Effects of alpha-cypermethrin and difenoconazole on survival, growth and biomarkers in European green toad tadpoles (<em>Bufotes viridis</em>, Laurenti 1768) DOI Creative Commons

Bruno Bekić,

Anamarija Žagar, Tatjana Simčić

et al.

Basic and Applied Herpetology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 17, 2024

In recent decades, the decline of amphibian populations has become more pronounced and accelerated, with one contributing factors being excessive use pesticides. Alpha-cypermethrin, an insecticide, difenoconazole, a fungicide, are widely employed pesticides globally. To gain comprehensive understanding acute impact these two on amphibians, we used European green toad (Bufotes viridis) tadpoles as our model organisms. We assessed mortality mass apical endpoints, examined physiological biomarkers including electron transport system (ETS) activity, catalase carbonyl protein content. Tadpoles were exposed to varying concentrations for 48 hours (0.2-10 µg/L alpha-cypermethrin; 10-100 difenoconazole). Our results indicate that exposure significantly affected their physiology. Mortality was observed exclusively in treated difenoconazole (LC50 = 100.832 µg/L), while decrease occurred both No significant differences across treatments found total ETS or presence carbonyls. conclusion, findings suggest alpha-cypermethrin at environmentally relevant poses risk tadpoles, effects patent higher than those recorded natural aquatic environments.

Language: Английский

Influence of climate change and pesticide use practices on the ecological risks of pesticides in a protected Mediterranean wetland: A Bayesian network approach DOI Creative Commons
Claudia Martínez‐Megías, Sophie Mentzel,

Yasser Fuentes-Edfuf

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 878, P. 163018 - 163018

Published: March 22, 2023

Pollution by agricultural pesticides is one of the most important pressures affecting Mediterranean coastal wetlands. Pesticide risks are expected to be influenced climate change, which will result in an increase temperatures and a decrease annual precipitation. On other hand, pesticide dosages change given pest resistance implementation environmental policies like European ´Farm-to-Fork` strategy, aims for 50 % reduction usage 2030. The influence use practices on ecological needs evaluated making realistic scenarios. This study investigates how different affect Albufera Natural Park (Valencia, Spain), protected wetland. We performed probabilistic risk assessment nine applied rice production using three climatic scenarios (for years 2008, 2050 2100), dosage regimes (the recommended dose, decrease), their combinations. were used simulate exposure concentrations water column paddies RICEWQ model. effects characterized acute chronic Species Sensitivity Distributions built with toxicity data aquatic organisms. Risk quotients calculated as probability distributions Bayesian networks. Our results show that future projections some studied pesticides, yielding higher dissipation lower dominated temperatures, peaks where heavy precipitation events occur right after application. case shows such azoxystrobin, difenoconazole MCPA posing unacceptable organisms, strategy crucial reduce them.

Language: Английский

Citations

37
“Fishcide” effect of the fungicide difenoconazole in freshwater fish (Labeo rohita): A multi-endpoint approach DOI

Bojan Nataraj,

Devan Hemalatha, Guilherme Malafaia

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 857, P. 159425 - 159425

Published: Oct. 14, 2022

Language: Английский

Citations

22
Pathway-dependent toxic interaction between polystyrene microbeads and methylmercury on the brackish water flea Diaphanosoma celebensis: Based on mercury bioaccumulation, cytotoxicity, and transcriptomic analysis DOI

Je-Won Yoo,

Tae-June Choi,

Jong Seok Park

et al.

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 459, P. 132055 - 132055

Published: July 12, 2023

Language: Английский

Citations

10
MAPK-CncC Signaling Pathways Regulate the Antitoxic Response to Avermectin-Induced Oxidative Stress in Juvenile Chinese Mitten Crab, Eriocheir sinensis DOI
Yi Huang, Yuhang Hong, Shu Wu

et al.

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 30, 2025

This study delves into the adverse effects of AVM, emphasizing oxidative stress induction in Chinese mitten crab, Erocheir sinensis, and role MAPK-CncC signaling pathway mediating antioxidative response. Our findings reveal a dose-dependent impairment growth performance, alongside occurrence stress. The activity CAT superoxide dismutase increased significantly all treatments (0.2, 2, 20 μg/L) while lipid peroxidation level rose median (2 high (20 concentration groups. T-AOC levels decreased reactive oxygen species significantly. Transcriptomic insights indicated activation pathway, critical upregulating genes associated with detoxification defense. Knocking down CncC, homologue vertebrate Nrf2 gene, by dsRNA E. sinensis resulted down-regulation reduced survival tolerance to AVM exposure. By using an vitro cell culture system, we observed similar downregulations when hepatopancreas cells were treated ML385, CncC specific inhibitor. Moreover, rapid phosphorylation JNK protein was upon When inhibited, more vulnerable AVM-induced robust expression gene blocked.

