relationship between epicardial fat volume and both insulin resistance and inflammation in patients with chronic heart failure?
The International Journal of Cardiovascular Imaging,
Journal Year:
2024,
Volume and Issue:
40(8), P. 1813 - 1814
Published: April 13, 2024
Language: Английский