Progress in personalized immunotherapy for patients with brain metastasis DOI Creative Commons
Lalit R. Patel, Nikola Kolundžić, Malak Abedalthagafi

et al.

npj Precision Oncology, Journal Year: 2025, Volume and Issue: 9(1)

Published: Jan. 29, 2025

Brain metastasis leads to poor outcomes and CNS injury, significantly reducing quality of life survival rates. Advances in understanding the tumor immune microenvironment have revealed promise immunotherapies, which, alongside surgery, chemotherapy, radiation, offer improved for some patients. However, resistance immunotherapy remains a critical challenge. This review explores landscape brain metastases, current therapies, clinical trials, need personalized, biomarker-driven approaches optimize outcomes.

Language: Английский

Progress in personalized immunotherapy for patients with brain metastasis DOI Creative Commons
Lalit R. Patel, Nikola Kolundžić, Malak Abedalthagafi

et al.

npj Precision Oncology, Journal Year: 2025, Volume and Issue: 9(1)

Published: Jan. 29, 2025

Brain metastasis leads to poor outcomes and CNS injury, significantly reducing quality of life survival rates. Advances in understanding the tumor immune microenvironment have revealed promise immunotherapies, which, alongside surgery, chemotherapy, radiation, offer improved for some patients. However, resistance immunotherapy remains a critical challenge. This review explores landscape brain metastases, current therapies, clinical trials, need personalized, biomarker-driven approaches optimize outcomes.

Language: Английский

Citations

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