Increase from low to moderate, but not high, caffeinated coffee consumption is associated with favorable changes in body fat DOI Creative Commons
Matthias Henn, Nancy Babió, Dora Romaguera

et al.

Clinical Nutrition, Journal Year: 2023, Volume and Issue: 42(4), P. 477 - 485

Published: Feb. 11, 2023

Higher consumption of coffee and caffeine has been linked to less weight gain lower body mass index in prospective cohort studies. The aim the study was longitudinally assess association changes intake with fat tissue, particular, visceral adipose tissue (VAT) using dual x-ray absorptiometry (DXA).In setting a large, randomized trial Mediterranean diet physical activity intervention, we evaluated 1483 participants metabolic syndrome (MetS). Repeated measurements from validated food frequency questionnaires (FFQ) DXA were collected at baseline, 6 months, 12 months 3 years follow-up. DXA-derived total regional expressed as % transformed into sex-specific z-scores. Linear multilevel mixed-effect models used investigate relationship between corresponding concurrent during 3-year follow-up.After adjustment for intervention group, other potential confounders, an increase caffeinated no or infrequent (≤3 cups/month) moderate (1-7 cups/week) associated reductions (Δ z-score: -0.06; 95% CI: -0.11 -0.02), trunk -0.07; -0.12 VAT -0.13 -0.01). Neither high levels (>1 cup/day) nor any decaffeinated showed significant associations measures.Moderate coffee, but not consumption, fat, MetS. Decaffeinated adiposity indicators. Moderate may be part management strategy.The registered International Standard Randomized Controlled Trial (ISRCTN: http://www.isrctn.com/ISRCTN89898870) number 89898870 registration date 24 July 2014, retrospectively registered.

Language: Английский

Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes DOI Creative Commons
Robin Poole, Oliver John Kennedy, Paul Roderick

et al.

BMJ, Journal Year: 2017, Volume and Issue: unknown, P. j5024 - j5024

Published: Nov. 22, 2017

To evaluate the existing evidence for associations between coffee consumption and multiple health outcomes.

Language: Английский

Citations

642
The Rotterdam Study: 2018 update on objectives, design and main results DOI Creative Commons
M. Arfan Ikram, Guy Brusselle, Sarwa Darwish Murad

et al.

European Journal of Epidemiology, Journal Year: 2017, Volume and Issue: 32(9), P. 807 - 850

Published: Sept. 1, 2017

The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Netherlands. targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, dermatological, otolaryngological, locomotor, and respiratory diseases. As 2008, 14,926 subjects aged 45 years or over comprise cohort. Since 2016, being expanded by persons 40 over. findings have been presented 1500 research articles reports (see www.erasmus-epidemiology.nl/rotterdamstudy ). This article gives rationale its design. It also presents summary major an update objectives methods.

Language: Английский

Citations

418
Dietary Inflammatory Index and Colorectal Cancer Risk—A Meta-Analysis DOI Open Access
Nitin Shivappa, Justyna Godos, James R. Hébert

et al.

Nutrients, Journal Year: 2017, Volume and Issue: 9(9), P. 1043 - 1043

Published: Sept. 20, 2017

Diet and chronic inflammation of the colon have been suggested to be risk factors in development colorectal cancer (CRC). The possible link between inflammatory potential diet, measured through Dietary Inflammatory Index (DII®), CRC has investigated several populations across world. aim this study was conduct a meta-analysis on studies exploring association. Data from nine were eligible, which five case-control four cohort studies. Results showed positive association increasing DII scores, indicating pro-inflammatory CRC. Individuals highest versus lowest (reference) category an overall 40% increased with moderate evidence heterogeneity [relative (RR) = 1.40, 95% confidence interval (CI): 1.26, 1.55; I2 69%, p < 0.001]. When analyzed as continuous variable, results 7% for 1-point increase score. remained unchanged when analyses restricted prospective our support importance adopting healthier anti-inflammatory diet preventing These further substantiate utility tool characterize predict

Language: Английский

Citations

196
Caffeine and cardiovascular health DOI Creative Commons
Duncan Turnbull, Joseph V. Rodricks,

Gregory F. Mariano

et al.

Regulatory Toxicology and Pharmacology, Journal Year: 2017, Volume and Issue: 89, P. 165 - 185

Published: July 26, 2017

This report evaluates the scientific literature on caffeine with respect to potential cardiovascular outcomes, specifically relative risks of total disease (CVD), coronary heart (CHD) and acute myocardial infarction (AMI), effects arrhythmia, failure, sudden cardiac arrest, stroke, blood pressure, hypertension, other biomarkers effect, including rate, cerebral flow, output, plasma homocysteine levels, serum cholesterol electrocardiogram (EKG) parameters, rate variability, endothelial/platelet function plasma/urine catecholamine levels. Caffeine intake has been associated a range reversible transient physiological broadly specifically. attempts understand where delineations exist in corresponding among various subpopulations. The available suggests that experienced by consumers at levels up 600 mg/day are most cases mild, transient, reversible, no lasting adverse effect. point which may cause harm system is not readily identifiable part because data daily intakes greater than mg limited. However, evidence considered within this review typical moderate increased disease; arrhythmia; failure; pressure changes regular coffee drinkers; or hypertension baseline populations.

