Thyroid under Attack: The Adverse Impact of Plasticizers, Pesticides, and PFASs on Thyroid Function DOI Creative Commons
V Rodrigues, Guilherme Henrique,

Érica Kássia Sousa-Vidal

et al.

Endocrines, Journal Year: 2024, Volume and Issue: 5(3), P. 430 - 453

Published: Sept. 19, 2024

Endocrine-disrupting chemicals (EDCs) are synthetic or natural compounds that interfere with the endocrine system, inducing harmful effects on organisms depending dose and period of exposure. Numerous studies have identified concerning amounts EDCs in environmental human samples. The thyroid gland is essential for hormone production controls several body functions. Several been classified as disruptors, impairing production, synthesis, metabolism, transport, and/or actions. Notably, disorders second most prevalent disease worldwide, incidence increasing significantly recent years. Some correlated this rise dysfunctions cancers increased exposure to EDCs. Although many linked dysfunction, review focuses deleterious plasticizers, organochlorine pesticides, per- poly-fluoroalkyl substances function. These contaminants commonly found food, water, everyday products. impact these controversial, numerous epidemiological, vivo, vitro indicated their Given critical role function growth, development, summarizes consequences disruptors health.

Language: Английский

Thyroid under Attack: The Adverse Impact of Plasticizers, Pesticides, and PFASs on Thyroid Function DOI Creative Commons
V Rodrigues, Guilherme Henrique,

Érica Kássia Sousa-Vidal

et al.

Endocrines, Journal Year: 2024, Volume and Issue: 5(3), P. 430 - 453

Published: Sept. 19, 2024

Endocrine-disrupting chemicals (EDCs) are synthetic or natural compounds that interfere with the endocrine system, inducing harmful effects on organisms depending dose and period of exposure. Numerous studies have identified concerning amounts EDCs in environmental human samples. The thyroid gland is essential for hormone production controls several body functions. Several been classified as disruptors, impairing production, synthesis, metabolism, transport, and/or actions. Notably, disorders second most prevalent disease worldwide, incidence increasing significantly recent years. Some correlated this rise dysfunctions cancers increased exposure to EDCs. Although many linked dysfunction, review focuses deleterious plasticizers, organochlorine pesticides, per- poly-fluoroalkyl substances function. These contaminants commonly found food, water, everyday products. impact these controversial, numerous epidemiological, vivo, vitro indicated their Given critical role function growth, development, summarizes consequences disruptors health.

Language: Английский

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