Language: Английский

Citations

0
Toxicity of fipronil and 2,4-D formulations (alone and in a mixture) to the tropical amphipod Hyalella meinerti DOI
Thandy Júnio da Silva Pinto, Raquel Aparecida Moreira, Laís Conceição Menezes da Silva

et al.

Environmental Science and Pollution Research, Journal Year: 2021, Volume and Issue: 28(28), P. 38308 - 38321

Published: March 17, 2021

Language: Английский

Citations

23
Time-Dependent Naphthalene Toxicity in Anabas testudineus (Bloch): A Multiple Endpoint Biomarker Approach DOI Creative Commons
Sukhendu Dey,

Puspita Ballav,

Palas Samanta

et al.

ACS Omega, Journal Year: 2020, Volume and Issue: 6(1), P. 317 - 326

Published: Dec. 18, 2020

Polyaromatic compounds are the major, widespread contaminants in aquatic environment. However, adverse impacts of these on blood pathophysiology (hematological profiling and serum biochemical responses) poorly understood. As a consequence, this study was intended to evaluate toxic effects naphthalene, one polycyclic aromatic hydrocarbons, Anabas testudineus using multiple end-point biomarker approach. A. exposed short-term (1 5 d) long-term (10, 15, 21 naphthalene concentrations, that is, T1 (0.71 mg/L indicates 25% LC50) T2 (1.42 50% LC50 value). The results disclosed significant decrease red cells, hemoglobin (Hb), packed cell volume, platelet levels, while other parameters, namely, white percent lymphocyte, mean corpuscular Hb, Hb concentration showed enhanced levels under intoxication. Results were more detrimental concentration. Cholesterol, glucose, calcium, high-density lipoprotein, low-density lipoprotein gradually increased throughout different exposure periods triglyceride level decreased during periods. Finally, integrated responses (IBR) analysis indicated parameters powerful than hematological for determining naphthalene-induced fish health status. Additionally, IBR clearly identified (>5 harmful (<5 exposure. So, may be derived as biomarkers monitoring pollution an ecosystem.

Language: Английский

Citations

21
Acute toxicity of the insecticide abamectin and the fungicide difenoconazole (individually and in mixture) to the tropical stingless bee Melipona scutellaris DOI

Janete Brigante,

Joyce Oliveira Costa, Evaldo Luiz Gaeta Espíndola

et al.

Ecotoxicology, Journal Year: 2021, Volume and Issue: 30(9), P. 1872 - 1879

Published: Aug. 11, 2021

Language: Английский

Citations

20
The sexual reproduction of the nontarget planarian Girardia tigrina is affected by ecologically relevant concentrations of difenoconazole: new sensitive tools in ecotoxicology DOI
Aline Silvestre Pereira Dornelas, Joel Santiago de Jesus Ferreira,

Laila Cristina Rezende Silva

et al.

Environmental Science and Pollution Research, Journal Year: 2022, Volume and Issue: 29(18), P. 27095 - 27103

Published: Jan. 3, 2022

Language: Английский

Citations

12
Toxicity of Difenoconazole and Atrazine and Their Photodegradation Products on Aquatic Biota: Environmental Implications in Countries Lacking Good Agricultural Practices DOI Creative Commons

Julia Mendieta Herrera,

Carlos Iñiguez‐Armijos,

Daniel Rosado Alcarria

et al.

Toxics, Journal Year: 2023, Volume and Issue: 11(3), P. 213 - 213

Published: Feb. 24, 2023

Agriculture is fundamental for human development, but it may also have a range of unwanted effects on ecosystems when pesticides inadvertently enter the environment. We determined toxicity difenoconazole and atrazine, as well their photodegradation products, bioindicators Lemna minor Daphnia magna. For L. minor, we assessed number leaves, biomass, chlorophyll content exposed to different concentrations (0–8 mg/L) atrazine (0–3.84 mg/L). D. magna, mortality (0–1.6 (0–80 found that higher pesticides, both bioindicators. In highest was 0.96 mg/L, whereas difenoconazole, 8 mg/L. 48 h LC50 0.97 while 86.19 not compared products. contrast, more toxic its respective Pesticides are serious threat aquatic biota, products remain in Additionally, use can help monitor these pollutants countries where application imperative agricultural production.

Language: Английский

Citations

6
Aquatic and sediment ecotoxicity data of difenoconazole and its potential environmental risks in ponds bordering rice paddies DOI Creative Commons
Jian Sun, Pengfei Xiao, Xiaohui Yin

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 273, P. 116135 - 116135

Published: Feb. 24, 2024

Language: Английский

Citations

2