Language: Английский

Citations

174
Caffeine Consumption through Coffee: Content in the Beverage, Metabolism, Health Benefits and Risks DOI Creative Commons
Juliana DePaula, Adriana Farah

Beverages, Journal Year: 2019, Volume and Issue: 5(2), P. 37 - 37

Published: June 1, 2019

Caffeine (1,3,7-trimethylxanthine) is the most consumed psychoactive substance in world, acting by means of antagonism to adenosine receptors, mainly A1 and A2A. Coffee main natural source alkaloid which quite soluble well extracted during brew’s preparation. After consumption, caffeine almost completely absorbed extensively metabolized liver phase I (cytochrome P450) enzymes, CYP1A2, appears be polymorphically distributed human populations. Paraxanthine major metabolite plasma, while methylated xanthines methyluric acids are metabolites excreted urine. In addition stimulating central nervous system, exerts positive effects body, often association with other substances, contributing prevention several chronic diseases. The potential adverse have also been studied animal species humans. These aspects will approached present review.

Language: Английский

Citations

163
Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality DOI
Dan Liu, Zhihao Li, Dong Shen

et al.

Annals of Internal Medicine, Journal Year: 2022, Volume and Issue: 175(7), P. 909 - 917

Published: May 30, 2022

Background: Previous observational studies have suggested an association between coffee intake and reduced risk for death, but these did not distinguish consumed with sugar or artificial sweeteners without. Objective: To evaluate the associations of consumption sugar-sweetened, artificially sweetened, unsweetened all-cause cause-specific mortality. Design: Prospective cohort study. Setting: Data were extracted from UK Biobank. Participants: A total 171 616 participants (mean age, 55.6 years [SD, 7.9]) without cardiovascular disease (CVD) cancer at baseline eligible. Baseline demographic, lifestyle, dietary data Biobank used, follow-up beginning in 2009 ending 2018. Measurements: Dietary was self-reported. All-cause, cancer-related, CVD-related mortality estimated. Results: During a median 7.0 years, 3177 deaths recorded (including 1725 628 CVD deaths). Cox models penalized splines showed U-shaped coffee, sugar-sweetened sweetened Compared nonconsumers, consumers various amounts (>0 to 1.5, >1.5 2.5, >2.5 3.5, >3.5 4.5, >4.5 drinks/d) had lower risks after adjustment sociodemographic, clinical factors, respective hazard ratios 0.79 (95% CI, 0.70 0.90), 0.84 (CI, 0.74 0.95), 0.71 0.62 0.82), 0.60 0.84), 0.77 0.65 0.91); estimates 0.91 0.78 1.07), 0.69 0.57 0.72 0.91), 1.06), 1.05 0.82 1.36). The less consistent. drinking largely consistent that also observed instant, ground, decaffeinated coffee. Limitation: Exposure assessed might capture changes over time. Conclusion: Moderate associated death. Primary Funding Source: National Natural Science Foundation China, Young Elite Scientist Sponsorship Program by CAST, Project Supported Guangdong Basic Applied Research Foundation.

Language: Английский

Citations

78
Association between dietary patterns and cardiovascular diseases: A review DOI

Lijun Lu,

Wangwei Jing,

Weiming Qian

et al.

Current Problems in Cardiology, Journal Year: 2024, Volume and Issue: 49(3), P. 102412 - 102412

Published: Jan. 24, 2024

Language: Английский

Citations

18
Coffee drinking timing and mortality in US adults DOI Creative Commons
Xuan Wang, Hao Ma, Qi Sun

et al.

European Heart Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 8, 2025

Abstract Background and Aims To identify the patterns of coffee drinking timing in US population evaluate their associations with all-cause cause-specific mortality. Methods This study included 40 725 adults from National Health Nutrition Examination Survey 1999–2018 who had complete information on dietary data 1463 Women’s Men’s Lifestyle Validation Study 7-day record. Clustering analysis was used to timing. Results In this observational study, two distinct [morning type (36% participants) all-day-type (14% participants)] were identified validated Study. During a median (interquartile range) follow-up 9.8 (9.1) years, total 4295 deaths, 1268 cardiovascular disease 934 cancer deaths recorded. After adjustment for caffeinated decaffeinated intake amounts, sleep hours, other confounders, morning-type pattern, rather than significantly associated lower risks (hazard ratio: .84; 95% confidential interval: .74–.95) disease-specific .69; .55–.87) mortality as compared non-coffee drinking. Coffee modified association between amounts (P-interaction = .031); higher risk participants pattern but not those pattern. Conclusions Drinking morning may be more strongly later day.

Language: Английский

Citations

7
Coffee consumption and all-cause and cause-specific mortality: a meta-analysis by potential modifiers DOI
Youngyo Kim, Youjin Je,

Edward L. Giovannucci

et al.

European Journal of Epidemiology, Journal Year: 2019, Volume and Issue: 34(8), P. 731 - 752

Published: May 4, 2019

Language: Английский

Citations

128
Acidity and Antioxidant Activity of Cold Brew Coffee DOI Creative Commons
Niny Z. Rao, Megan Fuller

Scientific Reports, Journal Year: 2018, Volume and Issue: 8(1)

Published: Oct. 24, 2018

Abstract The acidity and antioxidant activity of cold brew coffee were investigated using light roast coffees from Brazil, two regions Ethiopia, Columbia, Myanmar, Mexico. concentrations three caffeoylquinic acid (CQA) isomers also determined. Cold chemistry was compared to that hot prepared with the same grind-to-coffee ratio. pH values samples found be comparable, ranging 4.85 5.13. have higher total titratable acids, as well activity, than their counterparts. It noted both concentration acids correlated poorly CQA in coffee. This work suggests method tends extract more non-deprotonated method. These may responsible for activities observed samples.

Language: Английский

Citations

109