Mitochondrial DNA copy number and its association with venous thromboembolism in patients with cancer

Thrombosis Research, Journal Year: 2025, Volume and Issue: 248, P. 109285 - 109285

Published: Feb. 13, 2025

Language: Английский

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Invisible Bridges: Unveiling the Role and Prospects of Tunneling Nanotubes in Cancer Therapy

Molecular Pharmaceutics, Journal Year: 2024, Volume and Issue: 21(11), P. 5413 - 5429

Published: Oct. 7, 2024

Tunneling nanotubes (TNTs) are essential intercellular communication channels that significantly impact cancer pathophysiology, affecting tumor progression and resistance. This review methodically examines the mechanisms of TNTs formation, their structural characteristics, functional roles in material signal transmission between cells. Highlighting regulatory functions within microenvironment, crucial for modulating cell survival, proliferation, drug resistance, immune evasion. The critically evaluates therapeutic potential TNTs, focusing on applications targeted delivery gene therapy. It also proposes future research directions to thoroughly understand biogenesis, identify cell-specific molecular targets, develop advanced technologies real-time monitoring TNTs. By integrating insights from biology, nanotechnology, immunology, this highlights transformative advancing treatment strategies.

Language: Английский

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Characterization of the Mitochondria Function and Metabolism in Skin Fibroblasts Using the Biolog MitoPlate S-1

Methods in molecular biology, Journal Year: 2024, Volume and Issue: unknown, P. 75 - 98

Published: Nov. 15, 2024

Language: Английский

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Research progress of mitochondria and cytoskeleton crosstalk in tumour development

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Journal Year: 2024, Volume and Issue: 1880(1), P. 189254 - 189254

Published: Dec. 26, 2024

Language: Английский

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