Artificial Spidroin Nanogenerator‐Based Articulus Wound Dressing DOI Creative Commons

Xiaoming Ma,

Shuhuan Li, Bingbing Gao

et al.

ChemistryOpen, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 30, 2024

Abstract Articulus wound infection is a threat to human health. Existing medical materials have poor biocompatibility and may contain harmful chemicals, causing allergies secondary infections. Therefore, there an urgent need develop innovative materials. Materials made of artificial spider silk proteins been widely used in healing because their good biocompatibility, biodegradability, cell adhesion bioelectronic properties.

Language: Английский

The histopathological and functional consequences of microplastic exposure DOI Creative Commons

Yujeong Lee,

Min Kyung Sung, Soo‐Eun Sung

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 7(1)

Published: Jan. 11, 2025

As the production, usage, and disposal of plastics increase, microplastics generated—plastic particles smaller than 5 mm—increases, exacerbating environmental pollution. In turn, various organisms become increasingly exposed to contaminated environments, potentially affecting humans through food chain. Crucial findings from in vivo experiments indicate histopathological changes caused by impact morphology physiological function organisms. This study describes induced across circulatory, nervous, digestive, respiratory, reproductive systems explains associated functional alterations. Except nervous system, main morphological involve degenerative throughout body, such as apoptosis, inflammation, fibrosis. Most were inflammatory responses microplastics, leading fibrosis subsequent impairments. Various studies confirm that stimulate cells, increased reactive oxygen species cell death. Consequently, these impair related systemic functions. review highlights fundamental organs cells due discusses limitations involving showing no changes.

Language: Английский

Citations

2
Overexpressed Artificial Spidroin Based Microneedle Spinneret for 3D Air Spinning of Hybrid Spider Silk DOI

Baoyang Lin,

Bingbing Gao, Wei Meng

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(37), P. 25778 - 25794

Published: Sept. 2, 2024

Efforts have been devoted to developing strategies for converting spider silk proteins (spidroins) into functional materials. However, studies mimicking the exact natural spinning process of spiders encounter arduous challenges. In this paper, consistent with spiders, we report a high-efficient strategy that enables mass preparation multifunctional artificial at different scales. By simulating structural stability mechanism cross-β-spine amyloid polypeptide by computer dynamics, designed and obtained an spidroin significantly increased yield (13.5 g/L). Using spidroin, fabricated glands (hollow MNs). Notably, combining 3D printing, perform patterned air macro- microscales, resulting has excellent pump-free liquid flow conductive frictional electrical properties. Based on these findings, used macroscale treat rheumatoid arthritis in mice micro prepare wound dressings diabetic mice. We believe based will provide way construct modulate next generation smart

Language: Английский

Citations

4
Polystyrene microplastics cause reproductive toxicity in male mice DOI
Somaye Zangene, Hassan Morovvati, Hojat Anbara

et al.

Food and Chemical Toxicology, Journal Year: 2024, Volume and Issue: 194, P. 115083 - 115083

Published: Nov. 7, 2024

Language: Английский

Citations

4
Selenium Homeostasis and Male Reproduction DOI
Dan Yang, Chenhui Zhang, Jing Ma

et al.

Biochemical and Biophysical Research Communications, Journal Year: 2025, Volume and Issue: unknown, P. 151879 - 151879

Published: April 1, 2025

Language: Английский

Citations

0
Microplastics exposure causes premature ovarian aging via inducing mitochondrial dysfunction DOI
Xing Duan,

Li‐Shu Li,

Wen-Jiao Liu

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Abstract Ovarian aging represents a significant risk factor for female infertility, primarily due to decline in ovarian reserve and diminished oocyte quality. However, whether microplastics (MPs) exposure poses potential inducing the underlying mechanisms remain poorly understood. In this study, we demonstrated that MPs accelerates aging, characterized by elevated expression of senescence markers (p16 p21) increased fibrosis. Mechanistic analysis indicated led inflammatory damage mitochondrial dysfunction, which contribute reduced reserve. Furthermore, compromised maturation competence embryo development triggering dysfunction DNA damage. Multi-omics identified L-arginine as crucial metabolite protects oocytes from MPs-induced aging. Notably, supplementation significantly mitigated phenotypes induced MPs, evidenced fibrosis, damage, alongside enhanced These findings provide theoretical support reproductive protection against inform environmental assessments.

Language: Английский

Citations

0
Mitigating Microplastic-Induced Organ Damage: Mechanistic Insights from the Microplastic-Macrophage Axes DOI Creative Commons

Yinxing Cui,

Yuqi Wu,

Shi Pan

et al.

Redox Biology, Journal Year: 2025, Volume and Issue: unknown, P. 103688 - 103688

Published: May 1, 2025

Language: Английский

Citations

0
Artificial spidroin bioelectronic dressings for intelligent wound management DOI
Shuhuan Li,

Baoyang Lin,

Yongji Xiong

et al.

Journal of Materials Chemistry C, Journal Year: 2024, Volume and Issue: 12(33), P. 12708 - 12720

Published: Jan. 1, 2024

Wound infection has always been a huge threat to human health.

Language: Английский

Citations

0
Artificial Spidroin Nanogenerator‐Based Articulus Wound Dressing DOI Creative Commons

Xiaoming Ma,

Shuhuan Li, Bingbing Gao

et al.

ChemistryOpen, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 30, 2024

Abstract Articulus wound infection is a threat to human health. Existing medical materials have poor biocompatibility and may contain harmful chemicals, causing allergies secondary infections. Therefore, there an urgent need develop innovative materials. Materials made of artificial spider silk proteins been widely used in healing because their good biocompatibility, biodegradability, cell adhesion bioelectronic properties.

Language: Английский

Citations

0